许志刚

男， 西南大学材料与能源学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

2008.09-2013.06 兰州大学 化学化工学院 博士
2013.07-2015.07 新加坡南洋理工大学 化学与生物工程学院 博士后
2015.07-2021.06 西南大学 材料与能源学院 副教授，硕导
2021.06-2024.05 西南大学 材料与能源学院 教授，硕导
2024.06-至今 西南大学 材料与能源学院 教授，博导

研究领域和兴趣

医用化学材料；生物医用高分子；纳米药物递送系统

主要业绩

长期专注于功能高分子纳米药物递送系统的可控构筑及其抗肿瘤应用研究，先后开发了一系列刺激响应型高分子纳米药物，实现肿瘤微环境的化学调控与肿瘤治疗增效。先后获国家重点研发计划课题、国家自然科学基金、四川省科技厅重点研发项目、重庆英才·青年拔尖人才项目和重庆市留学人员回国创业创新支持计划等资助。发表Chemical Society Reviews、Advanced Materials、Advanced Functional Materials、ACS Nano、Advanced Science等论文60余篇，授权国家发明专利15项。获得2014年甘肃高校科技进步奖一等奖（排名第三）。

代表成果

[1] Xianbin Ma, Shujin Li, Yuantong Liu, Tian Zhang, Peng Xue, Yuejun Kang, Zhi-Jun Sun* and Zhigang Xu*, Bioengineered Nanogels for Cancer Immunotherapy, Chemical Society Reviews, 2022, 51, 5136.
[2] Wen Su, Wei Qiu, Shu-Jin Li, Shuo Wang, Jun Xie, Qi-Chao Yang, Jiming Xu, Junjie Zhang*, Zhigang Xu* and Zhi-Jun Sun*, Dual-Responsive STAT3 Inhibitor Nanoprodrug Combined with Oncolytic Virus Elicits Synergistic Antitumor Immune Responses by Igniting Pyroptosis, Advanced Materials, 2023, 35, 2209379.
[3] Xianbin Ma, Meng-Jie Zhang, Jingting Wang, Tian Zhang, Peng Xue, Yuejun Kang, Zhi-Jun Sun* and Zhigang Xu*, Emerging Biomaterials Imaging Antitumor Immune Response, Advanced Materials, 2022, 34, 2204034
[4] Shanshan Zhang, Mengjie Ye, Linlin Han, Hengbo Zhang, Qihan Wang, Menglin Zhang, Fanpeng Ran*, Xiaoxiao Shi*, and Zhigang Xu*，Near-Infrared-Triggered Photoresponsive Nanobombs Overcome Tumor Immunosuppression through Coordinated Pyroptosis Activation and Mitophagy Blockade, ACS Nano, 2025, 19, 40184−40197
[5] Mengjie Ye, Junfeng Hu, Linlin Han, Hengbo Zhang, Peng Xue, Yuejun Kang, Shuang Bai*, Zhigang Xu*, Neighboring Effect-initiated Supramolecular Nanocomplex with Sequential Infiltration as Irreversible Apoptosis Inducer for Synergetic Chemo immunotherapy, Advanced Science, 2024, 11, 2402809.
[6] Yuan-Yuan Wang, Jingting Wang, Shuo Wang, Qi-Chao Yang, An Song, Meng-Jie Zhang, Wen-Da Wang, Yuan-Tong Liu, Junjie Zhang, Wei-Ming Wang*, Zhigang Xu*, Zhi-Jun Sun*, Dual-Responsive Epigenetic Inhibitor Nanoprodrug Combined With Oncolytic Virus Synergistically Boost Cancer Immunotherapy By Igniting Gasdermin E-Mediated Pyroptosis, ACS Nano, 2024, 18, 20167–20180
[7] Meng-Jie Zhang, Yuan-Yuan Wang, Lin-Lin Han, Xin-Yang Liu, Yun-Yun Xie, Zhigang Xu*, Zhi-Jun Sun*. Biomaterials Elicit Pyroptosis Enhancing Cancer Immunotherapy, Advanced Functional Materials, 2024, 34, 2311362
[8] Jiming Xu, Wei Qiu, Mengyun Liang, Mengjie Ye, Junfeng Hu, Xianbin Ma, Xiaoxiao Shi, Peng Xue, Yuejun Kang, Bo Xiao*, Zhigang Xu*, Dual-Stimulus Phototherapeutic Nanogel for Triggering Pyroptosis to Promote Cancer Immunotherapy. Journal of Controlled Release, 2023, 358, 219.

*以上信息由高级会员个人更新和维护。