李迪

男， 华东师范大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

1996.9-2000.7, 大连理工大学化学化工学院环境工程专业，本科
2000.9-2005.7, 中国科学院长春应用化学研究所，硕博连读，分析化学博士学位
2005.8-2008.2, 以色列耶路撒冷希伯来大学化学系，博士后
2008.3-2012.12, 中国科学院上海应用物理研究所，副研究员
2013.1-2018.1, 中国科学院上海应用物理研究所，研究员
2018.2-至今, 华东师范大学化学与分子工程学院，教授

研究领域和兴趣

单分子生物物理，DNA纳米技术，蛋白质-水相互作用

主要业绩

李迪博士主要研究兴趣为单分子反应荧光成像，发展了在复杂环境中发现目标分子并跟踪其分子结构变化的成像方法。实现了对单分子酶促反应，光电催化反应的成像，发现了若干稀有反应途径及中间产物。利用单分子反应成像提取的反应途径和决速步骤等关键信息，实现了对化学反应的精准调控。近年来以通讯作者身份在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Nature Commun.、Chem. Sci.、Nano Lett.、Anal. Chem.等高水平期刊发表论文50余篇，受邀为Springer出版社撰写英文学术专著2章。先后主持国家自然科学基金杰出青年基金（2022）和优秀青年基金（2012）等项目。

代表成果

1. Yingya Liu, Jihang Zhai, Shanshan Cao, Huiying Guo, Hengwei Zhang, Bo Song, Jiajia Guo, Dong Men*, Xiao He*, Di Li*, Single-Residue Solvation Perturbations Regulate Global Protein Architecture and Function, Nature Commun., 2026, 3754
2. An Yan, Yuhan Kong, Yuxiang Shang, Yifan Ge, Hang Xing*, Di Li*, Relocation of Endocytic Leaflet DNA Probes for Asymmetric and Week-Long Lysosomal Labeling, J. Am. Chem. Soc. 2026, 148,7751-7760
3. An Yan, Xiaoqing Chen, Jie He, Yifan Ge, Qing Liu, Dong Men, Ke Xu, Di Li*, Phosphorothioated DNA Engineered Liposomes as a General Platform for Stimuli-Responsive Cell-Specific Intracellular Delivery and Genome-Editing, Angew. Chem. Int. Ed. 2023, e202303973
4. Xiaoqing Chen, Qianyun Yang, Wenyan Kong, Yifan Ge,*, Jie He, An Yan, Di Li*, High Spatial-resolved Heat Manipulating Membrane Heterogeneity Alters Cellular Migration and Signaling, PNAS, 2023, 120, e2312603120
5. Jun-Gang Wang, Lifang Shi, Yingying Su, Liwei Liu, Zhenzhong Yang, Rong Huang, Jing Xie, Yang Tian, Di Li*, In-Situ Plasmonic Tracking Oxygen Evolution Reveals Multistage Oxygen Diffusion and Accumulating Inhibition, Nature Commun. 2021, 2164
6. Lele Sun, Yanjing Gao, Yan Xu, Jie Chao, Huajie Liu, Lianhui Wang, Di Li*, Chunhai Fan, Real-Time Imaging of Single-Molecule Enzyme Cascade Using a DNA Origami Raft, J. Am. Chem. Soc. 2017, 139, 17525-17532
7. Weiwei Qin, Tianhuan Peng, Yanjing Gao, Fei Wang, Xiaocai Hu, Kun Wang, Jiye Shi, Di Li*, Jicun Ren, Chunhai Fan, Catalysis-Driven Self-Thermophoresis of Janus Plasmonic Nanomotors, Angew. Chem. Int. Ed. 2017, 56, 515-518
8. Kun Li, Kun Wang, Weiwei Qin, Suhui Deng, Di Li*; Jiye Shi, Qing Huang, Chunhai Fan, DNA-Directed Assembly of Gold Nanohalo for Quantitative Plasmonic Imaging of Single-Particle Catalysis, J. Am. Chem. Soc. 2015, 137, 4292-4295
9. Kun Li, Weiwei Qin, Fan Li, Xinchun Zhao, Bowei Jiang, KunWang, Suhui Deng, Chunhai Fan*, Di Li*, Nanoplasmonic Imaging of Latent Fingerprints and Identification of Cocaine, Angew. Chem. Int. Ed. 2013, 52, 11542-11545
10.Xiaozue Zheng, Qing Liu, Chao Jing, Yang Li, Di Li*, Weijie Luo, Yanqin Wen, Yao He, Qing Huang, Yi-Tao Long, Chunhai Fan*, Catalytic Gold Nanoparticles for Nanoplasmonic Detection of DNA Hybridization, Angew. Chem. Int. Ed. 2011, 50, 11994-11998

*以上信息由高级会员个人更新和维护。