宋钦华

男， 中国科学技术大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

1983.09-1986.06，湖北襄阳师范专科学校/化学系，专科学生
1986.07-1989.08，湖北襄阳第七中学，教师
1989.09-1992.05，航天部第四研究院，硕士研究生
1992.06-1994.08，航天工业总公司第42研究所，工程师
1994.09-1997.06，中国科学院上海原子核研究所，博士研究生
1997.07-1999.08，中国科学技术大学，博士后
1999.09-2005.11，中国科学技术大学化学系，副教授
2005.12-至今，中国科学技术大学化学系，教授
1999.10-2000.2，日本大阪大学，访问学者
2002.10-2003.09，新竹国立清华大学化学系，博士后
2006.10-2007.05，美国俄亥俄州立大学，访问学者

研究领域和兴趣

有机光化学

主要业绩

1.DNA光解酶的作用机理研究：设计合成多种光解酶-底物模型，研究光诱导电子转移反应及二聚体裂解过程，阐明了DNA光解酶的作用机理，获得的嘧啶二聚体阴离子自由基裂解的活化能（1-2kJ/mol），平息了多年来关于DNA光复活过程活化能值的争论；
2.分子内电荷转移反应及其应用：系统研究了三芳硼结构与其分子内电荷转移（ICT）性质的关系，建立了结构与性质的热力学关系。这一关系对太阳电池染料分子设计、荧光分子探针设计具有很好的指导意义；
3.发展了一系列光气及其替代品的高选择性高灵敏化学传感器，检测限（0.7 nM）、选择性均处于国际领先，并且，制备方便快捷的气相检测的试纸，显色明显、灵敏度高，可望用于反恐处突及民防安全生产中。

代表成果

论文：
1. Hei XM, Song QH,* Li XB, Tang WJ, Wang HB, Guo QX, Origin of a large temperature dependence of regioselectivity observed for [2+2] photocycloaddition (Paterno-Buchi reaction) of 1,3-dimethylthymine with benzophenone and its derivatives: Conformational property of the intermediary triplet 1,4-diradicals, J. Org. Chem. 2005, 70, 2522-2527.
2. Qin-Hua Song, Wen-Jian Tang, Xue-Bao Ji, Hong-Bo Wang, Qing-Xiang Guo, Do Photolyases Need To Provide Considerable Activation Energy for the Splitting of Cyclobutane Pyrimidine Dimer Radical Anions? Chem. Eur. J. 2007, 13, 7762-7770/DOI: 10.1002/chem.200700251
3. Mao Mao, Ming-Guang Ren, Qin-Hua Song,* Thermodynamics and conformations in the formation of the excited states and their interconversions for twisted donor-substituted tridurylboranes, Chem. Eur. J. 2012, 18, 15512-15522. DOI: 10.1002/chem.201201719.
4. Ming-Guang Ren, Mao Mao and Qin-Hua Song,* The equilibria and conversions between three excited states: the LE state and two charge transfer states, in twisted pyrene-substituted tridurylboranes, Chem. Commun. 2012, 48, 2970–2972. DOI: 10.1039/c2cc17663g.
5. Xiu-Ling Liu, Jian-Bo Wang, Yao Tong, and Qin-Hua Song,* Regioselectivity, and competition of Paternò-Büchi reaction with triplet-triplet energy transfer between triplet benzophenones and pyrimidines: Control by triplet energy levels, Chem. Eur. J. 2013, 19, 13216-13223. DOI: 10.1002/chem.201300958.
6. Mao Mao, and Qin-Hua Song,* The structure-property relationships of D-p-A Bodipy dyes for dye-sensitized solar cells, Chem. Rec. 2016, 16, 719-733. DOI: tcr.201500251.
7. Xiu-Ling Liu, Xiao-Jiao Du, Chun-Guang Dai, Qin-Hua Song,* Ratiometric two-photon fluorescent probes for mitochondrial hydrogen sulfide in living cells, J. Org. Chem. 2014, 79, 9481-9489. DOI: 10.1021/jo5014838.
8. Yuan-Chao Cai, Chen Li and Qin-Hua Song,* Selective and visual detection of a nerve agent mimic by phosphorylation and protonation of quinolin oximes, J. Mater. Chem. C 2017, 5, 7337-7343. DOI: 10.1039/C7TC02617J.
9. Yuan-Chao Cai, Chen Li, and Qin-Hua Song,* Fluorescent chemosensors with varying degrees of intramolecular charge transfer for detection of a nerve agent mimic in solutions and in vapor, ACS Sens. 2017, 2(6), 834–841. DOI: 10.1021/acssensors.7b00205.
10. M.-J. Xue, X.-Z. Wei, W. Feng, Z.-F. Xing, S.-L. Liu, Q.-H. Song, Sensitive and selective detections of mustard gas and its analogues by 4-mercaptocoumarins as fluorescent chemosensors in both solutions and gas phase, Journal of Hazardous Materials 2021, 416, 125789.
专利：
1. 宋钦华; 冯伟. 一种芥子气荧光探针及试剂盒、检测试纸及其制备方法; ZL2020101369555，专利号：CN111253307B
2. 宋钦华; 韦秀芝; 王木士. 神经毒剂模拟物的荧光探针及试纸及其制备方法; ZL2020101693008，专利号：CN111269251B.
3. 宋钦华; 王少林， 一种快速检出光气的比色、荧光探针及其合成方法;ZL2018109828148, 专利号：CN108774227B
4. 宋钦华; 韦秀芝, 一种快速检出光气的比色荧光探针化合物及其合成方法; ZL2019101647219, 专利号： CN109776591B

*以上信息由高级会员个人更新和维护。