付鹏

男， 中国海洋大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

2004.09~2008.06，中国海洋大学，药学，本科
2008.09~2013.06，中国海洋大学，药物化学，博士（硕博连读）
2013.07~2017.06，美国得克萨斯大学西南医学中心，博士后
2017.08至今，中国海洋大学，教授，博士生导师

研究领域和兴趣

海洋微生物天然药物化学

主要业绩

长期从事海洋微生物天然药物化学研究，主要研究方向包括新结构天然产物的发现、形成机制解析、结构多样性拓展及生物活性评价等。在Nature Communications、Natural Product Reports、Organic Letters等期刊发表SCI论文60余篇，参编学术专著1部。承担多项国家级及省部级科研项目。入选山东省泰山学者青年专家。兼任山东省青年医务工作者协会药物药理学分会委员、青岛市药学会中药与天然药物专业委员会青年副主任委员。

代表成果

1、Shupeng Yin, Zhi Liu, Jingjing Shen, Yuwei Xia, Weihong Wang, Pengyan Gui, Qian Jia, Konthorn Kachanuban, Weiming Zhu, Peng Fu. Chimeric natural products derived from medermycin and the nature-inspired construction of their polycyclic skeletons. Nat. Commun., 13(1) (2022), 5169. https://doi.org/10.1038/s41467-022-32901-0
2、Yaqin Fan, Jingjing Shen, Zhi Liu, Kunyu Xia, Weiming Zhu, Peng Fu. Methylene-bridged dimeric natural products involving one-carbon unit in biosynthesis. Nat. Prod. Rep., 39(6) (2022), 1305–1324. https://doi.org/10.1039/D2NP00022A
3、Rui Ma, Weiming Zhu, Peng Fu. Nonenzymatic Formation of Streptoindoles Reveals an Unexplored Chemical Space of Tryptamine-Derived Natural Products. Org. Lett., 27(43) (2025), 12206–12211. https://doi.org/10.1021/acs.orglett.5c04065
4、Zhi Liu, Chao Gao, Shan Cheng, Weiming Zhu, Peng Fu. Bioinspired One-Step Oxidative Cleavage of Paxilline Enables Rapid Generation of Indole Diterpenoid Derivatives with Antibiofilm Activity. Org. Lett., 27(38) (2025), 10825–10830. https://doi.org/10.1021/acs.orglett.5c03462
5、Jiaxu Shang, Shupeng Yin, Jingjing Shen, Chao Gao, Weihong Wang, Ke Sun, Weiming Zhu, Peng Fu. Amino-Based Probe for Natural Products with Covalent Binding Ability to Lysine and Mechanism of Action of Medermycin. Org. Lett., 26(47) (2024), 10129–10134. https://doi.org/10.1021/acs.orglett.4c03803
6、Rongxin Zhang, Xiaotang Yan, Shupeng Yin, Weihong Wang, Weiming Zhu, Peng Fu. Discovery of New Bohemamines and Synthesis of Methylene-Bridged Chimeric Derivatives through Natural Product Chimera Strategy. Chin. J. Chem., 40(12) (2022), 1413–1421. https://doi.org/10.1002/cjoc.202200034
7、Shan Cheng, Yanchao Xu, Meng Kang, Weiming Zhu, Liping Wang, Peng Fu. Aurovertins from a Marine-Derived Penicillium Species and Nonenzymatic Reactions in Their Formation. J. Nat. Prod., 88(2) (2025), 554–562. https://doi.org/10.1021/acs.jnatprod.4c01436
8、Weihong Wang, Jiaxu Shang, Shupeng Yin, Kunyu Xia, Rui Ma, Weiming Zhu, Peng Fu. Nonenzymatic Sequestering of Formaldehyde into the Antibiotic Methylene-Bridged Dimer Phaeochromycin F by Streptomyces sp. OUCMDZ-4982 as a Possible Multipronged Chemical Defense Mechanism. J. Nat. Prod., 87(11) (2024), 2580–2591. https://doi.org/10.1021/acs.jnatprod.4c00702
9、Jingjing Shen, Jiwen Sun, Shupeng Yin, Weiming Zhu, Peng Fu. Structurally Diverse Macrolactams from an Antarctic Streptomyces Species. J. Nat. Prod., 87(2) (2024), 404–414. https://doi.org/10.1021/acs.jnatprod.4c00032
10、Rui Ma, Shan Cheng, Jiwen Sun, Weiming Zhu, Peng Fu. Antibacterial Gilvocarcin-Type Aryl‑C‑Glycosides from a Soil-Derived Streptomyces Species. J. Nat. Prod., 85(10) (2022), 2282–2289. https://doi.org/10.1021/acs.jnatprod.2c00438

*以上信息由高级会员个人更新和维护。