付颖

女， 东北农业大学文理学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

1992.09-1996.07，黑龙江大学，应用化学专业，本科学生
1999.09-2002.07，东北农业大学，农药学专业，研究生，硕士学位
2003.09-2009.04，哈尔滨工业大学，化学工程与技术专业，研究生，博士学位
2008.03-2008.09，University of California, San Diego，访问学者
2009.06-2011.09，东北农业大学作物学流动站，博士后
2012.07-2013.07，University of California, San Diego，访问学者
1996.7-2001.8 东北农业大学基础部 助教
2001.9-2006.8 东北农业大学理学院 讲师
2006.9-2011.8东北农业大学理学院 副教授
2011.9 至今 东北农业大学文理学院 教授

研究领域和兴趣

农业化学

主要业绩

主要从事新农药创制过程中，在国家自然基金等课题的资助下利用计算机辅助药物分子设计和高通量筛选技术，获得了新型HPPD抑制剂的骨架结构，开展了候选药物的研究。基于此，本项目针对玉米田中的抗性杂草及除草剂使用中的安全性问题，提出以HPPD为除草剂作用靶标酶，通过天然产物的亚结构重组，嫁接已商品化HPPD抑制类除草剂药效团，利用分子对接和分子动力学模拟设计全新的HPPD抑制剂骨架结构，以期获得适用于玉米田的HPPD抑制类除草剂候选化合物。本项研究为我国自主开发高效、安全、广谱的HPPD抑制剂提供前期基础理论研究，并为解决杂草抗性问题提供有效解决途径。
具有在国内外一流大学的科研经历，科研能力强。主持完成国家自然科学基金等14项课题；在Journal of Agricultural and Food Chemistry等国际期刊上发表SCI收录科研论文100余篇；被引用500余次，获得黑龙江省科技奖二等奖两项，三等奖一项，省农业科技一等奖等多项奖励，个人先后获得省青年科技奖和哈尔滨市青年科技奖；获得授权发明专利5项。担任中国化工学会农药分委会委员，担任Industrial Crops & Products等多个著名SCI期刊审稿人以及国家自然科学基金评审专家。

代表成果

1. Yulong Liu, Liu Yang, Qing Bai, Wenbo Li, Yeqi Zhang, Ying Fu*, Fei Ye*, Highly efficient nondoped blue electroluminescence based on hybridized local and charge-transfer emitter bearing pyrene-imidazole and pyrene, Chemical Engineering Journal, 2021, 420, 129939, https://doi.org/10.1016/j.cej.2021.129939
2. Shuang Gao, Xiaoming Li, Jingyu Jiang, Lixia Zhao, Ying Fu*, Fei Ye*, Fabrication and characterization of thiophanate methyl/hydroxypropyl-β-cyclodextrin inclusion complex nanofibers by electrospinning, Journal of Molecular Liquids, 2021, 335, 116228, https://doi.org/10.1016/j.molliq.2021.116228
3. Ying Fu, Meng Wang, Li-Xia Zhao, Shuai-Qi Zhang, Yong-Xuan Liu, You-Yuan Guo, Dong Zhang, Shuang Gao, Fei Ye*. Design, synthesis, herbicidal activity and CoMFA of novel aryl-formyl piperidinone HPPD inhibitors, Pesticide Biochemistry and Physiology, 2021, 174, 104811, https://doi.org/10.1016/j.pestbp.2021.104811
4. Shuang Gao, Yanyan Liu, Jingyu Jiang, Xiaoming Li, Fei Ye*, Ying Fu*, Lixia Zhao, Thiram/hydroxypropyl-β-cyclodextrin inclusion complex electrospun nanofibers for a fast dissolving water-based drug delivery system, Colloids and Surfaces B: Biointerfaces, 2021, 201, 111625, https://doi.org/10.1016/j.colsurfb.2021.111625
5. Zi-Wei Wang, Li-Xia Zhao, Peng Ma, Tong Ye, Ying Fu*, Fei Ye*, Fragments recombination, design, synthesis, safener activity and CoMFA model of novel substituted dichloroacetylphenyl sulfonamide derivatives, Pest Management Science, 2021, 77, 1724-1738, DOI: 10.1002/ps.6193
6. Tao Kang, Shuang Gao, Li-Xia Zhao, Yue Zhai, Fei Ye*, Ying Fu*, Design, synthesis, and SAR of novel 1,3-disubstituted imidazolidine or hexahydropyrimidine derivatives as herbicide safeners, Journal of Agricultural and Food Chemistry, 2021, 69: 45-54, DOI: 10.1021/acs.jafc.0c04436J
7. Lu Li, Shuang Gao, Liu Yang, Yu-Long Liu, Ping Li, Fei Ye*, Ying Fu*, Cobalt (II) complex as a fluorescent sensing platform for the selective and sensitive detection of triketone HPPD inhibitors, Journal of Hazardous Materials, 2021, 404, 124015, DOI: https://doi.org/10.1016/j.jhazmat.2020.124015
8. Yuan-Yuan Zhang, Shuang Gao, Minh-Tu Hoang, Zi-Wei Wang, Xin Ma, Yue Zhai, Na Li, Li-Xia Zhao, Ying Fu*, Fei Ye*, Protective efficacy of phenoxyacetyl oxazolidine derivatives as safeners against nicosulfuron toxicity in maize, Pest Management Science, 2021, 77, 1, 177-183, DOI: 10.1002/ps.6005
9. Ke-Liang Guo, Li-Xia Zhao, Zi-Wei Wang, Ying-Chao Gao, Juan-Juan Li, Shuang Gao, Ying Fu*, Fei Ye*, Design, Synthesis, and Bioevaluation of Substituted Phenyl Isoxazole Analogues as Herbicide Safeners, Journal of Agricultural and Food Chemistry, 2020, 68(39): 10550-10559 DOI: https://dx.doi.org/10.1021/acs.jafc.0c01867
10. Liu Yang, Yu-Long Liu, Cheng-Guo Liu, Fei Ye, YingFu*, Two luminescent dye@MOFs systems as dual-emitting platforms for efficient pesticides detection, Journal of Hazardous Materials, 2020, 381: 120966, DOI: 10.1016/j.jhazmat.2019.120966

*以上信息由高级会员个人更新和维护。