刘培念

男， 中国药科大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

2024-至今，中国药科大学，教授，博士生导师
2019，获国家杰出青年科学基金资助
2015 – 2023，华东理工大学，上海市“东方学者”特聘教授
2016（8-10月），劳伦斯伯克利国家实验室和加州大学伯克利分校，高级访问学者
2013 – 2015，香港科技大学物理系和加州大学欧文分校，高级研究学者
2013 – 2023，华东理工大学，化学与分子工程学院精细化工研究所，博士生导师
2012 – 2023，华东理工大学，化学与分子工程学院精细化工研究所，教授
2008 – 2012，华东理工大学，化学与分子工程学院精细化工研究所，副教授
2004 – 2008，香港科技大学化学系和香港理工大学应用生物与化学科技系，博士后
2001 – 2004，兰州大学，有机化学，博士，导师：涂永强 院士
1998 – 2001，兰州大学，有机化学，硕士，导师：陈耀祖 院士
1994 – 1998，兰州大学，有机化学，学士，国家级化学专业基地班

研究领域和兴趣

药物化学、表面合成化学

主要业绩

主要研究方向是药物化学和表面合成化学，致力于：1）进行肿瘤靶点相关的小分子药物设计、合成与活性评价，并基于所设计的新型有机热释电材料，开发出肿瘤的热释电动力/免疫协同疗法；2）发展各种表面合成反应的新策略和新方法，在单分子水平研究有机反应机理，并进一步实现低维有机纳米材料的构筑和性质研究。截至2024/12，已发表SCI收录论文120余篇，从2010年独立建立课题组至今以通讯作者在Acc. Chem. Res.、 Nat. Commun.（3篇）、J. Am. Chem. Soc.（12篇）、Angew. Chem. Int. Ed.（6篇）、Adv. Mater.、Sci. Adv. 等中科院二区以上期刊发表SCI论文80余篇。已主持国家自然科学基金项目8项和省部级项目8项，参与国家自然科学基金重大项目1项和创新研究群体项目1项。

代表成果

1. Y. Wang, W.-W. Gong, Y. Zhao, G.-Y. Xing, L.-X.Kang, F. Sha, Z.-Y. Huang, J.-W. Liu, Y.-J. Han, P. Li, D.-Y. Li,* P.-N. Liu*. Two-DimensionalNonbenzenoid Heteroacene Crystals Synthesized via In-Situ Embedding of LadderBipyrazinylenes on Au(111). Angew. Chem. Int. Ed. 2024,63, e202318142
2. J.-W. Liu, Y. Wang, L.-X. Kang, Y.Zhao, G.-Y. Xing, Z.-Y. Huang, Y.-C. Zhu, D.-Y. Li*, P.-N. Liu*. Two-Dimensional Crystal Transition from Radialene toCumulene on Ag(111) via Retro-[2+1] Cycloaddition. J. Am. Chem. Soc. 2023, 145, 13048.
3. G. Zhu, Y. Jiang, Y. Wang, B.-X.Wang, Y. Zheng, Y. Liu, L.-X. Kang, Z. Li, D. Guan, Y. Li, H.Zheng, C. Liu, J. Jia, T. Lin, P.-N.Liu*, D.-Y. Li*, S. Wang*. Collective Quantum Magnetism inNitrogen-Doped Nanographenes, J. Am. Chem. Soc. 2023. 145, 7136.
4. D.-Y. Li,* Y. Wang, X.-Y. Hou,Y.-T. Ren, L.-X. Kang, F.-H. Xue, Y.-C. Zhu, J.-W. Liu, M. Liu*, X.-Q. Shi*, X.Qiu*, P.-N. Liu*. On-SurfaceSynthesis of [3]Radialenes via [1+1+1] Cycloaddition”. Angew. Chem. Int. Ed. 2022,61, e202117714.
5. D.-Y. Li, X. Qiu, S.-W. Li, Y.-T.Ren, Y.-C. Zhu, C.-H. Shu, X.-Y. Hou, M. Liu*, X.-Q. Shi*, X. Qiu*, P.-N. Liu*. Ladder PhenylenesSynthesized on Au(111) Surface via Selective [2+2] Cycloaddition, J. Am. Chem. Soc. 2021, 143, 12955.
6. D.-Y. Li, Y.-C. Zhu, S.-W. Li,C.-H. Shu, P.-N. Liu*. Post-Functionalization of Supramolecular Polymers onSurface and the Chiral Assembly-Induced Enantioselective Reaction, Angew. Chem. Int. Ed. 2021, 60, 11370.
7. C.-H. Shu, Y. He, R.-X. Zhang,J.-L. Chen, A. Wang, P.-N. Liu*.Atomic-Scale Visualization of Stepwise Growth Mechanism of Metal-Alkynyl Networkson Surfaces, J. Am. Chem. Soc. 2020, 142, 39, 16579.
8. D.-Y. Li, S.-W. Li,Y.-L. Xie, X. Hua, Y.-T. Long, A. Wang, P.-N. Liu*. On-surface synthesis ofplanar dendrimers via divergent cross-coupling reaction, Nat. Commun., 2019, 10, 2414.
9. X. Li, X. Ma, Z. Wang, P.-N.Liu*, L. Zhang*. Bifunctional Phosphine Ligand Enabled Gold‐CatalyzedAlkynamide Cycloisomerization: Access to Electron‐Rich 2‐Aminofurans and TheirDiels–Alder Adducts, Angew. Chem. Int.Ed., 2019, 58, 17180.
10. C.-H.Shu, M.-X. Liu, Z.-Q. Zha, J.-L. Pan,S.-Z. Zhang, Y.-L. Xie, J.-L.Chen, D.-W. Yuan, X.-H. Qiu*, P.-N. Liu*. On-surface synthesis ofpoly(p-phenylene ethynylene) molecular wires via in situ formation ofcarbon-carbon triple bond, Nat. Commun.,2018, 9, 2322.
11. G. Kuang†, S.-Z. Chen†, L.Yan, K.-Q. Chen*, X. Shang, P.-N. Liu*,N. Lin*. Negative Differential Conductance in Polyporphyrin Oligomers withNonlinear Backbones, J. Am. Chem. Soc., 2018, 140, 570.
12. L. Yan,* B.Xia, Q. Zhang, G. Kuang, H. Xu, J. Liu, P.-N. Liu*, N. Lin*. Stabilizing andOrganizing Bi3Cu4 and Bi7Cu12 Nanoclusters in Two-Dimensional Metal-OrganicNetworks, Angew. Chem. Int. Ed., 2018,57, 4617.
13. D.-Y. Li, H.-J. Chen, P.-N.Liu*. Tunable Cascade Reactions of Alkynols with Alkynes under CombinedSc(OTf)3 and Rhodium Catalysis, Angew.Chem. Int. Ed., 2016, 55, 373.
14. G. Kuang, S.-Z. Chen, W. Wang, T. Lin, K. Chen, X. Shang, P.-N. Liu,* N. Lin*. Resonant Charge Transport in Conjugated Molecular Wiresbeyond 10 nm Range, J. Am. Chem. Soc.,2016, 138, 11140.
15. L. Dong, P.-N. Liu*,N. Lin*. Surface-Activated Coupling Reactions Confined on a Surface, Acc. Chem. Res., 2015, 48, 2765.
16. T. Lin, X.-S. Shang, J. Adisoejoso, P.-N. Liu*, N. Lin*. Steering On-Surface Polymerization withMetal-Directed Template, J. Am. Chem.Soc., 2013, 135, 3576.
17. J. Adisoejoso, Y. Li, J. Liu, P.-N. Liu*, N. Lin*. Two-Dimensional Metallo-SupramolecularPolymerization: Towards Size Controlled Multi-strand Polymers, J. Am. Chem. Soc., 2012, 134, 18526.
18. J. Liu, T. Lin, Z. Shi, F. Xia, P.-N. Liu*, N. Lin*. Structural Transformation of Two-DimensionalMetal-Organic Coordination Networks Driven by Intrinsic In-Plane Compression, J. Am. Chem. Soc., 2011, 133, 18760.
19. Z. Shi, J. Liu, T. Lin, F. Xia, P.-N. Liu*, N. Lin*. Thermodynamics and Selectivity ofTwo-dimensional Metallo-Supramolecular Self-assembly Resolved at MolecularScale, J. Am. Chem. Soc., 2011, 133, 6150.
20. W. Wang, S. Wang, X. Li, J.-P.Collin, J. Liu, P.-N. Liu*, N. Lin*.Probing Electronic Superexchange Coupling at Isolated Poly-p-phenyleneMolecules, J. Am. Chem. Soc., 2010, 132, 8774.

*以上信息由高级会员个人更新和维护。