Cross-Coupling reactions are potential tools for construction of complex molecular frameworks of diversified interests via formation of carbon-carbon (C-C) or carbon-heteroatom (C-X) linkage. Compared with conventional transition metal-catalyzed cross-couplings and oxidative cross-couplings, photocatalytic hydrogen-evolution cross-couplings allow used of less functionalized reagents and proceed without any sacrificial oxidant under mild conditions and by visible-light irradiation. The reactions generally afford the desired cross-coupling products with excellent yields, and hydrogen gas is the only byproduct. In this presentation we will highlight the progress achieved by these reactions since the term “photocatalytic hydrogen-evolution cross-coupling” was established in 2013 by our group.
Q.-Y. Meng, J.-J. Zhong, Q. Liu, X.-W. Gao, H.-H. Zhang, T. Lei, Z.-J. Li, K. Feng, B. Chen, C.-H. Tung, L.-Z. Wu, J. Am. Chem. Soc., 2013, 135, 19052-19055.
X.-B. Li, Z.-J. Li, Y.-J. Gao, Q.-Y. Meng, S. Yu, R. G. Weiss, C.-H. Tung, L.-Z. Wu, Angew. Chem. Int. Ed., 2014, 53(8), 2085-2089.
G.-T. Zhang, C. Liu, H. Yi, Q.-Y. Meng, C.-L. Bian, H. Chen, J.-X. Jian, L.-Z. Wu, A.-W. Lei, J. Am. Chem. Soc., 2015, 137, 9273-9280.
Y.-W. Zheng, B. Chen, P. Ye, K. Feng, W.-G. Wang, Q.-Y. Meng, L.-Z. Wu, C.-H. Tung, J. Am. Chem. Soc., 2016, 138, 10080-10083.
Q.-Y. Meng, X.-W. Gao, T. Lei, Z. Liu, F. Zhan, Z.-J. Li, J.-J. Zhong, H. Xiao, K. Feng, B. Chen, Y. Tao, C.-H. Tung, L.-Z. Wu, Sci. Adv., 2017, 3, e1700666..
Q. Yang, L. Zhang, C. Ye, S.-Z. Luo, L.-Z. Wu, C.-H. Tung, Angew. Chem. Int. Ed., 2017, 56, 3694-3698..
L.-M. Zhao, Q.-Y. Meng, X.-B. Fan, C. Ye, B. Chen, V. Ramamurthy, C.-H. Tung, L.-Z. Wu, Angew. Chem. Int. Ed., 2017, 56, 3020-3024.
Chen-Ho Tung (Zhenhe Tong) is a Professor of Technical Institute of Physics and Chemistry and Academician of the Chinese Academy of Sciences. He graduated from the Department of Polymer Chemistry of University of Science and Technology of China in 1963 and received his Ph.D from the Department of Chemistry of Columbia University in 1983. He is chiefly engaged in the research on organic photochemistry, particularly on photoinduced electron transfer, energy transfer and photochemical conversion in supramolecular assemblies. He has published more than 400 papers in international journals.