曾小明

男， 四川大学化学学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

1998.09—2002.07 四川师范大学，本科
2002.09—2004.07 广东省新兴华侨中学，高中教师
2004.09—2009.12 四川大学，博士研究生
2007.09—2009.09 加州大学河滨分校，联合培养博士研究生
2010.04—2011.12 东京大学，JSPS博士后
2012.01—2017.04 西安交通大学前沿科学技术研究院，教授
2017.05—至今 四川大学化学学院，教授

研究领域和兴趣

金属有机化学

主要业绩

带领研究团队以“开发新型铬金属有机催化体系”为目标，针对 “铬金属有机化学多局限于当量反应和高价金属催化研究”的现状及“活性的铬低价金属(<2+)催化剂和催化体系缺失”的内在原因，基于“金属因价态影响其外层d电子数及分布、导致催化性质迥异”的认知，瞄准“如何构促进铬低价金属催化”的研究策略，解决了“如何构建活性的铬低价金属催化剂”的领域研究难题，建立了多种铬低价金属有机催化反应新体系，实现了其它金属暂无法催化的一些惰性芳基碳-杂原子键交叉偶联的有机合成新反应、新方法，突破了当前铬金属有机催化多局限于当量反应及单电子转移催化的限制，揭示出铬低价金属以高自旋态参与双电子氧化加成自身特色的催化机制。
以第一或通讯作者身份在Nat. Synth., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Nat. Commun., Chem. Rev.等期刊发表SCI论文八十余篇, 包括十篇J. Am. Chem. Soc.，七篇Angew. Chem. Int. Ed.; 通讯作者论文单篇最高他引近500次。研究工作形成了国际上具有一定特色的体系，受Acc. Chem. Res.主编和Organometallics副主编邀请撰写铬低价金属有机催化综述及相关书籍章节；独立工作创制的催化剂已在日本被Tokyo Chemical Industry (TCI)试剂公司商品化，被Glorius和Bullock等国际著名研究团队应用，研究结果被Science, Nat. Chem., J. Am. Chem. Soc.等期刊正面评述和引用。曾获得德国Thieme化学期刊奖，日本和新加坡亚洲核心计划讲座奖; 担任Molecules、Chinese Chemical Letters、Current Chinese Chemistry Journal等杂志编委。

代表成果

1. 代表性论文：
(1) Zheng Luo,† Linhong Long,† Shuaiyong Zhao, Xiaoyu Zhang, Yong Peng, Meiming Luo, Hui Chen,* and Xiaoming Zeng*, Silylchromium-Catalyzed Selective Semihydrogenation of UndirectedAllenes by Sila-Metalation and β-Silyl Elimination. Angew. Chem. Int. Ed. 2025, 64, e202424273.
(2) Fei Fan,† Yong Peng,† Xiaoyu Zhang, Sha Wang, Zheng Luo, Meiming Luo, and Xiaoming Zeng*, Metal–carbene-guided twofold cross-coupling of ethers with chromium catalysis. Nat. Commun. 2024, 15, 6455.
(3) Fei Fan,† Linhong Long,† Liang Ling, Chao Li, Meiming Luo,* Hui Chen,* and Xiaoming Zeng*, Chemoselective chromium catalysed cross-coupling enables three-component tertiary alkane synthesis. Nat. Synth. 2023, 2, 1046–1058.
(4) Sha Wang,† Linhong Long,† Xiaoyu Zhang, Liang Ling, Hui Chen,* and Xiaoming Zeng*, Chemoselective Three-Component Geminal Cross Couplings of Dihaloalkanes with Cr Catalysis: Rapid Access to Tertiary and Quaternary Alkanes via a Metal–Carbene Intermediate. Angew. Chem. Int. Ed. 2023, 62(44) e202312856.
(5) Liang Ling, Chenyang Hu, Linhong Long, Xue Zhang, Lixing Zhao, Liu Leo Liu, Hui Chen*, Meiming Luo,* and Xiaoming Zeng*, Chromium-catalyzed stereodivergent E- and Z-selective alkyne hydrogenation controlled by cyclic (alkyl)(amino)carbene ligands. Nat. Commun. 2023, 14, 990.
(6) Xuefeng Cong, and Xiaoming Zeng*, Mechanistic Diversity of Low-Valent Chromium Catalysis: Cross-Coupling and Hydrofunctionalization. Acc. Chem. Res. 2021, 54 (8), 2014–2026.
(7) Lixing Zhao,§ Chenyang Hu,§ Xuefeng Cong, Gongda Deng, Liu Leo Liu, Meiming Luo, and Xiaoming Zeng*. Cyclic (Alkyl)(amino)carbene Ligand-Promoted Nitro Deoxygenative Hydroboration with Chromium Catalysis: Scope, Mechanism, and Applications. J. Am. Chem. Soc. 2021, 143(3), 1618−1629.
(8) Jinghua Tang,† Fei Fan,† Xuefeng Cong,† Lixing Zhao, Meiming Luo, and Xiaoming Zeng*, Reductive Cross-Coupling between Unactivated C(aryl)–N and C(aryl)–O Bonds by Chromium Catalysis Using a Bipyridyl Ligand. J. Am. Chem. Soc. 2020, 142(29), 12834-12840.
(9) Jinghua Tang,† Liu Leo Liu,† Shangru Yang,† Xuefeng Cong, Meiming Luo, and Xiaoming Zeng*, Chemoselective Cross-Coupling between Two Different and Unactivated C(aryl)–O Bonds Enabled by Chromium Catalysis. J. Am. Chem. Soc. 2020, 142 (17), 7715–7720.
(10) Bo Han, Pengchen Ma, Xuefeng Cong, Hui Chen,* and Xiaoming Zeng*, Chromium- and Cobalt-Catalyzed, Regiocontrolled Hydrogenation of Polycyclic Aromatic Hydrocarbons: A Combined Experimental and Theoretical Study. J. Am. Chem. Soc. 2019, 141 (22), 9018−9026.
2. 专利:
(1) 曾小明；韩波；罗美明；一种铬盐/甲基溴化镁选择性催化氢化多环芳烃的方法，中国，专利号：ZL 2017 1 0396279.3，授权日期2019-07-09，申请日期2017-05-31.
(2) 曾小明；韩波；罗美明；基于钴盐选择性催化氢化多环芳烃的方法，中国，专利号：ZL 2017 1 0396265.1，授权日期2019-07-09，申请日期2017-05-31.
(3) 曾小明；罗美明；张雪；凌亮；氢化合成顺式二氟甲基环已烷衍生物和杂环化合物的方法，中国，专利号：ZL 2019 1 0701039.9，授权日期2021-11-12，申请日期2019-07-31.
(4) 曾小明；罗美明；赵立兴；一种环状(烷基)(氨基)卡宾铬络合物催化还原硝基化合物制备胺的方法，中国，专利号：ZL 2020 1 1579010.7，授权日期2023-05-26，申请日期2020-12-28.
(5) 曾小明；罗美明；凡飞；一种合成1,1,2-三芳基乙烷的方法，中国，专利号：ZL 2023 1 0058556.5，授权日期2024-04-26，申请日期2023-01-18.
(6) 曾小明；罗美明；凡飞；一种合成二芳基硅基甲烷的方法，中国，专利号：ZL 2023 1 0056227.7，授权日期2024-05-28，申请日期2023-01-18.
(7) 曾小明；罗美明；凡飞；一种合成二芳基烷基甲烷的方法，中国，专利号：ZL 2023 1 0056611.7，授权日期2024-06-11，申请日期2023-01-18.
3. 著作：
(1) Xiaoming Zeng, Xuefeng Cong, Cr Complexes in Formal Oxidation States 1+ and 0 Values. In Comprehensive Coordination Chemistry III; Constable, E. C., Parkin, G., Que Jr, L., Eds., Vol. 4, Elsevier, 2021; pp 552–566.
(2) Xiaoming Zeng, Chromium-Catalyzed Cross Coupling and C–H Functionalization. In Science of Synthesis Base-Metal Catalysis; Yoshikai, N. Ed., Thieme Group, (2023) 2, 745–772.
(3) Yunqian Hou, Wen Xu, and Xiaoming Zeng, C–C Cross Couplings with Chromium Catalysis. In C-C Cross Couplings with 3d Base Metal Catalysts; X.-F. Wu, Ed. Top Organomet. Chem. (2023) 71: 1–16.

*以上信息由高级会员个人更新和维护。