陈学元

男， 中国科学院福建物质结构研究所， 教授/研究员/教授级高工或同等级别

学习/工作经历

1988.9-1993.7 中国科学技术大学材料科学与工程系 材料化学 理学学士
1993.9-1998.6 中国科学院福建物质结构研究所 物理化学 理学博士
1998.7-2001.8 中国科学院福建物质结构研究所 助研、副研究员
2001.8-2005.1 美国能源部阿贡国家实验室化学部 博士后/研究助理
2005.1-2016.8 中国科学院福建物质结构研究所 课题组长/研究员
2016.8-2025.3 中国科学院福建物质结构研究所 材料工程中心副主任、主任，中科院功能纳米结构设计与组装重点实验室主任，福建省纳米材料重点实验室主任
2025.3-至今 中国科学院福建物质结构研究所 结构化学全国重点实验室组群主任，福建省纳米材料重点实验室主任

研究领域和兴趣

无机发光材料、稀土光功能材料

主要业绩

陈学元，国家杰青获得者，入选科技部中青年科技创新领军人才，国家"万人计划"科技创新领军人才和国家百千万人才工程，担任发光学领域国际知名期刊Journal of Luminescence主编。致力于发光纳米生物标记材料研究，在无机发光材料电子结构、光学性能及应用取得重要进展，例如，在国际上率先研制基于稀土氟化物和氧化物纳米探针的新一代荧光生物标记材料，并成功用于生物分子尤其是肿瘤标志物的异相和均相检测。近三年已在美国化学会志、德国应用化学、自然-通讯等发表SCI论文66篇，其中影响因子>11的22篇，3篇入选ESI化学和材料领域高被引论文，论文近三年他引5300次（H指数 57）。入选爱思唯尔化学领域中国高被引学者榜单（2018，2019），英国皇家化学会综合化学领域Top 1%高被引中国作者榜单（2017）和《德国应用化学》Author Profile人物专栏。申请国内外发明专利35项（授权14项）。系列研究成果入选 "中国稀土十大科技新闻"（2018，2019），获中科院上海分院首届"身边优秀榜样"先进工作者（2019），2018年度中国稀土科学技术奖一等奖（基础研究类，第一完成人），2017年度福建省自然科学奖二等奖。根据科睿唯安文献检索报告，近十年（2010年至今），按"第一作者+通讯作者"发文数排序，陈学元团队在"发光纳米生物标记材料及应用"研究领域的SCI论文数量排名国际第一。

陈学元致力于发光材料电子结构与性能研究，设计研制低温高分辨激光光谱仪和上转换量子产率测试仪，自主研制了综合指标国际领先的光化学与光物理测试研究平台，发现许多新颖的光学性能；依托该平台目前已建成国际知名的固体光谱学与光物理国际研究中心，与众多国内外伙伴小组合作，取得许多高水平成果。近三年在无机发光材料尤其是稀土荧光标记的控制合成、电子结构、光学性能及生物应用等方面取得系列重要成果：

1、发光材料的电子结构和激发态动力学
以Eu3+为结构探针，利用变温高分辨光谱等手段，精确指认出LiLuF4:Nd3+纳米晶36条源自Nd3+的4F3/2 → 4IJ晶体场跃迁的发射谱线和20个Stark子能级位置（Adv Sci 2019）。通过电子束辐照同质包覆，证实稀土掺杂NaLuF4纳米颗粒内核与壳层界面处存在大量晶体缺陷；利用界面缺陷调控，首次在碳膜衬底上原位构筑中空核壳结构稀土上转换纳米晶（Adv Sci 2018,入选2018年度中国稀土十大科技新闻）。

2、发光材料的光学性能设计
首创替位锰稳定钙钛矿晶格的"内部攻坚"策略，从钙钛矿内部晶格的原子尺度不稳定性机制入手，指出该体系中形成能过低引起的晶格失稳，进而设计了Mn2+替位掺杂提升形成能与稳定性的策略，解决全无机钙钛矿量子点热稳定性差的难题，并大幅提高了其激子发光效率（JACS 2017）。

提出一种辐射能量传递上转换新机制，利用稀土纳米晶到全无机钙钛矿量子点的辐射能量传递，实现CsPbX3量子点在低功率半导体激光器激发下的高效上转换发光，并通过剪裁量子点带隙和稀土荧光寿命，实现可见波段全光谱上转换发光和超长激子荧光寿命的调控（Nat Commun 2018）。发展了一种基于CsPbX3钙钛矿量子点长余辉光转换新策略，以发蓝紫光的稀土长余辉粉作为光存储材料，实现可见波段全光谱的高效长余辉发光，突破了传统长余辉材料红光组分不足、余辉衰减不一致、发射谱带宽的应用瓶颈（Angew Chem 2019）。

利用简单的反向离子交换反应制备K2TiF6:Mn4+@K2TiF6核壳结构红色荧光粉，同时显著提高其抗湿性能和发光效率，器件双85老化480小时流明效率保持高达89%，制备的暖白光LED色温/显色指数/流明效率等综合指标为同类器件国际最高水平（Angew Chem 2019，热点论文）。

3、发光材料的生物医学应用
在国际上率先研制基于稀土氟化物和氧化物纳米探针的新一代荧光生物标记材料，并成功用于生物分子尤其是肿瘤标志物的异相和均相检测。建立基于稀土纳米晶溶解增强的荧光免疫分析方法（DELBA），该方法比目前最灵敏的商用镧系解离增强荧光免疫分析（DELFIA）试剂盒灵敏度提高近3个数量级，基于DELBA新型试剂盒已实现对人血清肿瘤标志物CEA、PSA和AFP的高灵敏特异性检测（获中美日等国专利授权，入选年度中国稀土十大科技新闻）。发展了基于稀土纳米探针标记的循环肿瘤细胞检测方法，利用纳米粒子溶解增强发光特性实现信号放大，同时借助Eu离子长寿命荧光去除短寿命荧光背景的干扰，实现全血中循环肿瘤细胞的免富集直接检测，其检测限低至1 CTC/well，对不同临床分期的乳腺癌患者进行血液CTC检测，可实现93.9%阳性检出率（Angew Chem 2019，入选2019年度中国稀土十大科技新闻），《德国应用化学》新闻专栏、Wiley主网和 ChemistryViews进行了专门亮点评述。

提出近红外双激发比率型上转换策略实现细胞内生物分子的精准检测，利用近红外染料IR808到Yb/Er共掺NaGdF4上转换纳米颗粒的高效能量传递和低背景荧光信号，实现对活细胞MCF-7中内源性和外源性ClO-的精确定量分析（Adv Sci 2019）。

研制出单分散、形貌粒径可控兼具高效近红外二区发光的稀土掺杂CaS纳米晶，蓝光LED激发下实现对肿瘤标志物黄嘌呤的高灵敏特异性体外检测，检测限达32 nM（Angew Chem 2019）。发展了一种氧化石墨烯修饰稀土纳米探针的探针功能化策略，获得单分散、高效上转换/下转移发光的氧化石墨烯包覆稀土纳米晶二元纳米结构，实现肿瘤细胞内纳米探针实时定位追踪和microRNA可视化成像，以及小鼠肿瘤靶向的无背景高灵敏近红外二区发光成像（Angew Chem 2019）。

代表成果

1. Zhiqing Shao, Wei Zhang*, Chenyin Zheng, Ping Huang*, Junxiang Liu, Xiaodong Yi, Xiaorong Song*, Zhuo Chen, Wei Zheng*, and Xueyuan Chen*, “NIR-I-rechargeable multi-wavelength NIR-II persistent luminescence in lanthanide-doped CaSnO3 via Bi2+ sensitization”, Mater. Today 2026, 98, 103421. DOI: 10.1016/j.mattod.2026.103421.
2. Qianqi Yang#, Chenliang Li#, Datao Tu*, Xiaoying Shang*, Wei Lian, Jiang Han, Fei Wen, Shiqi Yu, Zewei Quan*, and Xueyuan Chen*, “Ultrasensitive Pressure-Responsive Upconversion Luminescence in Cs2NaBiCl6:Yb3+/Mn2+ Optical Manometry”, Adv. Mater. 2026, 38, e73505. DOI: 10.1002/adma.73505.
3. Zhuo Li#, Xingyang Liu#, Shan Lu*, Xingjun Li*, Tao Dai, Yan Liu, Lijuan Liu, Hang Gao, Wenwu You, Jianxi Ke, Shanyong Zhou, Datao Tu, Zhuo Chen, and Xueyuan Chen*, “Boosting single-particle luminescence of nanoprobes via in-situ enrichment of lanthanide fluorides in dendritic silica for ultrasensitive cancer detection”, Sci. Bull. 2026, 71, 2696-2700. DOI: 10.1016/j.scib.2026.04.060.
4. Fei Wen#, Huihong Li#, Datao Tu*, Wei Lian*, Shiqi Yu, Meiqi Zhang, Qingyan Liu, Ping’an Ma, and Xueyuan Chen*, “Lanthanide-Doped Photo-Stimulated Luminescence Materials: From Trap Manipulation to Applications”, Adv. Funct. Mater. 2026, 36, e29409. DOI: 10.1002/adfm.202529409.
5. Chenliang Li, Luping Wang*, Datao Tu*, Xiaoying Shang, Mingjie Yang, Jiacheng Gong, Fei Wen, Yun Xing, Zhi Xie, Jiaxin Jiang, Shaohua Yu, and Xueyuan Chen*, “Luminescence Lifetime Thermometers Based on Hybrid Cuprous Halides with Exceptional Water Resistance and Giant Thermal Expansion”, Light Sci. Appl. 2025, 14, 224. DOI: 10.1038/s41377-025-01910-1 (“Hybrid cuprous halides enable high-sensitivity luminescence lifetime thermometry with exceptional water resistance”, highlighted in Light Sci. Appl. 2025, 14, 364. DOI: 10.1038/s41377-025-02041-3).
6. Wei Zhang, Wei Zheng*, Lingyun Li*, Xiaoying Shang*, Ping Huang, Xiaodong Yi, Hao Zhang, Yan Yu, and Xueyuan Chen*, “Multiphoton-Excited Upconversion Luminescence and Amplified Spontaneous Emission from Te4+-Doped Cs2SnCl6 Nanocrystals”, ACS Nano 2025, 19, 18866-18873. DOI: 10.1021/acsnano.5c05992.
7. Shuo Zhang#, Xiaoke Hu#, Ping Huang*, Xiaoying Shang, Dengfeng Yang, Zhiqing Shao, Xiaoyue Wang, Wei Zheng*, and Xueyuan Chen*, “Unraveling the Excited-State Dynamics of Er3+ in LiErF4-Based Upconversion Nanoparticles”, Nano Lett. 2025, 25, 7426-7434. DOI: 10.1021/acs.nanolett.5c00884.
8. Wen Zhang, Wei Zheng*, Ping Huang*, Dengfeng Yang, Zhiqing Shao, Wei Zhang, Hao Zhang, Zhi Xie, Jin Xu, and Xueyuan Chen*, “Intense upconverted ultraviolet emission of Er3+ through confined energy transfer in Yb3+/Er3+ co-doped Rb3InCl6”, Nat. Commun. 2025, 16, 6762. DOI: 10.1038/s41467-025-58901-4 (featured as Editors’ Highlights in Inorganic and Physical Chemistry on August 21, 2025).
9. Yuhan Liu, Datao Tu*, Mingjie Yang, Huihong Li, Chenliang Li, Zhi Xie*, Shanshan Zhou, Shaohua Yu, Jin Xu, and Xueyuan Chen*, “Near-Infrared and Visible Dual-Band Self-Trapped Exciton Emissions from Li+-Doped Cs2NaScCl6 Double Perovskites”, ACS Energy Lett. 2025, 10, 2150-2159. DOI: 10.1021/acsenergylett.5c00182 (入选2025年度中国稀土十大科技新闻).
10. Mengwei Zhou, Ping Huang*, Xiaoying Shang*, Ruihuan Zhang, Wen Zhang, Zhiqing Shao, Shuo Zhang, Wei Zheng*, and Xueyuan Chen*, “Ultrafast upconversion superfluorescence with a sub-2.5 ns lifetime at room temperature”, Nat. Commun. 2024, 15, 9880. DOI: 10.1038/s41467-024-54314-x (入选2024年度中国稀土十大科技新闻).
11. Hang Gao, Yan Liu*, Wei Lian, Ping Hu, Xiaoying Shang, Mingmao Chen, Xiaorong Song, Tianyong Guan, and Xueyuan Chen*, “Near-Infrared Circularly Polarized Light Triggered Phototherapy Based on Hybrid CuInSe2 Quantum Dot Hydrogels”, Nano Today 2024, 58, 102436. DOI: 10.1016/j.nantod.2024.102436.
12. Wei Zhang, Wei Zheng*, Lingyun Li*, Ping Huang, Jin Xu, Wen Zhang, Zhiqing Shao, and Xueyuan Chen*, “Unlocking the Potential of Organic-Inorganic Hybrid Manganese Halides for Advanced Optoelectronic Applications”, Adv. Mater. 2024, 36, 2408777. DOI: 10.1002/adma.202408777 (ESI高被引论文).
13. Zhuo Li, Shan Lu*, Wenzhen Liu, Zhuo Chen, Yunmei Huang, Xingjun Li, Jiacheng Gong, and Xueyuan Chen*, “Customized Lanthanide Nanobiohybrids for Noninvasive Precise Phototheranostics of Pulmonary Biofilm Infection”, ACS Nano 2024, 18, 11837-11848. DOI: 10.1021/acsnano.4c00777.
14. Wei Lian, Datao Tu*, Xukeng Weng, Kaiyu Yang*, Decai Huang, Haomiao Zhu*, Fushan Li, Zhi Xie, and Xueyuan Chen*, “Near-Infrared Nanophosphors Based on CuInSe2 Quantum Dots with Near-Unity Photoluminescence Quantum Yield for Micro-LEDs Applications”, Adv. Mater. 2024, 36, 2311011. DOI: 10.1002/adma.202311011.
15. Luping Wang, Datao Tu*, Chenliang Li, Siyuan Han, Fei Wen, Shiqi Yu, Xiaodong Yi, Zhi Xie*, and Xueyuan Chen*, “Engineering Trap Distribution to Achieve Multicolor Persistent and Photostimulated Luminescence from Ultraviolet to Near-Infrared-II”, Matter 2023, 6, 4261-4273. DOI: 10.1016/j.matt.2023.09.016 (Highlighted in Previews: “Designing multifunctional electron-trapping materials with tunable afterglow”, Matter 2024, 7, 297-299, February 7, 2024).
16. Wei Zhang, Ping Sui, Wei Zheng*, Lingyun Li*, Shuaihua Wang, Ping Huang, Wen Zhang, Qi Zhang, Yan Yu, and Xueyuan Chen*, “Pseudo-2D Layered Organic-Inorganic Manganese Bromide with a Near-Unity Photoluminescence Quantum Yield for White Light-Emitting Diode and X-Ray Scintillator”, Angew. Chem. Int. Ed. 2023, 62, e202309230. DOI: 10.1002/anie.202309230 (化学领域ESI高被引论文).
17. Siyuan Han, Datao Tu*, Zhi Xie, Yunqin Zhang, Jiayao Li, Yifan Pei, Jin Xu, Zhongliang Gong, and Xueyuan Chen*, “Unveiling local electronic structure of lanthanide-doped Cs2NaInCl6 double perovskites for realizing efficient near-infrared luminescence”, Adv. Sci. 2022, 9, 2203735. DOI: 10.1002/advs.202203735 (ESI高被引论文).
18. Yifan Pei, Datao Tu*, Chenliang Li, Siyuan Han, Zhi Xie, Fei Wen, Luping Wang, and Xueyuan Chen*, “Boosting Near-Infrared Luminescence of Lanthanide in Cs2AgBiCl6 Double Perovskites via Breakdown of the Local Site Symmetry”, Angew. Chem. Int. Ed. 2022, 61, e202205276. DOI: 10.1002/anie.202205276 (featured as Hot Paper, 化学领域ESI高被引论文).
19. Jinyue Sun, Wei Zheng*, Ping Huang, Meiran Zhang, Wen Zhang, Zhonghua Deng, Shaohua Yu, Mengyao Jin, and Xueyuan Chen*, “Efficient Near-Infrared Luminescence in Lanthanide-Doped Vacancy-Ordered Double Perovskite Cs2ZrCl6 Phosphors via Te4+ Sensitization”, Angew. Chem. Int. Ed. 2022, 61, e202201993. DOI: 10.1002/anie.202201993 (featured as Hot Paper, 化学领域ESI高被引论文).
20. Zhongliang Gong, Wei Zheng*, Ping Huang, Xingwen Cheng, Wen Zhang, Meiran Zhang, Siyuan Han, and Xueyuan Chen*, “Highly efficient Sb3+ emitters in 0D cesium indium chloride nanocrystals with switchable photoluminescence through water-triggered structural transformation”, Nano Today 2022, 44, 101460. DOI: 10.1016/j.nantod.2022.101460 (Highlighted in News and opinions: “Lead-free metal halide nanocrystals light up”, Nano Today 2022, 45, 101540, July 2022; 物理领域ESI高被引论文).
21. Shilin Jin, Renfu Li*, Hai Huang, Naizhong Jiang, Jidong Lin, Shaoxiong Wang, Xueyuan Chen*, and Daqin Chen*, “Compact Ultra-Broadband Light-Emitting Diodes Based on Lanthanide Doped Lead-Free Double Perovskites”, Light Sci. Appl. 2022, 11, 52. DOI: 10.1038/s41377-022-00739-2 (物理领域ESI高被引和热点论文，Outstanding paper in 2023 for LSA；“Lanthanide doped lead-free double perovskites as the promising next generation ultra-broadband light sources”, highlighted in Light Sci. Appl. 2022, 11, 99. DOI: 10.1038/s41377-022-00782-z).
22. Yingjie Yang, Yan Liu*, Datao Tu, Mingmao Chen, Yunqin Zhang, Hang Gao, and Xueyuan Chen*, “Tumor-Microenvironment-Responsive Biodegradable Nanoagents Based on Lanthanide Nucleotide Self-Assemblies toward Precise Cancer Therapy”, Angew. Chem. Int. Ed. 2022, 61, e202116983. DOI: 10.1002/anie.202116983 (featured as Hot Paper).
23. Wei Zhang, Wei Zheng*, Lingyun Li*, Ping Huang, Zhongliang Gong, Ziwei Zhou, Jinyue Sun, Yan Yu, and Xueyuan Chen*, “Dual-Band-Tunable White-Light Emission from Bi3+/Te4+ Emitters in Perovskite-Derivative Cs2SnCl6 Microcrystals”, Angew. Chem. Int. Ed. 2022, 61, e202116085. DOI: 10.1002/anie.202116085 (featured as Hot Paper, 化学领域ESI高被引论文).
24. Xingwen Cheng, Zhi Xie, Wei Zheng*, Renfu Li, Zhonghua Deng, Datao Tu, Xiaoying Shang, Jin Xu, Zhongliang Gong, Xingjun Li, and Xueyuan Chen*, “Boosting the Self-Trapped Exciton Emission in Alloyed Cs2(Ag/Na)InCl6 Double Perovskite via Cu+ Doping”, Adv. Sci. 2022, 9, 2103724. DOI: 10.1002/advs.202103724. (物理领域ESI高被引论文)
25. Peng Zhang, Jianxi Ke, Datao Tu*, Jiayao Li, Yifan Pei, Le Wang, Xiaoying Shang, Shan Lu, Zhuo Chen, and Xueyuan Chen*, “Enhancing Dye-Triplet-Sensitized Upconversion Emission Through Heavy Atom Effect in CsLu2F7:Yb/Er Nanoprobes”, Angew. Chem. Int. Ed. 2022, 61, e202112125. DOI: 10.1002/anie.202112125.
26. Dan Xu, Jin Xu*, Xiaoying Shang, Shaohua Yu, Wei Zheng, Datao Tu, Renfu Li, and Xueyuan Chen*, “Boosting the Energy Migration Upconversion through Inter-Shell Energy Transfer in Tb3+-Doped Sandwich Structure Nanocrystals”, CCS Chem. 2022, 4, 2031-2042. DOI: 10.31635/ccschem.021.202101047.
27. Shaohua Yu, Jin Xu*, Xiaoying Shang, En Ma, Fulin Lin, Wei Zheng, Datao Tu, Renfu Li, and Xueyuan Chen*, “Unusual Temperature Dependence of Bandgap in 2D Inorganic Lead-Halide Perovskite Nanoplatelets”, Adv. Sci. 2021, 8, 2100084. DOI: 10.1002/advs.202100084.
28. Zhuo Li, Shan Lu*, Wenzhen Liu, Tao Dai, Jianxi Ke, Xingjun Li, Renfu Li, Yuxiang Zhang, Zhuo Chen, and Xueyuan Chen*, “Synergistic lysozyme-photodynamic therapy against resistant bacteria based on an intelligent upconversion nanoplatform”, Angew. Chem. Int. Ed. 2021, 60, 19201-19206. DOI: 10.1002/anie.202103943.
29. Jiaojiao Wei, Wei Zheng*, Ping Huang, Zhongliang Gong, Yan Liu, Shan Lu, Zhuo Li, and Xueyuan Chen*, “Direct Photoinduced Synthesis of Lead Halide Perovskite Nanocrystals and Nanocomposites”, Nano Today 2021, 39, 101179. DOI: 10.1016/j.nantod.2021.101179. (Highlighted in News and opinions: “Light touch has control over perovskite nanocrystals”, Nano Today 2021, 39, 101237, August 2021)
30. Yunqin Zhang, Xiyue Cheng, Datao Tu*, Zhongliang Gong, Renfu Li, Yingjie Yang, Wei Zheng, Jin Xu, Shuiquan Deng*, and Xueyuan Chen*, “Engineering the Bandgap and Surface Structure of CsPbCl3 Nanocrystals to Achieve Efficient Ultraviolet Luminescence”, Angew. Chem. Int. Ed. 2021, 60, 9693-9698. DOI: 10.1002/anie.202017370 (featured as Hot Paper).
31. Shanyong Zhou#, Datao Tu#, Yan Liu, Wenwu You, Yunqin Zhang, Wei Zheng, and Xueyuan Chen*, “Ultrasensitive Point-of-Care Test for Tumor Marker in Human Saliva Based on Luminescence-Amplification Strategy of Lanthanide Nanoprobes”, Adv. Sci. 2021, 8, 2002657. DOI: 10.1002/advs.202002657 (Highlighted in Wiley MaterialsViews China,“基于稀土纳米荧光探针实现唾液肿瘤标志物即时检测”, 2021.1.22).
32. Xiaorong Song, Shihua Li, Hanhan Guo, Wenwu You, Xiaoying Shang, Renfu Li, Datao Tu, Wei Zheng, Zhuo Chen, Huanghao Yang*, and Xueyuan Chen*, “Graphene Oxide Modified Lanthanide Nanoprobes for Tumor-Targeted Visible/NIR-II Luminescence Imaging”, Angew. Chem. Int. Ed. 2019, 58, 18981-18986. DOI: 10.1002/anie.201909416.
33. Hanhan Guo, Xiaorong Song*, Wen Lei, Cheng He, Wenwu You, Qingzhong Lin, Shanyong Zhou, Xueyuan Chen*, and Zhuo Chen*, “Direct Detection of Circulating Tumor Cells in Whole Blood Based on Time-Resolved Luminescent Lanthanide Nanoprobes”, Angew. Chem. Int. Ed. 2019, 58, 12195-12199. DOI: 10.1002/anie.201907605. (“Enhanced Glow: Direct detection of circulating tumor cells in blood samples”, highlighted in: Angew. Chem. Int. Ed. Press Release / Wiley.com Newsroom / ChemistryViews Magazine Bulletin, August 7, 2019. 入选2019年度中国稀土十大科技新闻)
34. Meiran Zhang, Wei Zheng*, Yan Liu, Ping Huang, Zhongliang Gong, Jiaojiao Wei, Yu Gao, Shanyong Zhou, Xingjun Li, and Xueyuan Chen*, “A new class of blue-LED-excitable NIR-II luminescent nanoprobes based on lanthanide-doped CaS nanoparticles”, Angew. Chem. Int. Ed. 2019, 58, 9556-9560. DOI: 10.1002/anie.201905040.
35. Zhongliang Gong, Wei Zheng*, Yu Gao, Ping Huang, Datao Tu, Renfu Li, Jiaojiao Wei, Wen Zhang, Yunqin Zhang, and Xueyuan Chen*, “Full-spectrum persistent luminescence tuning using all-inorganic perovskite quantum dots”, Angew. Chem. Int. Ed. 2019, 58, 6943-6947. DOI: 10.1002/anie.201901045 (“Full-color persistent luminescence tuning: A marriage of perovskite quantum dots and lanthanide ions”, highlighted in Sci. China Mater. 2019, DOI: 10.1007/s40843-019-1182-0).
36. Ping Huang, Wei Zheng*, Datao Tu, Xiaoying Shang, Meiran Zhang, Renfu Li, Jin Xu, Yan Liu, and Xueyuan Chen*, “Unraveling the electronic structures of neodymium in LiLuF4 nanocrystals for ratiometric temperature sensing”, Adv. Sci. 2019, 6, 1802282. DOI: 10.1002/advs.201802282 (物理领域ESI高被引论文).
37. Decai Huang, Haomiao Zhu*, Zhonghua Deng, Qilin Zou, Hongyu Lu, Xiaodong Yi, Wang Guo, Canzhong Lu, and Xueyuan Chen*, “Moisture-Resistant Mn4+-Doped Core-Shell Structured Fluoride Red Phosphor Exhibiting High Luminous Efficacy for Warm White LEDs”, Angew. Chem. Int. Ed. 2019, 58, 3843-3847. DOI: 10.1002/anie.201813363 (Hot paper).
38. Datao Tu, Wei Zheng, Ping Huang, and Xueyuan Chen*, “Europium-Activated Luminescent Nanoprobes: From Fundamentals to Bioapplications”, Coord. Chem. Rev. 2019, 378, 104-120. DOI: 10.1016/j.ccr.2017.10.027 (化学领域ESI高被引频次论文).
39. Wei Zheng, Ping Huang, Zhongliang Gong, Datao Tu, Jin Xu, Qilin Zou, Renfu Li, Wenwu You, Jean-Claude G. Bünzli, and Xueyuan Chen*, “Near-infrared-triggered photon upconversion tuning in all-inorganic cesium lead halide perovskite quantum dots”, Nat. Commun. 2018, 9, 3462. DOI: 10.1038/s41467-018-05947-2.
40. Jin Xu, Datao Tu, Wei Zheng, Xiaoying Shang, Ping Huang, Yao Cheng*, Yuansheng Wang, and Xueyuan Chen*, “Interfacial Defects Dictated In Situ Fabrication of Yolk-Shell Upconversion Nanoparticles by Electron-Beam Irradiation”, Adv. Sci. 2018, 5, 1800766. DOI: 10.1002/advs.201800766（入选2018中国稀土十大科技新闻、中科学海西研究院年度重大科技进展）.
41. Shenghan Zou, Yongsheng Liu*, Jianhai Li, Caiping Liu, Rui Feng, Feilong Jiang, Yongxiang Li, Jizhong Song, Haibo Zeng*, Maochun Hong*, and Xueyuan Chen*, “Stabilizing Cesium Lead Halide Perovskite Lattice through Mn (II)-Substitution for Air-Stable Light-Emitting Diodes”, J. Am. Chem. Soc. 2017, 139, 11443-11450. DOI: 10.1021/jacs.7b04000 (化学领域ESI高被引频次论文).
42. Yongsheng Liu, Shanyong Zhou, Zhu Zhuo, Renfu Li, Zhuo Chen, Maochun Hong*, and Xueyuan Chen*, “In-Vitro Upconverting/Downshifting Luminescent Detection of Tumor Markers Based on Eu3+-Activated Core-Shell-Shell Lanthanide Nanoprobes”, Chem. Sci. 2016, 7, 5013-5019. DOI: 10.1039/c6sc01195k (入选2016年中国稀土十大科技新闻；“Eu-activated dual-mode nano-bioprobes for in-vitro tumor marker detection”, highlighted in Research Results: Science Foundation in China 2016, 24(4), 6; 《中国科学报》2016-08-30 第4版)
43. Huajun He#, En Ma#, Yuanjing Cui#, Jiancan Yu, Yu Yang, Tao Song, Chuan-De Wu, Xueyuan Chen*, Banglin Chen*, and Guodong Qian*, “Polarized three-photon-pumped laser in a single MOF microcrystal”, Nat. Commun. 2016, 7, 11087. DOI: 10.1038/NCOMMS11087 (入选2016中国光学重要成果；物理领域ESI高被引频次论文; “Metal-organic framework microlasers”, highlighted in News & Views: Science Bulletin 2017, 62, 3-4).
44. Shan Lu, Datao Tu, Ping Hu, Jin Xu, Renfu Li, Meng Wang, Zhuo Chen, Mingdong Huang, and Xueyuan Chen*, “Multifunctional Nano-Bioprobes Based on Rattle-Structured Upconverting Luminescent Nanoparticles”, Angew. Chem. Int. Ed. 2015, 54, 7915-7919. DOI: 10.1002/anie.201501468.
45. Wei Zheng, Ping Huang, Datao Tu, En Ma, Haomiao Zhu, and Xueyuan Chen*, “Lanthanide-Doped Upconversion Nano-Bioprobes: Electronic Structures, Optical Properties, and Biodetection”, Chem. Soc. Rev. 2015, 44, 1379-1415. DOI: 10.1039/c4cs00178h (Inside Front Cover).（入选化学领域ESI高被引频次论文）
46. Shanyong Zhou, Wei Zheng, Zhuo Chen, Datao Tu, Yongsheng Liu, En Ma, Renfu Li, Haomiao Zhu, Mingdong Huang*, and Xueyuan Chen*, “Dissolution-Enhanced Luminescent Bioassay Based on Inorganic Lanthanide Nanoparticles”, Angew. Chem. Int. Ed. 2014, 53, 12498-12502. DOI: 10.1002/anie.201405937.（入选“2014年中国稀土十大科技新闻”）
47. Haomiao Zhu, Chun Che Lin, Wenqin Luo, Situan Shu, Zhuguang Liu, Yongsheng Liu, Jintao Kong, En Ma, Yongge Cao, Ru-Shi Liu*, and Xueyuan Chen*, “Highly efficient non-rare-earth red emitting phosphor for warm white light-emitting diodes”, Nature Commun. 2014, 5, 4312. DOI: 10.1038/NCOMMS5312. (入选2014中国光学重要成果；材料领域ESI高被引频次论文)
48. Ping Huang, Wei Zheng, Shanyong Zhou, Datao Tu, Zhuo Chen, Haomiao Zhu, Renfu Li, En Ma, Mingdong Huang, and Xueyuan Chen*, “Lanthanide-Doped LiLuF4 Upconversion Nanoprobes for the Detection of Disease Biomarkers”, Angew. Chem. Int. Ed. 2014, 53, 1252-1257. DOI: 10.1002/anie.201309503. (Hot paper, featured as Frontispiece) （入选化学领域ESI高被引频次论文）
49. Yongsheng Liu, Datao Tu, Haomiao Zhu, and Xueyuan Chen*, “Lanthanide-Doped Luminescent Nanoprobes: Controlled Synthesis, Optical Spectroscopy, and Bioapplications”, Chem. Soc. Rev. 2013, 42, 6924-6858. DOI: 10.1039/C3CS60060B.（入选化学领域ESI高被引频次论文）
50. Wei Zheng, Shanyong Zhou, Zhuo Chen, Ping Hu, Yongsheng Liu, Datao Tu, Haomiao Zhu, Renfu Li, Mingdong Huang, and Xueyuan Chen*, “Sub-10 nm Lanthanide-Doped CaF2 Nanoprobes for Time-Resolved Luminescent Biodetection”, Angew. Chem. Int. Ed. 2013, 52, 6671-6676. DOI: 10.1002/ANIE.201302481.
51. Qingdong Zheng*, Haomiao Zhu, Shan-Ci Chen, Changquan Tang, En Ma, and Xueyuan Chen*, “Frequency-upconverted stimulated emission by simultaneous five-photon absorption”, Nature Photonics 2013, 7, 234-239. DOI: 10.1038/NPHOTON.2012.344. (入选2013中国光学重要成果)
52. Datao Tu, Yongsheng Liu, Haomiao Zhu, Renfu Li, Liqin Liu, and Xueyuan Chen*, “Breakdown of Crystallographic Site Symmetry in Lanthanide-Doped NaYF4 Crystals”, Angew. Chem. Int. Ed. 2013, 52, 1128-1133. DOI: 10.1002/ANIE.201208218.（入选化学领域ESI高被引频次论文）
53. Yongsheng Liu, Shanyong Zhou, Datao Tu, Zhuo Chen, Mingdong Huang, Haomiao Zhu, En Ma, and Xueyuan Chen*, “Amine-Functionalized Lanthanide-Doped Zirconia Nanoparticles: Optical Spectroscopy, Time-Resolved Fluorescence Resonance Energy Transfer Biodetection and Targeted Imaging”, J. Am. Chem. Soc. 2012, 134, 15083-15090. DOI: 10.1021/JA306066A. (“Tiny, Brightly Glowing Nanoparticles Could Detect Disease Biomarkers” in: Chemical & Engineering News, September 5, 2012; “Lanthanide Biological Probe on a ZrO2 Nanoparticle Host”, highlighted in JACS Spotlights, 2012, Vol.134, No.39, p.16093. 入选化学领域ESI高被引频次论文)
54. Qiang Ju, Datao Tu, Yongsheng Liu, Renfu Li, Haomiao Zhu, Jincan Chen, Zhuo Chen, Mingdong Huang, and Xueyuan Chen*, “Amine-Functionalized Lanthanide-Doped KGdF4 Nanocrystals as Potential Optical/Magnetic Multimodal Bioprobes”, J. Am. Chem. Soc. 2012, 134, 1323-1330. DOI: 10.1021/JA2102604.（入选化学领域ESI高被引频次论文和2012年最热门中国研究论文50强）
55. Datao Tu, Liqin Liu, Qiang Ju, Yongsheng Liu, Haomiao Zhu, Renfu Li and Xueyuan Chen*, “Time-Resolved FRET Biosensor Based on Amine-Functionalized Lanthanide-Doped NaYF4 Nanocrystals”, Angew. Chem. Int. Ed. 2011, 50, 6306-6310. DOI: 10.1002/ANIE.201100303.（入选化学领域ESI高被引频次论文）
56. Yongsheng Liu, Datao Tu, Haomiao Zhu, Renfu Li, Wenqin Luo, and Xueyuan Chen*, “A Strategy to Achieve Efficient Dual-Mode Luminescence of Eu3+ in Lanthanides Doped Multifunctional NaGdF4 Nanocrystals”, Adv. Mater. 2010, 22, 3266-3271. DOI: 10.1002/ADMA.201000128.（入选材料领域ESI高被引频次论文，2010中国光学重要成果，2012福建省自然科学优秀学术论文一等奖）

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