孙佳姝

女， 国家纳米科学中心， 教授/研究员/教授级高工或同等级别

学习/工作经历

2002.09-2006.07，北京理工大学高分子材料与工程系，本科
2006.09-2010.12，美国范德堡大学机械工程系，博士
2011.03-2013.03，国家纳米科学中心，助理研究员
2013.04-2015.03，国家纳米科学中心，副研究员
2015.03-2016.03，国家纳米科学中心，特聘研究员
2016.03-至今，国家纳米科学中心，研究员

研究领域和兴趣

分析化学，微流控技术，纳米生物医学

主要业绩

提出了微流控热泳测量的新理念，实现循环肿瘤标志物的高灵敏定量检测，拓展了肿瘤液体活检技术，为重大疾病诊疗开辟了新途径。（1）开发了微流体无标记分离新方法，提高复杂样本中循环肿瘤靶标的分离分辨率；（2）发展了微流控生物传感新策略，提升目标分子的检测灵敏度；（3）提出了微流控精准合成系统，高效制备功能纳米结构用于肿瘤诊疗等应用。近5年在Nat. Biomed. Eng.（1篇）, Nat. Commun.（1篇）, J. Am. Chem. Soc.（2篇）, Angew. Chem. Int.Ed.（2篇）, Adv. Mater.（2篇）, ACS Nano（5篇）, Nano Lett.（2篇）等期刊上发表论文50余篇。并应邀在Adv. Mater.等期刊撰写综述。研究成果被Nat. Nanotechnol. 和Chem. Rev.进行重点评述。先后主持国家自然科学委优秀青年基金（2016，结题优秀）和杰出青年基金（2020）等项目。担任《中国科学：化学》（Science China Chemistry）青年工作委员会委员、Analytical Chemistry 杂志the Early Career Board等。

代表成果

1. Zhao, Junxiang#; Liu, Chao#; Li, Yike; Ma, Yao; Deng, Jinqi; Li, Lele; Sun, Jiashu*; Thermophoretic Detection of Exosomal microRNAs by Nanoflares. Journal of the American Chemical Society 2020, 142, 4996-5001.
2. Li, Yike#; Liu, Chao#; Bai, Xuan#; Tian, Fei; Hu, Guoqing; Sun, Jiashu*; Enantiomorphic Microvortex-Enabled Supramolecular Sensing of Racemic Amino Acids by Using Achiral Building Blocks. Angewandte Chemie International Edition 2020, 59, 3486-3490.
3. Lin, Ling; Yi, Linglu; Zhao, Fanghao; Wu, Zengnan; Zheng, Yajing; Li, Nan; Lin, Jin-Ming*; Sun, Jiashu*; ATP-responsive Mitochondrial Probes for Monitoring Metabolic Processes of Glioma Stem Cells in a 3D Model. Chemical Science 2020, 11, 2744-2749.
4. Liu, Chao#; Zhao, Junxiang#; Tian, Fei; Cai, Lili; Zhang, Wei; Feng, Qiang; Chang, Jianqiao; Wan, Fangning; Yang, Yunjie; Dai, Bo; Cong, Yulong; Ding, Baoquan; Sun, Jiashu*; Tan, Weihong; Low-Cost Thermophoretic Profiling of Extracellular-Vesicle Surface Proteins for the Early Detection and Classification of Cancers. Nature Biomedical Engineering 2019, 3, 183-193.
5. Liu, Chao; Zhao, Junxiang; Tian, Fei; Chang, Jianqiao; Zhang, Wei; Sun, Jiashu*; λ-DNA- and Aptamer-Mediated Sorting and Analysis of Extracellular Vesicles. Journal of the American Chemical Society 2019, 141, 3817-3821.
6. Liu, Chao#; Feng, Qiang#; Sun, Jiashu*; Lipid Nanovesicles by Microfluidics: Manipulation, Synthesis and Drug Delivery. Advanced Materials 2019, 31, 1804788.
7. Liu, Chao; Zhang, Wei; Li, Yike; Chang, Jianqiao; Tian, Fei; Zhao, Fanghao; Ma, Yao; Sun, Jiashu*; Microfluidic Sonication to Assemble Exosome Membrane-Coated Nanoparticles for Immune Evasion-Mediated Targeting. Nano Letters 2019, 19, 7836-7844.
8. Sun, Jiashu#*; Li, Yike#; Yan, Fusheng#; Liu, Chao#; Sang, Yutao; Tian, Fei; Feng, Qiang; Duan, Pengfei; Zhang, Li; Shi, Xinghua; Ding, Baoquan*; Liu, Minghua*; Control Over the Emerging Chirality in Supramolecular Gels and Solutions by Chiral Microvortices in Milliseconds. Nature Communications 2018, 9, 2599.
9. Liu, Chao; Guo, Jiayi; Tian, Fei; Yang, Na; Yan, Fusheng; Ding, Yanping; Wei, JingYan; Hu, Guoqing*; Nie, Guangjun*; Sun, Jiashu*; Field-Free Isolation of Exosomes from Extracellular Vesicles by Microfluidic Viscoelastic Flows. ACS Nano 2017, 11, 6968-6976.
10. Jiang, Qiao#; Liu, Qing#; Shi, Yuefeng#; Wang, Zhen-Gang; Zhan, Pengfei; Liu, Jianbing; Liu, Chao; Wang, Hui; Shi, Xinghua; Zhang, Li; Sun, Jiashu*; Ding, Baoquan*; Liu, Minghua*; Stimulus-Responsive Plasmonic Chiral Signals of Gold Nanorods Organized on DNA Origami. Nano Letters 2017, 17, 7125-7130.

*以上信息由高级会员个人更新和维护。