谢建武

男， 金华高等研究院， 教授/研究员/教授级高工或同等级别

学习/工作经历

1997/09-2001/07，广西师范大学，化学与药学学院，化学教育，学士
2001/09-2004/07，广西师范大学，化学与药学学院，有机化学，硕士
2004/09-2007/07，中国科学院成都有机所，有机化学，博士
2007/04–2008/04，日本京都大学，药学部，COE研究员
2008/07-2020.12，浙江师范大学，化学与生命科学学院，教授
2021.01-至今 陕西科技大学，药学系，教授

研究领域和兴趣

有机合成、不对称合成、药物合成

主要业绩

主要研究方向为1. 药物及其中间体合成技术的研发；2. 新型催化剂的设计与合成及其在不对称合成中的应用；3. 杂环化合物的合成研究；目前在国内外学术期刊Angew. Chem. Int. Ed.、Chem.Commun.、Org. Lett.、J. Org. Chem.、Tetrahedron Lett.、Org. Biomol. Chem.、Adv. Synth. Catal.和Tetrahedron上发表论文60余篇，论文他引超过800次，单篇他引大于200次；是国际期刊"Chem. Soc. Rev." "Chem. Commun." "J. Org. Chem." "Adv. Synth. Catal." "Org. Biomol. Chem." "Tetrahedron Lett." "Tetrahedron"等十几种期刊的审稿专家。主持国家自然科学基金项目2项，重点教改项目1项，省部级及企业合作项目多项，授权专利16项，转让2项。先后获得“中国科学院院长优秀奖”、“中国科学院西部学子奖”、“浙江省科学技术奖”、浙江省“151人才工程”等荣誉称号。

代表成果

1. P. Gong, J. W, W.-B. Yao, X.-S. Xie, J.-W. Xie*, Diastereoselective and Enantioselective Formal [4 + 1] Ylide Annulation Leading to Optically Active Isoxazoline N-oxides, Adv. Synth. Catal., 2022, 364(6), 1185-1199. DOI: 10.1002/adsc.202101474
2. L.-J. Chen, J.-H. Yu, B. He, J.-W. Xie, Y.-X. Liu, and W.-D. Zhu, Umpolung Strategy for the Synthesis of Chiral Dispiro[2-amino-4,5-dihydrofuran-3-carbonitrile]bisoxindoles, J. Org. Chem. 2020, 85, 7793−7802. DOI: 10.1021/acs.joc.0c00418
3. L.-S.-H. Yu, J. Wang, Z.-J. Gao, J.-W. Xie, Substrate-Controlled Diastereoselectivity Switch in the Formation of Dihydrothiophene Derivatives via [4+1] Annulations, Adv. Synth. Catal., 2019, 361, 526-534. DOI: 10.1002/adsc.201801104
4. J.-L Dong, P.-S. Wei, L.-S.-H. Yu, J.-W. Xie*, Chemoselective Synthesis of Structurally Diverse 3,4-dihydroquinazoline-2(1H)-thiones and 4H-benzo[d][1,3]thiazines J. Org. Chem. 2018, 83, 2219-2226. DOI: 10.1021/acs.joc.7b03120
5. X.-N. Ping, P.-S. Wei, X.-Q. Zhu, J.-W. Xie*, Catalyst-Controlled Switch in Diastereoselectivities: Enantioselective Construction of Functionalized 3,4-Dihydro-2H-thiopyrano[2,3-b]quinolines with Three Contiguous Stereocenters, J. Org. Chem. 2017, 82, 2205-2210. DOI: 10.1021/acs.joc.6b02688
6. X.-M. Zeng, J.-W. Xie*, Enantioselective Synthesis of Ring-Fused Spiroannulated 1,2,3-Thiadiazole Derivatives, J. Org. Chem. 2016, 81, 3553–3559. DOI: 10.1021/acs.joc.6b00127
7. P.-S. Wei, M.-X., Wang, D.-C. Xu and J.-W. Xie*, Synthesis of 2,3-Dihydrothieno(2,3‑b)quinolines and Thieno(2,3‑b)-quinolines via an Unexpected Domino Aza-MBH/Alkylation/Aldol Reaction, J. Org. Chem. 2016, 81(3), 1216–1222. DOI: 10.1021/acs.joc.5b02369
8. X.-M. Zeng, C.-Y. Meng, J.-X. Bao, D.-C. Xu, J.-W. Xie* and W.-D. Zhu, Enantioselective Construction of Polyfunctionalized Spiroannulated Dihydrothiophenes via a Formal Thio [3 + 2] Cyclization, J. Org. Chem. 2015, 80, 11521-11528. DOI: 10.1021/acs.joc.5b01357
9. J.-W. Xie*, M.-L. Xu, R.-Z. Zhang, J.-Y. Pan and W.-D. Zhu*, Organocatalytic Domino Reaction of Electron-Deficient 2,4-Dienes with 2-Halo-1,3-Dicarbonyl Compounds: A Highly Regio- and Stereoselective Approach to Functionalized Five-Membered Carbocycles, Adv. Synth. Catal., 2014, 356, 395-400. DOI: 10.1002/adsc.201300788
10. J.-W. Xie, W. Chen, R. Li, M. Zeng, W. Du, L. Yue, Y.-C. Chen*, Y. Wu, J. Zhu, and J.-G. Deng*, Highly Asymmetric Michael addition of ,-Unsaturated Ketones Catalyzed by 9-Amino-9-deoxyepiquinine, Angew. Chem. Int. Ed, 2007, 46, 389-392. DOI: 10.1002/anie.200603612

*以上信息由高级会员个人更新和维护。