李清寒

男， 西南民族大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

教育背景
(1). 2003.9 - 2006.6 四川大学化学学院 博士研究生 博士
(2). 2000.9 - 2003.6 四川大学化学学院 硕士研究生 硕士
(3). 1995.9 - 1998.6 四川师范大学化学学院 本科 学士
(4).1990.9 - 1993.6 西华大学理学院化学系化学教育专业学习
工作经历
(1). 2021.1 - 至今，西南民族大学化学与环境学院教授。
(2). 2019.4 - 2020.12，西南民族大学化学与环境学院副教授。
(2). 2019.1 - 2019.3，美国Missouri State University访问学者。
(3). 2011.8 - 2018.12，西南民族大学化学与环境学院副教授。
(4). 2009.8 - 2011.7，台湾中兴大学化学系博士后研究员。
(5). 2008.9 - 2009.7，西南民族大学化学与环境学院副教授。
(6). 2006.7 - 2008.8，西南民族大学化学与环境学院讲师。
(7). 1993.7 - 2000.6，广汉市第三高级中学校教师。

研究领域和兴趣

（1）金属催化的碳-碳/杂原子键形成的偶联反应。 (2). 绿色有机合成及生物有机化学。 (3). 不对称催化反应。

主要业绩

李清寒，男，博士，教授，西南民族大学化学与环境学院教师, 有机化学专业硕士生导师，，材料与化工专业硕士生导师，中国化学学会高级会员。毕业于四川大学化学学院教育部绿色化学与技术重点实验室有机化学专业，分别师从陈淑华教授和冯小明院士，于2003年和2006年分别获得理学硕士和理学博士学位。曾在台湾中兴大学从事博士后研究(2009-2011，合作导师：高汉谋教授)，美国Missouri State University (2019,1-3)访学。主讲本科生《有机化学》、《绿色化学》、《有机化学实验》以及研究生《金属有机化学》、《高等有机合成》等课程。出版《绿色化学》教材一部（主编）。指导学生参加各级各类化学竞赛获省级二等奖及三等奖多项。主要从事碳-氢活化反应、绿色有机合成及生物有机化学研究，在有机钛、铝试剂的合成及应用中取得了特色成果，包括发展有机钛、铝试剂应用于不对称合成、碳-碳/碳-杂原子的构建及具有生物活性的小分子化合物的合成等。主持/主研国家级项目1项，省级项目8项，其它项目14项。现已在Org. & Biom. Chem., Eur. J. Org. Chem., Tetrahedron, RSC Adv., J. Organomet. Chem.,等国内外核心期刊上发表学术论文100余篇，其中SCI收录90余篇，SCI总引用超过300次；申请国家发明专利3项，其中授权1项。目前担任科学技术部、四川省科技厅、成都市科技局、黑龙江科技厅、重庆市科技局、武汉市科技局、深圳市科技局及长沙市科技局科技项目评估专家；教育部学位中心研究生论文评审专家；国际重要英文期刊Chem. Commun., Org. Chem. Front., Org.Lett., RSC Adv., Appl. Organomet. Chem., Curr. Org. Chem., Curr. Org. Synth., Molecule, BMC Chem.,等杂志论文评审人。获西南民族大学教学质量二等奖，西南民族大学优秀教师，四川省海外高层次留学人才等荣誉。

代表成果

1. 文章
(1). Jiaxia Pu, Lironghan, Jinsong Hou, Hui Zhou,Xiaohao Shi, Qinghan Li*. Synthesis of Thioamides from the Cross-Coupling Reaction of Dithiocarbamates with Organotitanium and Organoalane Reagents. J. Org. Chem., 2026, 91, 8511- 8526.
(2). Hui Zhou, Xiaohao Shi, Xi Wei, Qinghan Li*. Recent advances in the synthesis of [1,2,3]triazolo[5,1-a]isoquinoline derivatives. Tetrahedron, 2026, 199, 135393.
(3). Xiaoying Jia, Hui Zhou, Xiaohao Shi, Jinsong Hou, Jiaxia Pu, Qinghan Li*. Copper Catalyzed the Cross-Coupling Reaction of Arylthioaluminum Reagents with Alkynyl Bromides/Terminal Alkynes. J. Org. Chem., 2025, 90, 16432- 16445.
(4). Jinsong Hou, Lirong Han, Qinghan Li*. Nickel-Catalyzed Coupling Reaction of Arylboronic Acid with Methyl Dithiocarbamates for the Synthesis of Thioamides. Lett. Org. Chem., 2025, 22(12), 973-980.
(5). Qinghan Li*, Lirong Han, Hui Zhou, Jinsong Hou, Xiaohao Shi. Advances in Synthetic Strategies for Indolo[2,1-a]isoquinoline Derivative. Adv. Synth & Catal., 2025, 367, e202500035. DOI:10.1002/adsc.202500035.
(6). Lirong Han, Hui Zhou, Jinsong Hou, Xiaohao Shi and Qinghan Li*. The formation reaction of a carbon-carbon bond promoted by Eosin-Y under visible light. Org. Biomol. Chem., 2025, 23, 3741- 3799. DOI: 10.1039/D5OB00141B.
(7). Qinghan Li*, Yaning Han, Jiaxia Pu, Xiaoying Jia, Lirong Han, Jinsong Hou, Liuxian Wei and Wanchao Ma. Research Progress on the Formation of C-C Bonds through Photoinduced Cross-coupling Reactions Involving Katritzky Salts. Mini-Rev. Org. Chem., 2025, 22(6), 17. DOI: 10.2174/011875629830753724072 2112735.
(8). Jia-Xia Pu, Jin-Song Hou, Li-Rong Han, Xiao-Ying Jia, Qing-Han Li*. Synthesis of the 2-alkynyl benzo[b]furanes/benzo[b]thiophenes from the cross-coupling reaction of benzo[b]furanyl/benzo[b]thiophene aluminum reagents with gem- dibromooleffn derivatives catalyzed by palladium. Tetrahedron, 2024, 162, 134089. DOI: 10.1016/j.tet.2024.134089.
(9). Zhi-Hao Zhang, Jia-Xia Pu, Xiao-Ying Jia, Jin-Song Hou, Li-Rong Han, Chuan Wu, Qing-Han Li*. Highly efffcient synthesis of arylsulffde derivatives from coupling reaction of aryl titanium reagents with N-aryl thiosuccinimides catalyzed by copper under ligand-free conditions. J. Organomet. Chem., 2024, 1014,123192. DOI: 10.1016/j.jorganchem.2024.123192.
(10). Zhihao Zhang, Xiaoying Jia, Jiaxia Pu, Lirong Han, Jinsong Hou and Qinghan Li*. Ligand-Free, Copper-Catalyzed Coupling Reaction of Aryl Aluminum Reagents with N-Aryl Thiosuccinimides. Lett. Org. Chem., 2024, 21, 1055-1063. DOI: 10.2174/0115701786298931240408083720.
(11). Shaopeng Guo, Yujun Li, Qinghan Li* and Ke Zheng*. Electrochemical desulfurative formation of C–N bonds through selective activation of inert C(sp3)–S bonds. ChemComm, 2024, 60, 2501-2504. DOI: 10.1039/d4cc00142g
(12). Hong-Liu Xiao, Xiao-Ying Jia, Jia-Xia Pu, Li-Rong Han, Qing-Han Li*. Copper-assisted palladium catalyzed the cross-coupling reaction of Alknylalane reagents with 2-Thiobenzo[d]thiazoles via C–S bond cleavage. Tetrahedron, 2024, 153,133850. DOI: 10.1016/j.tet.2024.133850.
(13). Yujun Li, Shaopeng Guo, Qing-Han Li & Ke Zheng*. Metal-free photo induced C(sp3)–H/C(sp3)–H cross-coupling to access α‑tertiary amino acid derivatives. NatCommun., 2023, 14:6225. DOI:10.1038/s41467-023-41956-6.
(14). Meng Liang, Jiaxia Pu, Xiaoying Jia, Lirong Han, Qinghan Li*. Palladium- catalyzed Cross-coupling of 2-Benzo[b]thiophene or 2- Benzo[b]furan Aluminum with Heteroaryl or Alkynyl Bromides for the Synthesis of 2-Hetroaryl or Alkynyl Benzo[b]thiophene or Benzo[b]furan Derivatives. Lett. Org. Chem., 2024, 21(2):116-123. DOI: 10.2174/1570178620666230821142 342.
(15). Xiaoying Jia, Jiaxia Pu, Lirong Han, Qinghan Li*. Research progress in the synthesis of benzo[d]pentamembered heterocyclic thioethers containing two heteroatoms. Chin. J. Org. Chem., 2024, 44(1): 18-40. DOI: 10.6023/cjoc2023 06003.
(16). Jiaxia Pu, Xiaoying Jia, Lirong Han, Qinghan Li*. Research Progress of Visible Light Promoted C-C Bond Fracture to Construct C-C Bond. Chin. J. Org. Chem.,2023, 43(8): 2591-2613. DOI: 10.6023/cjoc202302002.
(17). Jiang Xin, Xiao Hongliu, Jia Xiaoying, Pu Jiaxia, Han Lirong, Li Qinghan*. The cross-coupling reaction of organoalane reagents with 2-methyl thiobenzo[d] thiazoles via C-S bond cleavage catalyzed by nickel. New J. Chem., 2023, 47, 14078-14094. DOI: 10.1039/d3nj02026f.
(18). Qing-Han Li*, Hong-Liu Xiao, Xiao-Ying Jia, Jia-Xia Pu, Li-Rong Han, and Chuan Wu. Recent advances in cross-coupling reactions of trialkoxy titanium reagents (RTi(OR’)3) with electrophilic reagents. Tetrahedron, 2023, 139, 133451. DOI: 10.1016/j.tet.2023.133451.
(19). Hongliu Xiao, Gang Zhang, Ruiqiang Luo, Qinghan Li*. Simple and efficient nickel-catalyzed cross-coupling reaction of alkenylalanes with alkynyl halides for synthesis of conjugated enynes. Tetrahedron, 2022, 103, 132549. DOI:10.10 16/ j.tet. 2021.132549.
(20). Ruiqiang Luo, Shaopeng Guo, Hongliu Xiao and Qinghan Li*. Cross- coupling reaction of organoalane reagents with 2-mercaptobenzo- 5-membered heterocycles for efficient synthesis of benzo-5-membered heterocycle sulfides. Tetrahedron, 2022, 103, 132564. DOI:10.1016/j.tet.2021.132564.
(21). Li Qinghan*, Jiang Xin, Wu Kun, Luo Ruiqiang, Zhang Zhihao, Liang Meng and Huang Zheyao. Recent Advances in the Cross-Coupling of Arylaluminums with Electro-phile Reagents. Mini-Rev. Org. Chem. 2021,18 (2): 213-220. DOI: 10.21 74/1570193X17999200723160453.
(22). Chuan Wu, Qinghan Li*. Highly efficient synthesis of 1,2-disubstituted acetylenes derivatives from the cross-coupling reactions of 1-bromoalkynes with organotitanium reagents. Tetrahedron, 2021, 74, 6063-6070. DOI: 10.1016/j.tet. 2021.132370.
(23). Chang Wen, Chuan Wu, Ruiqiang Luo, Qinghan Li*, Feng Chen. Highly Efficient Synthesis of 2-Substituted Benzo[b]furan Derivatives from the Cross-Coupling Reactions of 2-Halobenzo[b]furans with Organoalane Reagents. Synthesis 2021, 53(20), 3847-3861. DOI: 10.1055/a-1516-8745.
(24).Chang Wen, Xin Jiang, Kun Wu, Ruiqiang Luo, Qinghan Li*. Palladium- catalyzed cross-coupling reaction of alkenyl aluminums with 2-bromobenzo[b] furans. RSC Advance. 2020, 10, 19610 - 19614. DOI: 10.1039/d0ra02984j.
(25).Qinghan Li*, Xin Jiang, Kun Wu, Ruiqiang Luo, Meng Liang, Zhihao Zhang, Zheyao Huang. Research Progress on the Catalytic Enantioselective Synthesis of Axially Chiral Allenes by Chiral Organocatalysts. Curr. Org. Chem., 2020, 24, 694-708. DOI: 10.2174/1385272824666200 306094427.
(26).Gang Zhang, Kun Wu, Chang Wen, Qinghan Li*. Nickel-catalyzed cross- coupling of organoaluminum reagents with alkynylhalides for the synthesis of symmetrical and unsymmetrical conjugated 1,3-diynes derivatives. J. Organomet.Chem.,2020,906,121040.DOI: 10.1016/j.jorganchem. 2019. 1210 40.
(27).Qinghan Li*, Jinshuai Wang, Chang Wen, Xin Jiang, Kangping Cao, Kun Wu, Meng Liang. Research progress on cross-coupling reactions of alkynylaluminum with electrophiles reagents. Chin. Chem. Lett., 2019, DOI:10. 1016/j.cclet. 2019. 02.028.
(28).Xuebei Shao, Xin Jiang, Qinghan Li*, Zhigang Zhao. Highly efficient synthesis of 1,2-disubstituted acetylenes derivatives from the cross-coupling reactions of 1-bromoalkynes with organoalane reagents. Tetrahedron 2018, 74, 6063-6070. DOI: 10.1016/ j.tet. 2018. 08.050.
(29). Xuebei Shao, Zhen Zhang, Qinghan Li*, Zhigang Zhao. Synthesis of multi-substituted allenes from organoalane reagents and propargyl esters by using a nickel catalyst. Org. Biomol. Chem., 2018, 16, 4797- 4806. DOI: 10.1039/c8ob00781k.
(30).Zhen Zhang, Xuebei Shao, Gang Zhang, Qinghan Li*, Xinying Li. Highly Efficient Synthesis of Multi-Substituted Allenes from Propargyl Acetates and Organoaluminum Reagents Mediated by Palladium. Synthesis, 2017, 49, 3643- 3653. DOI: 10.1055/s-0036-1588177.
(31). Zhen Zhang, Song Mo, Gang Zhang, Xuebei Shao, Qinghan Li*, Ying Zhong. Synthesis of Multisubstituted Allenes via Palladium-Catalyzed Cross-Coupling Reaction of Propargyl Acetates with an Organo-aluminum Reagent. Synlett, 2017, 28,611-614.DOI: 10.1055/s-0036-1588389.
2.教材.
李清寒，赵志刚。教材《绿色化学》(2017年，化学工业出版社，主编)。
3.专利
(1). 李清寒，姜芯。Synthetic Method of 2-Substituted Benzo[d]thiazole Derivatives. REPUBLIC OF SOUTH AFRICA PATENTS ACT, 2022-09326.
(2).李清寒，曹康平。一组索马鲁肽类似物及其制备方法和应用。(CN202210872536.7)
(3). 曹冶, 李键, 靳亚平, 李清寒, 张红, 赵素君, 李红, 周洪群. 一种法氏囊素三肽合成方法。(CN2005100209107，公开号：1696151, 2005,11,16).

*以上信息由高级会员个人更新和维护。