储玲玲

女， 东华大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

2003.9-2007.6， 合肥工业大学，学士
2007.9-2012.6，中科院上海有机化学研究所，博士 (导师：卿凤翎研究员）
2012.7-2013.3，中科院上海有机化学研究所，研究助理
2013.3-2016.3， 美国普林斯顿大学，博士后（导师：David W. C. MacMillan 教授）
2016.9--至今，东华大学，教授

研究领域和兴趣

自由基化学、有机氟化学

主要业绩

独立工作以来，主要围绕“开壳层金属如何调控自由基成键反应的活性与立体选择性”这一关键科学问题开展研究，取得了系列创新性成果：提出并发展了氟效应调控策略，系统研究了基态镍物种与含氟自由基之间的耦合与成键规律，解决了金属-氟烷基中间体易发生b-F消除且还原消除难的问题；发展了激发态调控策略，率先建立了激发态金属介导的自由基不对称成键新模式，并首次揭示了激发态金属配合物通过内层电子转移诱导惰性C-N键均裂的新机制。基于上述策略与机制认识，发展了多类具有挑战性的自由基不对称成键新反应，为手性（含氟）功能分子的绿色高效合成提供了新途径，也为开壳层物种反应活性与选择性的协同调控提供了一些新研究思路。
以通讯作者在J. Am. Chem. Soc.(6篇), Angew. Chem. Int. Ed.(9篇), Nat. Commun.(5篇), Chem(1篇), Sci. Bull.(2篇), Chem. Soc. Rev.(1篇)等期刊发表论文60多篇，申请中国专利4项（授权2项），并受邀在Chem. Soc. Rev.等期刊撰写综述5篇及Wiley英文书章节2章。申请人先后荣获国家自然科学奖二等奖（排名二）、Thieme Chemistry Journals Award、上海市巾帼创新新秀奖、中国纺织工业联合会教师奖等多项荣誉，并入选国家青年千人、国家优秀青年科学基金项目（结题优秀）、上海市东方英才领军项目、上海市曙光计划等。申请人还应邀在ORCHEM2024, ISHHC20, Pacifichem2025, ICHAT (2026) 等国内外会议上作主题与邀请报告50余次。目前担任ACS Omega副主编，Accounts of Chemical Research编委、NSO编委、Science Bulletin青年编委等。

代表成果

1. Chen, Fan; Zhang, Qianwei; Li, Yingying; Yu, Zhi-Xiang; Chu, Lingling, Selective Hydrofunctionalization of Alkenyl Fluorides Enabled by Nickel-Catalyzed Hydrogen Atoms and Group Transfer: Reaction Development and Mechanistic Study. J. Am. Chem. Soc. 2024, 146, 11418-11431.
2. Qin, Jian; Li, Yingying; Hu, Yuntong; Huang, Zhonghou; Miao, Weihang; Chu, Lingling, Photoinduced Nickel-Catalyzed Homolytic C(sp(3))-N Bond Activation of Isonitriles for Selective Carbo- and Hydro-Cyanation of Alkynes. J. Am. Chem. Soc. 2024, 146 (40), 27583-27593.
3. Li, Ling; Hu, Zhen; Ren, Shuaikang; Arndtsen, Bruce A.; Chu, Lingling, Enantioselective Carbonylative Coupling Reactions: Merging Nickel-Based Selectivity and Photoredox Reactivity. J. Am. Chem. Soc. 2025, 147 (31), 28206-28214.
4. Guo, Lei; Yuan, Mingbin; Zhang, Yanyan; Wang, Fang; Zhu, Shengqing; Gutierrez, Osvaldo; Chu, Lingling, General Method for Enantioselective Three-Component Carboarylation of Alkenes Enabled by Visible-Light Dual Photoredox/Nickel Catalysis. J. Am. Chem. Soc. 2020, 142 (48), 20390-20399.
5. Li, L.; Tang, C.; Huang, G.; Zhu, S.; Bai, Y.; Chu, L., Metallaphotoredox-Catalyzed Acceptorless Dehydrogenative Carbonylation Employing Benzylic C horizontal line H Bonds as Limiting Substrates. Angew. Chem. Int. Ed. 2026, 65 (27), e9220846.
6. Li, Yingying; Gong, Xian; Yuan, Ye; Bai, Yuyang; Li, Huan; Chu, Lingling, Catalytic Asymmetric Synthesis of Chiral Allenylic Fluorides Enabled by Multiple Radical Sorting. Angew. Chem. Int. Ed. 2025, 64 (50), e202518286.
7. Fan, Yanmin; Huang, Zhonghou; Lu, Yi; Zhu, Shengqing; Chu, Lingling, Defluorinative Alkylboration of Alkenes Enabled by Dual Photoredox and Copper Catalysis. Angew. Chem. Int. Ed. 2024, 63 (5), e202315974.
8. Pan, Shiwei; Chen, Fan; Zhang, Yanyan; Shao, Liang; Chu, Lingling, Nickel-Catalyzed Markovnikov-Selective Hydrodifluoromethylation of Alkynes Using BrCF(2) H. Angew. Chem. Int. Ed. 2023, 62 (31), e202305426.
9. Li, Huan; Wang, Fang; Zhu, Shengqing; Chu, Lingling, Selective Fluoromethyl Couplings of Alkynes via Nickel Catalysis. Angew. Chem. Int. Ed. 2022, 61 (9), e202116725.
10. Zhao, Xian; Feng, Xiaoliang; Chen, Fan; Zhu, Shengqing; Qing, Feng-Ling; Chu, Lingling, Divergent Aminocarbonylations of Alkynes Enabled by Photoredox/Nickel Dual Catalysis. Angew. Chem. Int. Ed. 2021, 60 (51), 26511-26517.

*以上信息由高级会员个人更新和维护。