祝诗发

男， 华南理工大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

1997.09-2001.07 湖南大学，本科生
2001.09-2006.07 中科院上海有机所，博士生
2006.09-2007.01 Syracuse University，博士后
2007.01-2009.01 University of South Florida ，博士后
2009.05-2013.08 华南理工大学，副教授
2013.09-现在 华南理工大学，教授

研究领域和兴趣

有机化学

主要业绩

主要从事碳-碳三键化学，已在Chem. Soc. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem等杂志发表SCI论文80余篇，授权PCT专利、美国专利、中国发明专利共二十余件。承担了包括教育部新世纪优秀人才计划、国家自然科学基金、973项目子课题、国家重点研发计划子课题、广东省自然科学基金等项目二十余项。
2009年5月进入华南理工大学化学与化工学院工作，2010年入选“教育部新世纪优秀人才支持计划”，2014年获“国家自然科学基金优秀青年基金”资助，同年入选“广东省千百十工程省级培养对象”，2015年入选“广东省特支计划百千万工程领军人才”，2016年入选“科技部中青年科技创新领军人才”，2017年入选国家“万人计划”领军人才。目前是广东省化学会理事，广州市化学化工学会理事，广东省化学会“有机化学专业委员会副主任”。

代表成果

[1] Chuntao Wang, Rui Wu, Kai Chen*, Shifa Zhu*, Enantioselective Synthesis of Biscyclopropanes Using Alkynes as Dicarbene Equivalents, Angew. Chem. Int. Ed. 2023, 62, e202305864.
[2] Shiwei Lü, Zipeng Wang, Xiang Gao, Kai Chen*, Shifa Zhu*, 1,2-Difunctionalization of Acetylene Enabled by Light, Angew. Chem. Int. Ed. 2023, 62, e202300268.
[3] Boxiang Liu, Zhicong Lin, Yu Wang, Tairan Cheng, Tongxiang Cao, Shifa Zhu*, Trimerization of Acetylene and Alkene: Rapid Access to Polyenes, CCS Chem., 2023, 5, 1077-1085.
[4] Shiwei Lü, Zipeng Wang and Shifa Zhu*, Thiol-Yne Click Chemistry of Acetylene-Enabled Macrocyclization, Nat. Commun.2022, 13, 5001.
[5] Bo Yang, Shaodong Lu, Yongdong Wang and Shifa Zhu*, Diverse Synthesis of C2-Linked Functionalized Molecules via Molecular Glue Strategy with Acetylene, Nat. Commun. 2022, 13, 1858.
[6] Rui Wu, Jiajun Lu, Tongxiang Cao, Jun Ma, Kai Chen*, Shifa Zhu*, Enantioselective Rh(II)-Catalyzed Desymmetric Cycloisomerization of Diynes: Constructing Furan-Fused Dihydropiperidines with an Alkyne-Substituted Aza-Quaternary Stereocenter, J. Am. Chem. Soc., 2021, 143, 14916-14925.
[7] Yang Chen, Pingchuan Shen, Tongxiang Cao, Hao Chen, Zujin Zhao* and Shifa Zhu*, Bottom-up Modular Synthesis of Well-Defined Oligo(arylfuran)s, Nat. Commun., 2021, 12, 6165.
[8] Bo Yang, Shi-Jun Li, Yongdong Wang*, Yu Lan*, Shifa Zhu*， Hydrogen radical-shuttle (HRS)-enabled photoredox synthesis of indanones via decarboxylative annulation. Nat. Commun., 2021, 5257.
[9] Dong Zhu, Lianfen Chen, Hanlin Fan, Qinglin Yao and Shifa Zhu*, Recent Progress on Donor and Donor-Donor Carbenes, Chem. Soc. Rev. 2020, 49, 908-950.
[10] Ling Zhang, Tongxiang Cao, Huanfeng, Jiang, and Shifa Zhu*, Deconstructive Reorganization: De Novo Synthesis of Hydroxylated Benzofuran Angew. Chem. Int. Ed. 2020, 59, 4670-4677.
[11] Lianfen Chen, Kai Chen, Shifa Zhu*, Transition Metal-Catalyzed Intramolecular Nucleophilic Addition of Carbonyl Group to Alkyne, Chem 2018, 4, 1208-1262.
[12] Dong Zhu, Lianfen Chen, He Zhang, Zhiqiang Ma, Huanfeng Jiang, and Shifa Zhu*, Catalyst-Controlled Highly Chemo- and Stereoselective Allylic C-H Insertion and Cyclopropanation of Donor/Donor-Carbenes, Angew. Chem. Int. Ed. 2018, 57, 12405-12409.
[13] Tongxiang Cao, Yi Kong, Kui Luo, Lianfen Chen, and Shifa Zhu*, Cascade Claisen Rearrangement: Rapid Synthesis of Polysubstituted Salicylaldehydes and Total Synthesis of Hemigossypol and Gossypol, Angew. Chem. Int. Ed. 2018, 57, 8702-8707.
[14] Dong Zhu, Jun Ma, Kui Luo, Hongguang Fu, Li Zhang*, Shifa Zhu*, Enantioselective Intramolecular C-H insertion of Donor- and Donor/Donor-Carbenes via a Non-Diazo Approach, Angew. Chem. Int. Ed., 2016, 55, 8452-8456.
[15] Renxiao Liang, Kai Chen, Qiaohui Zhang, Jiantao Zhang, Huanfeng Jiang, Shifa Zhu*, Rapid Access to 2-Methy lene Tetrahydrofurans and γ-Lactones: A Four-Step Tandem Process, Angew. Chem. Int. Ed., 2016, 55, 2587-2591.
[16] Shifa Zhu*, Qiaohui Zhang, Kai Chen, Huanfeng Jiang, Synergistic Catalysis: Metal/Proton-Catalyzed Cyclization of Alkynones Toward Bicyclo[3.n.1]alkanones, Angew. Chem. Int. Ed., 2015, 54, 9414-9418.
[17] Shifa Zhu*, Renxiao Liang, Huanfeng Jiang, Wanqing Wu, An Efficient Route to Polysubstituted Tetrahydronaphthols: Silver-Catalyzed [4+2] Cyclization of 2-Alkylbenzaldehydes and Alkenes, Angew. Chem. Int. Ed., 2012, 51, 10861-10865.
[18] Shifa Zhu, Tongxiang Cao, Yongdong Wang; Zhihuang Huang; Polysubstituted Benzene, Preparation Method Thereof, and Method of Using the Same, 2022, 美国专利号：16/986303；
[19] 祝诗发，曹同祥，王永东，黄志鹏，具有生物活性的多取代苯化合物及其制备方法和应用，2019, PCT专利号：WO2019153954A1；
[20] 江焕峰，祝诗发 译，[美]R.H.克拉布特里 著，过渡金属有机化学（原著第五版），科学出版社，2012年，北京；

*以上信息由高级会员个人更新和维护。