孙茂忠

男， 江南大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

2019.01- 今 江南大学 研究员
2017.01-2018.12 新加坡南洋理工大学 博士后 导师：张华 教授
2013.09-2016.12 江南大学 博士
2010.09-2013.06 安徽农业大学 硕士
2006.09-2010.06 江苏师范大学 学士

研究领域和兴趣

纳米探针合成，化学测量，手性化学，精准医学分析，临床分析

主要业绩

围绕如何实现生命体系中复杂背景下，重要分子事件的动态分析这一科学问题，开展了手性纳米探针的制备及其在生物体内的精准测量，并取得了系列成果：（1）针对生命体系背景信号干扰严重的问题，实现了基于近红外光区强光学活性的手性纳米结构的定量分析；（2）针对细胞内成分动态变化，发展了基于“构象与尺度”匹配的手性纳米探针细胞生命过程精准测量新方法；（3）针对活体生物标志物难以精准测定，通过制备多功能手性纳米探针，实现多细胞复杂系统的响应分析。获得国家高层次人才特殊支持计划青年拔尖人才，中国化学会“青年人才托举工程”。

代表成果

1. Baimei Shi; Aihua Qu; Zongda Li; Yingcai Xiong; Jianjian Ji; Liguang Xu; Chuanlai Xu; Maozhong Sun*; Hua Kuang, Chiral Intranasal Nanovaccines as Antivirals for Respiratory Syncytial Virus, Advanced Materials, 2024, 36(41): 2408090.
2. Aihua Qu, Xiaoling Wu, Si Li, Maozhong Sun,* Liguang Xu, Hua Kuang*, An NIR-Responsive DNA-Mediated Nanotetrahedron Enhances the Clearance of Senescent Cells, Advanced Materials, 2020, 2000184.
3. Hongyu Zhang, Panpan Chen, Wenxiong Shi, Aihua Qu*, Maozhong Sun*, Hua Kuang, Renal Clearable Chiral Manganese Oxide Supraparticles for in vivo Detection of Metalloproteinase-9 in Early Cancer Diagnosis, Advanced Materials, 2024, 2415656.
4. Weiwei Wang, Jing Zhao, Changlong Hao, Shudong Hu, Chen Chen, Yi Cao, Zhengyu Xu, Jun Guo, Liguang Xu, Maozhong Sun, * Chuanlai Xu, and Hua Kuang. The development of chiral nanoparticles to target NK cells and CD8+ T cells for cancer immunotherapy. Advanced Materials, 2022, 34(16): 2109354.
5. Baimei Shi; Aihua Qu; Zongda Li; Yingcai Xiong; Jianjian Ji; Liguang Xu; Chuanlai Xu; Maozhong Sun*; Hua Kuang, Chiral Intranasal Nanovaccines as Antivirals for Respiratory Syncytial Virus, Advanced Materials, 2024, 36(41): 2408090.
6. Xiao Guo, Xiaoling Wu, Maozhong Sun*, Liguang Xu, Hua Kuang, Chuanlai Xu. Tetrahedron Probes for Ultrasensitive in Situ Detection of Telomerase and Surface Glycoprotein Activity in Living Cells. Analytical Chemistry, 2019， 92(2), 2310-2315.
7. Meiru Lu, Aihua Qu, Si Li, Maozhong Sun,* Liguang Xu, Hua Kuang,* and Chuanlai Xu, Mitochondria-Targeting Plasmonic Spiky Nanorods Increase the Elimination of Aging Cells in Vivo, Angewandte Chemie International Edition, 2020, 59(22), 8698-8705.
8. Weiwei Wang, Jing Zhao, Changlong Hao, Shudong Hu, Chen Chen, Yi Cao, Zhengyu Xu, Jun Guo, Liguang Xu, Maozhong Sun,* Chuanlai Xu, and Hua Kuang. The development of chiral nanoparticles to target NK cells and CD8+ T cells for cancer immunotherapy. Advanced Materials, 2022, 34(16): 2109354.
9. Zongda Li, Aihua Qu, Chuanlai Xu, Hua Kuang, Liguang Xu, and Maozhong Sun*. Chiral Aluminum Oxyhydroxide Supraparticles as Adjuvants. Advanced Materials, 2025, 2504458.
10. Panpan Chen, Weiwei Wang, Aihua Qu, Yihui Hua, Jéssica Cristiane Magalhães Ierich, André Farias de Moura*, Liguang Xu, Hua Kuang*, Chuanlai Xu, Maozhong Sun*. Reprogramming anti-tumor immunity through both NLRP3 inflammasome and cGAS-STING pathways by chiral nanoadjuvants. Science Bulletin, 2026. doi.org/10.1016/j.scib.2026.03.050

*以上信息由高级会员个人更新和维护。