张松柏

男， 湖南文理学院化学与材料工程学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

2000.09-2004.07，湖南文理学院化学化工学院，本科学生
2004.09-2009.07，湖南大学化学化工学院，化学/生物传感与计量学国家重点实验室，硕博连读
2009.09-2011.06，杭州电子科技大学电子信息学院，讲师
2011.07-至今 湖南文理学院化学与材料工程学院，教授
2015.04-2017.04，中南大学化学博士后流动站，博士后，导师：国家杰青周飞艨教授
2017.04-2017.09，福州大学化学学院，访问学者，导师：青年千人吴再生教授
2017.09-2018.09，美国伊利诺伊大学香槟分校，访问学者，导师：国际著名科学家Yi Lu教授

研究领域和兴趣

生化分析及生物传感

主要业绩

主要从事无机纳米材料与核酸纳米材料的制备与应用、生化分析新方法、传感器构建新技术以及细胞成像等领域的基础研究以及在环境监测、食品安全、重大疾病诊断与治疗等方面的应用研究。主持国家自然科学基金、中国博士后基金面上项目、湖南省自然科学基金、湖南省教育厅项目、化学生物传感与计量学国家重点实验室开放基金等项目10余项，并在相关研究领域取得了一定的成果，目前已在“Journal of the American Chemical Society”、“Angewandte Chemie International Edition”、“Nucleic Acids Research”、 “Analytical Chemistry”“Chemical Communication”、“Biosensors and Bioelectronics”等国际高水平期刊上以第一作者及参与研究发表论文60余篇，其中SCI收录53篇（包括一区Top期刊论文21篇），EI论文4篇，授权发明专利1项，相关科研成果以第1单位排名第1获得湖南省自然科学三等奖1项。

代表成果

[1] Songbai Zhang, Yunxia Luan*, Mengyi Xiong, Jingjing Zhang, Ryan Lake, Yi Lu*. DNAzyme amplified aptasensing platform for ochratoxin A detection using a personal glucose meter. ACS Applied Materials Interfaces, 13: 9472-9481 (2021). 10.1021/acsami.0c20417
[2] Chang Xue#, Songbai Zhang#, Xin Yu, Shuyao Hu, Yi Lu*, Zai-Sheng Wu*. Periodically ordered, nuclease-resistant DNA nanowires decorated with cell-specific aptamers as selective theranostic agents. Angew. Chem. Int. Ed. 132(40): 17693-17700 (2020). 10.1002/anie.202004805 (#共同第一作者，指导研究生)
[3] Changhe Ouyang#, Songbai Zhang#, Chang Xue#, Xin Yu, Huo Xu, Zhenmeng Wang, Yi Lu*, Zai-Sheng Wu*. Precision-guided missile-like DNA nanostructure containing warhead and guidance control for aptamer-based targeted drug delivery into cancer cells in vitro and in vivo. Journal of the American Chemical Society, 142(3): 1265-1277 (2020). 10.1021/jacs.9b09782 (#共同第一作者，指导研究生)
[4] Chang Xue#, Songbai Zhang#, Congcong Li, Xin Yu, Changhe Ouyang, Yi Lu*, Zai-Sheng Wu*. Y-Shaped Backbone-Rigidified Triangular DNA Scaffold-Directed Stepwise Movement of a DNAzyme Walker for Sensitive MicroRNA Imaging within Living Cells. Analytical Chemistry, 91(24): 15678-15685 (2019). 10.1021/acs.analchem.9b03784 (#共同第一作者，指导研究生)
[5] Jifeng Yang, Min He, Tengfei Wu, Aiping Hao, Songbai Zhang*, Yuandao Chen, Shibiao Zhou, Liying Zhen, Rong Wang, Zilin Yuan, Lin Deng*. Sulfadiazine oxidation by permanganate: Kinetics, mechanistic investigation and toxicity evaluation. Chemical Engineering Journal, 349: 56-65 (2018). 10.1016/j.cej.2018.05.018
[6] Songbai Zhang*, Xia Hu, Xiaohui Yang, Qinli Sun, Xiaolin Xu, Xuewen Liu, Guangyu Shen, Jilin Lu, Guoli Shen and Ruqin Yu. Background eliminated signal-on electrochemical aptasensing platform for highly sensitive detection of protein, Biosensors and Bioelectronics, 66, 363–369 (2015). 10.1016/j.bios.2014.11.044
[7] Songbai Zhang, Zaisheng Wu*, Guoli Shen*, and Ruqin Yu. Blank peak current-suppressed electrochemical aptameric sensing platform for highly sensitive signal-on detection of small molecule. Nucleic Acids Research, 38: e185 (2010). 10.1093/nar/gkq728
[8] Songbai Zhang, ZaiSheng Wu*, Liping Qiu, Hui Zhou, Guoli Shen* and Ruqin Yu. G-quadruplex signaling probe for highly sensitive DNA detection. Chemical Communications, 46: 3381-3383 (2010). 10.1039/b926646a
[9] Songbai Zhang, Zaisheng Wu, Guoli Shen*, and Ruqin Yu. A label-free strategy for SNP detection with high fidelity and sensitivity based on ligation-rolling circle amplification and intercalating of methyene blue, Biosensors and Bioelectronics, 24: 3201-3207 (2009). 10.1016/j.bios.2009.03.012
[10] Songbai Zhang, Fan Zheng, Zaisheng Wu, Guoli Shen*, and Ruqin Yu. Highly sensitive electrochemical detection of immunospecies based on combination of Fc label and PPD film/gold nanoparticle amplification, Biosensors and Bioelectronics, 24: 129-135 (2008). 10.1016/j.bios.2008.03.017

*以上信息由高级会员个人更新和维护。