陈建军

男， 兰州大学天然产物化学全国重点实验室， 教授/研究员/教授级高工或同等级别

学习/工作经历

2000-2004 忻州师范学院，理学学士
2004-2009 兰州大学，理学博士
2009-2013 兰州大学功能有机分子化学国家重点实验室，讲师
2014-至今 兰州大学功能有机分子化学国家重点实验室，副教授
2016-2017 Scripps 研究所，访问学者

研究领域和兴趣

天然有机化学

主要业绩

主要从事药用植物中新颖结构天然产物的高效发现、结构修饰和生物活性研究。主持国家自然科学基金项目4项（已结题2项）甘肃省自然科学基金1项。完成国家重点基础研究发展计划（973计划）项目2项，国家科技支撑计划项目1项。从二十多种药用植物及其内生真菌中挖掘了三百余种结构新颖的天然小分子化合物，发现二十余种有意义的药物先导化合物。在国际著名的SCI引用期刊上发表论文52篇，获得国家发明专利3项。担任Natural Products and Bioprospecting杂志的青年编委以及Organic Letters，Journal of Natural Products，Journal of Organic Chemistry 等多个国际SCI杂志的审稿人。荣获甘肃省技术标兵，甘肃省青年教师成才奖等奖励。

代表成果

1、Zeng, J.; Zhang, D. B.; Zhou, P. P.; Zhang, Q. L.; Zhao, L.; Chen, J. J.*; Gao, K. * “Rauvomines A and B, Two Monoterpenoid Indole Alkaloids from Rauvolfia vomitoria”. Org. Lett. 2017, 19 (15), 3998−4001. doi.org/10.1021/acs.orglett.7b01723.
2、Yan, X.#; Chen, J. J.#; Adhikari, A.; Yang, D.; Crnovcic, I.; Wang, N.; Chang, C. Y.; Rader, C.; Shen, B.* “Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne”. Org. Lett. 2017, 19 (22), 6192−6195. (# contributed equally) doi.org/10.1021/acs.orglett.7b03120.
3、Yan, X.#; Chen, J. J.#; Adhikari, A.; Teijaro, C. N. Ge, H.; Crnovcic, I.; Chang, C. Y.; Annaval, T.; Yang, D.; Rader, C.; Shen B. * “Comparative Studies of the Biosynthetic Gene Clusters for Anthraquinone-Fused Enediynes Shedding Light into the Tailoring Steps of Tiancimycin Biosynthesis”. Org. Lett. 2018, 20, 5918−5921. (# contributed equally) doi.org/10.1021/acs.orglett.8b02584.
4、Yang, H. Y; Yao, W.; Huang, P. Z.; Xu, H.; Ma, Q.; Chen, X.; JChen, J. J.*; Gao, K.* "Euphohelides A–C, ent-Abietane-Type Norditerpene Lactones from Euphorbia helioscopia and Their Anti-Inflammatory Activities". J. Nat. Prod. 2023, 86, ASAP, doi.org/10.1021/acs.jnatprod.3c00041.
5、Chen, J. J.; Bai, W.; Lu, Y. B.; Feng, Z. Y.; Gao, K.*; Yue, J. M.* “Quassinoids with Inhibitory Activities against Plant Fungal Pathogens from Picrasma javanica”. J. Nat. Prod. 2021, 84(8), 2111−2120. doi.org/10.1021/acs.jnatprod.1c00096.
6、Li, H. Y.; Peng, X.; Jin, X.; Wei,W. J.; Ma, K. L.; Li, Y.; Chen, J. J.*; Gao, K.* “Labdane-Type Diterpenoids from Leonurus japonicus and Their Plant-Growth Regulatory Activity”. J. Nat. Prod. 2019, 82(9), 2568−2579. doi.org/10.1021/acs.jnatprod.9b00422.
7、Bai, W; Yang, H. Y.; Jiao, X. Z.; Feng, K. N.; Chen, J. J. *; Gao, K.* “Structurally Diverse Highly Oxygenated Triterpenoids from the Roots of Ailanthus altissima and Their Cytotoxicity”. J. Nat. Prod. 2018, 81(8), 1777−1785. doi.org/10.1021/acs.jnatprod.8b00208.
8、Chen, J. J.#; Rateb, M. E. #; Love, M. S.; Xu, Z.; Yang, D.; Zhu, X.; Huang, Y.; Zhao, L. X.; Jiang, Y.; Duan, Y.; McNamara, C. W., Shen B. * “Herbicidins from Streptomyces sp. CB01388 Showing Anti-Cryptosporidium Activity”. J. Nat. Prod. 2018, 81(4), 791−797. (# contributed equally) doi.org/10.1021/acs.jnatprod.7b00850.
9、Gobu, F. R.; Chen, J. J.*; Zeng, J.; Wei, W. J.; Wang, W. F.; Lin, C. J.; Gao, K.* “Isolation, Structure Elucidition, and Immunosuppressive Activity of Diterpenoids from Ligularia f ischeri”. J. Nat. Prod. 2017, 80(8), 2263−2268. doi.org/10.1021/acs.jnatprod.7b00198.
10、Chen, J. J., Chen, C. J.; Yao, X. J.;Jin, X. J.; Gao K. * “Eremophilane-Type Sesquiterpenoids with Diverse Skeletons from Ligularia sagitta”. J. Nat. Prod. 2014, 77(6), 1329−1335. doi.org/10.1021/np5003302.

*以上信息由高级会员个人更新和维护。