刘海洋

男， 华南理工大学化学与化工学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

1980.09-1984.06：江西大学化学系无机化学专业读本科, 获理学学士学位
1984.07-1986.08: 江西冶金学院基础部化学教研室，助教
1986.09-1989.06: 中山大学化学系无机化学专业硕士研究生，获理学硕士学位
1989.07-1994.08：赣南师范学院化学系，讲师
1994.09-1997.06：中山大学化学系无机化学专业硕士研究生，获理学博士学位
1997.07-至今：华南理工大学教师（期间：2000.05评为副教授；2009.12评为教授）
1999.05-2000.04：台湾淡江大学博士后；
2001.04-2002.10，2003.05-2007.07：香港科技大学博士后、访问学者

研究领域和兴趣

过渡金属配位化学与化学生物学

主要业绩

目前，主持并完成国家自然科学基金5项，企业委托研究项目4项，获广东省科技进步三等奖一项。发表学术论文100多篇。
发现了具有氧原子转移活性的[LMn≡O]配合物(J. Am. Chem. Soc. 2009，131(36):12890），为揭开锰催化氧化与光合作用产氧机制提供了新的视角。改进了二氧化氯消毒剂生产工艺，使分子态二氧化氯消毒剂有效期达到一年以上（粤卫消证字【2019】-12第0029号）。

代表成果

代表性论文：
1. Cen, JH; Xie, QH; Guo, GH; Xu, SY; Liu, ZY; Liao, YH*; Zhong, XP*; Liu, HY*. Construction of 5-Fluorouracil and Gallium Corrole Conjugates for Enhanced Photodynamic Therapy. JOURNAL OF MEDICINAL CHEMISTRY, 2024, 67(11): 9054-9068. DOI10.1021/acs.jmedchem.4c00249.
2. Liu, ZW; Yang, G; Xu, SY; Xie, WY; Yao, YF; Xiao, XY*; Si, LP*; Liu, HY*. First Application of Non-Metallic A2B Type Silicon Corrole Complexes in Electrocatalytic Hydrogen Evolution. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY. 2024, 27(15): e202300790. DOI10.1002/ejic.202300790.
3. Yan, QW; Wu, LW; Liu, ZW; Chen, F; Ling, C; Liu, HY*; Xiao, XY*; Si, LP*. First application of antimony(III) corrole for electrocatalytic hydrogen evolution. GREEN CHEMISTRY. 2024, 26(8): 4574-4581.DOI10.1039/d3gc04884e.
4. Xie, WY; Ling, C; Huang, ZY; Chen, WC; He, SF; Si, LP*; Liu, HY*. Metalloporphyrin doped rice husk-based biomass porous carbon materials as high performance electrocatalyst for oxygen reduction reaction in Zn-Air battery. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY. 2024. 51: 857-868. DOI10.1016/j.ijhydene.2023.07.088.
5. Cen, JH; Xie, QH; Guo, GH; Gao, LJ; Liao, YH*; Zhong, XP*; Liu, HY*. Azide-modified corrole phosphorus complexes for endoplasmic reticulum-targeted fluorescence bioimaging and effective cancer photodynamic therapy. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2024. 265: 116120. DOI10.1016/j.ejmech.2023.116102.
6. Yang, G; Ullah, Z*; Yang, W; Kwon, HW; Liang, ZX; Zhan, X*; Yuan, GQ*; Liu, HY.* Substituent Effect on Ligand-Centered Electrocatalytic Hydrogen Evolution of Phosphorus Corroles. CHEMSUSCHEM. 2023, 16(10): e202300211. DOI10.1002/cssc.202300211.
7. Yang, W; Yang, G; Li, MY; Liu, ZY; Liao, YH*; Liu, HY*. Photodynamic antitumor activity of Gallium(III) and Phosphorus(V) complexes of trimethoxyl A2B triaryl corrole. BIOORGANIC CHEMISTRY. 2022, 129: 106177. DOI10.1016/j.bioorg.2022.106177.
8. Tang, Y; Li, MN; Huang, ZY; Liu, HY*; Xiao, XY*; Zhang, SQ. Synthesis of Metal Xanthene-Bridged Bis-corroles and their Catalytic Activity in Aerobic Baeyer-Villiger Oxidation Reaction. ASIAN JOURNAL OF ORGANIC CHEMISTRY. 2022, 11(9): e202200349. DOI10.1002/ajoc.202200349.
9. Liu, LG; Sun, YM; Liu, ZY; Liao, YH*; Zeng, L; Ye, Y; Liu, HY*. Halogenated Gallium Corroles: DNA Interaction and Photodynamic Antitumor Activity；INORGANIC CHEMISTRY，2021，60(4)：2234-2245. DOI:10.1021/acs.inorgchem.0c03016.
10. Yang, S; Xiong, MF; Tian, WQ; Zhang, H; Xiao, XY; Liu, HY*; Chang, CK*. Construction of C-O bond via cross-dehydrogenative coupling of sp [3] C-H bond with phenols catalyzed by copper porphyrin. TETRAHEDRON, 2020, 76(45): 131569. DOI: 10.1016/j.tet.2020.131569.
11. Huang, LT; Ali, A; Wang, HH; Cheng, F; Liu, HY*. Catalytic oxidation of alkene by cobalt corroles. JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2017, 426: 213-222. DOI: 10.1016/j.molcata.2016.11.019.
12. Liu, HY*; Mahmood, MHR; Qiu, SX; Chang, CK. Recent developments in manganese corrole chemistry. COORDINATION CHEMISTRY REVIEWS, 2013, 257(7-8): 1306-1333. DOI: 10.1016/j.ccr.2012.12.017.
13. Liu, HY*; Yam, F; Xie, YT; Li, XY; Chang, CK*. A Bulky Bis-Pocket Manganese(V)-Oxo Corrole Complex: Observation of Oxygen Atom Transfer between Triply Bonded Mn-V O and Alkene. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131(36): 12890-+. DOI: 10.1021/ja905153r.
14. Liu, HY; Lai, TS; Yeung, LL; Chang, CK*. First synthesis of perfluorinated corrole and its Mn=O complex. ORGANIC LETTERS, 2003, 5(5): 617-620. DOI: 10.1021/ol027111i.
15. Liu, HY; Huang, JW; Tian, X; Jiao, XD; Luo, GT; Ji, LN*. Chiral linear assembly of amino acid bridged dimeric porphyrin hosts. CHEMICAL COMMUNICATIONS, 1997, 16: 1575-1576. DOI: 10.1039/a702876h.

发明专利：
1. 刘海洋;杨武;李梦媛；一种不同空间结构的磷咔咯化合物及其制备方法与应用；2023，：ZL 2022 1 0232860.2.

*以上信息由高级会员个人更新和维护。