李春霞

女， 中国海洋大学医药学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

1993/09-1997/06，青岛海洋大学，水产学院，本科学生
1997/09-2002/07，中国海洋大学，海洋药物与食品研究所，博士研究生
2002/07-2005/12，中国海洋大学，医药学院，讲师
2006/01-2013/12，中国海洋大学，医药学院，副教授
2008/09-2009/09，University of Georgia，访问学者
2014/01-至今，中国海洋大学，医药学院，教授

研究领域和兴趣

主要从事海洋糖类药物、医疗器械的研究与开发以及海洋先导化合物的结构优化

主要业绩

李春霞，博士，教授，博士生导师。现任中国海洋大学医药学院副院长，山东省糖科学与糖工程重点实验室副主任，教育部“新世纪优秀人才”计划资助获得者。2002年毕业于中国海洋大学获得博士学位，2002.07-至今在中国海洋大学医药学院工作，2008.09-2009.09年作为访问学者于美国佐治亚大学复杂碳水化合研究中心（University of Georgia，Complex Carbohydrate Research Center）进行糖化学与糖生物学方面的研究。目前主要从事海洋糖类药物、医疗器械的研究与开发以及海洋先导化合物的结构优化。近年来先后主持和参与国家自然科学基金、国家“863”计划、国家科技支撑计划、国家海洋局公益专项、国际合作交流项目及省市课题30余项。目前已发表文章80余篇，其中SCI收录论文40余篇，参与编写专著2部；获得授权国家发明专利15项；获得教学及科研奖励3项。

代表成果

(1) Shixin Wang, Zhe Lu, Shuyao Wang, Wei Liu, Jiangming Gao, Linan Tian, Li Wang, Xiaoshuang Zhang, Xia Zhao, Wei Wang*, Chunxia Li*, The inhibitory effects and mechanisms of polymannuroguluronate sulfate against human papillomavirus infection in vitro and in vivo, Carbohydr. polymers, 2020, 241, 116365
(2) He Ma#, Peiju Qiu#, Meng Xin, Ximing Xu, Zhuoya Wang, Huixin Xu, Rilei Yu, Xiaoxiao Xu, Chenyang Zhao, Xin Wang, Huashi Guan, Jinbo Yang*, Chunxia Li*, Structure-activity relationship of propylene glycol alginate sodium sulfate derivatives for blockade of selectins binding to tumor cells, Carbohydr. polymers,, 2019, 15, 225-233
(3) Yi-Ting Xue, Shuang Li, Wen-Jing Liu, Meng Xin, Hai-Hua Li, Guang-Li Yu, Hua-Shi Guan, Xiao-Xi He*, Chun-Xia Li*, The Mechanisms of Sulfated Polysaccharide Drug of Propylene Glycol Alginate Sodium Sulfate (PSS) on Bleeding Side Effect, Carbohydr. polymers, 2018, 195, 365-374
(4) Meng Xin, Yang Sun, Haijiao Chen, Quancai Li, Yunlou Dun, Huashi Guan, Jiejie Hao*, Chunxia Li*, Propylene glycol guluronate sulfate (PGGS) reduces lipid accumulation via AMP-activated kinase activation in palmitate-induced HepG2 cells, Int. J. Biol. Macromol., 2018, 114(15): 26-34
(5) Pengli Li, Jiejie Hao, Haihua Li, Huashi Guan, Chunxia Li*, Development of an enteric nanoparticle of marine sulfated polysaccharide PSS for oral administration: Formulation design, pharmacokinetics and efficacy, J Pharm and Pharmacol, 2018, 70, 740-748
(6) Quancai Li, Yangyang Zeng, Linlin Wang, Huashi Guan, Chunxia Li*, Lijuan Zhang*, The heparin-like activities of negatively charged derivatives of low-molecular-weight polymannuronate and polyguluronate, Carbohydr. polymers, 2017, 155, 313-320
(7) Yi-Ting Xue, Li Ren, Shuang Li, Lin-lin Wang, Xiao-Xi He, Xia Zhao, Guang-li Yu, Hua-Shi Guan, Chun-Xia Li*, Study on Quality Control of Sulfated Polysaccharide Drug, Propylene Glycol Alginate Sodium Sulfate (PSS), Carbohydr. polymers, 2016, 144, 330–337
(8) Meng Xin, Li Ren, Yang Sun, Hai-hua Li, Hua-Shi Guan, Xiao-Xi He*, Chun-Xia Li*, Anticoagulant and antithrombotic activities of low-molecular-weight propylene glycol alginate sodium sulfate (PSS), Eur. J. Med. Chem, 2016, 114, 33-40
(9) Li Ren#, Jun Zhang#, Haizhen Ma, Linlin Sun, Xiaoshuang Zhang, Guangli Yu, Huashi Guan, Wei Wang* and Chunxia Li*, Synthesis and Anti-Influenza A Virus Activity of 6ʹ-amino-6ʹ-deoxy-glucoglycerolipids Analogs, Mar. Drugs, 2016, 14(6), 116
(10) Jun Zhang, Chunxia Li*, Linlin Sun, Guangli Yu, Huashi Guan, Total synthesis of Myrmekioside A, a mono-O-alkyl diglycosylglycerol from marine sponge Myrmekioderma sp., Eur. J. Org. Chem., 2015, 19, 4246–4253
(11) Pengtao Zhang, Kun wang, Jun Zhang, Chunxia Li*, Huashi Guan, Total Synthesis of Sulfated Glycosphingolipid SM1a, A Kind of Human Epithelial Carcinoma Antigen, Eur. J. Org. Chem., 2015, 3, 570–583
(12) Cui Hao#, Lixia Gao#, Yiran Zhang, Wei Wang, Guangli Yu, Huashi Guan, Lijuan Zhang*, Chunxia Li*, Acetylated chitosan oligosaccharides act as antagonists against glutamate-induced PC12 cell death via Bcl-2/Bax signal pathway, Mar. Drugs, 2015, 13, 1267-1289

*以上信息由高级会员个人更新和维护。