吴春惠

女， 电子科技大学， 副教授/副研究员/高级工程师或同等级别

学习/工作经历

2001.09-2005.06 南京师范大学 化学与环境科学学院 学士
2005.09-2010.10 东南大学 生物医学工程学院　　 博士
2010.10-2013.08 电子科技大学 生命科学与技术学院 讲师
2013.08-2014.08 美国MD安德森癌症中心 癌症系统成像系 访问学者
2013.08-至 今 电子科技大学 生命科学与技术学院 副教授
2018.12-至 今 电子科技大学 生命科学与技术学院 博导

研究领域和兴趣

纳米生物医学

主要业绩

本人十余来始终聚焦恶性肿瘤微环境制约疗效的挑战性问题，在外源性物理刺激和内源性生物因素协同响应和时空调控的纳米医学诊疗体系和仿生药物方面开展了深入研究，研究成果为恶性肿瘤的高效诊治提供了新策略、新途径。先后主持了国家自然科学基金项目3项，四川省科技厅项目2项，中国博士后科学基金特别资助和面上项目2项。作为核心研究人员，参与国家自然科学基金重点项目2项，省科技厅重点项目和青年基金2项。迄今在生物医学领域和生物材料领域国际期刊ACS Nano、Biomaterials、Acta Biomaterialia、Advanced Healthcare Materials、ACS Applied Materials & Interfaces、Theranostics等上发表SCI收录论文八十余篇，其中第一作者/共同第一作者/通讯作者SCI 论文23篇、IF＞10的论文9篇，JCR一区论文20篇，SCI他引2800余次，SCI H-Index 34，授权国家发明专利6项。多次参加国际/国内相关学术会议，报告相关研究成果，获得纳米生物医学、生物材料研究领域国内外和省内外专家的高度认可和评价，获2019年第四届中美纳米医学与纳米生物技术年会(CASNN)”未来之星”奖（TOP 12）。

代表成果

[1]. Xiaodan Wei, Ningxi Li, Honglin Huang, Geng Yang, Hanxi Zhang, Tingting Li, Xiang Qin, Shun Li, Lulu Cai, Hong Yang, Chunhui Wu (*), Yiyao Liu (*), Homologous Targeting Cascade Nanobioreactor for Autophagy Inhibition Amplified Tumor Catalytic Therapy, ACS Materials Lett. 2023, 5, 491−503.
[2]. Chunhui Wu(*), Yingxue Zhang, Xiaodan Wei, Ningxi Li, Honglin Huang, Zhengxin Xie, Hanxi Zhang, Geng Yang, Mengyue Li, Tingting Li, Hong Yang, Shun Li, Xiang Qin, Yiyao Liu(*), Tumor homing-penetrating and nanoenzyme-augmented 2D phototheranostics against hypoxic solid tumors, Acta Biomaterialia, 2022, 150, 391-401.
[3]. Chunhui Wu(*), Qiuyue Liu, Yikun Wang, Zhengxin Xie, Honglin Huang, Ningxi Li, Xiaodan Wei，Geng Yang，Tingting Li, Hong Yang, Shun Li, Xiang Qin, Yiyao Liu(*), Tirapazamine encapsulated hyaluronic acid nanomicelles realized targeted and efficient photo-bioreductive cascading cancer therapy, Chinese Chemical Letters, 2021, 32, 2400-2404.
[4]. Xiaodan Wei, Ningxi Li, Yikun Wang, Zhengxin Xie, Honglin Huang, Geng Yang, Tingting Li, Xiang Qin, Shun Li, Hong Yang, Jie Zhu, Fengming You, Chunhui Wu(*), Yiyao Liu(*), Zeolitic imidazolate frameworks-based nanomaterials for biosensing, cancer imaging and phototheranostics, Applied Materials Today, 2021, 23, 100995.
[5]. Chunhui Wu (*)(#), Jiming Xu (#), Zhengxin Xie , Honglin Huang, Ningxi Li , Xiaodan Wei, Tingting Li , Hong Yang, Shun Li, Xiang Qin, Yiyao Liu (*), Light-responsive hyaluronic acid nanomicelles co-loaded with an IDO inhibitor focus targeted photoimmunotherapy against “immune cold” cancer, Biomaterials Science, 2021, 9 (23), 8019-8031.
[6]. Chunhui Wu(*), Yuan Tian, Yingxue Zhang, Jiming Xu, Yikun Wang, Xiaotian Guan, Tingting Li, Hong Yang, Shun Li, Xiang Qin, Yiyao Liu(*), Acid-triggered charge-convertible graphene-based all-in-one nanocomplex for enhanced genetic phototherapy of triple-negative breast cancer, Advanced Healthcare Materials, 2020, 9, 1901187.
[7]. Chunhui Wu, Xiaotian Guan, Jinming Xu, Yingxue Zhang, Qiuyue Liu, Yuan Tian, Shun Li, Xiang Qin, Hong Yang, Yiyao Liu(*), Highly Efficient cascading synergy of cancer photo-immunotherapy enabled by engineered graphene quantum dots/photosensitizer/CpG oligonucleotides hybrid nanotheranostics. Biomaterials, 2019, 205, 106-119.
[8]. Chunhui Wu, Lianhui Wang, Yuan Tian, Xiaotian Guan, Qiuyue Liu, Shun Li, Xiang Qin, Hong Yang, Yiyao Liu(*), "Triple-punch" anticancer strategy mediated by near-infrared photosensitizer/CpG oligonucleotides dual-dressed and mitochondria-targeted nanographene, ACS Applied Materials & Interfaces, 2018, 10(8), 6942-6955.
[9]. Chunhui Wu, Dan Li, Lianhui Wang, Xiaotian Guan, Yuan Tian, Hong Yang, Shun Li, Yiyao Liu(*), Single wavelength light-mediated, synergistic bimodal cancer photoablation and amplified photothermal performance by graphene/gold nanostar/photosensitizer theranostics, Acta Biomaterialia, 2017, 53, 631-642.
[10]. Chunhui Wu, Qiuming He, Anni Zhu, Dan Li, Min Xu, Hong Yang, Yiyao Liu(*), Synergistic anticancer activity of photo- and chemoresponsive nanoformulation based on polylysine-functionalized graphene, ACS Applied Materials & Interfaces, 2014, 6, 21615-21623.

*以上信息由高级会员个人更新和维护。