郭成

男， 浙江大学， 副教授/副研究员/高级工程师或同等级别

学习/工作经历

1.教育经历：
2004/09-2008/06，华中科技大学化学与化工学院，学士
2006/02-2008/06，武汉大学生命科学学院，学士（双学位）
2008/09-2013/06，浙江大学化学系，博士

2.研究工作经历：
2013/08-至今，浙江大学，助理研究员、副研究员

研究领域和兴趣

质谱分析，核酸修饰分析，代谢组学，精准医学分析

主要业绩

近年来以第一或通讯作者在Analytical Chemistry, Journal of Hazardous Materials, Chinese Chemical Letters, Analytica Chimica Acta, Journal of Proteome Research, Journal of the American Society for Mass Spectrometry等期刊上发表SCI论文40余篇，以合作作者身份在Nature，JACS等期刊发表SCI论文多篇。主持国家自然科学基金面上项目、青年基金、浙江省重点研发计划等科研项目9项，授权发明专利3项，相关研究成果获浙江省分析测试科学技术奖。担任中国分析测试协会质谱专业委员会、青年学术委员会、生命组学专业委员会委员，浙江省分析测试协会色谱质谱专业委员会委员及青委会副主任委员，Chinese Chemical Letters, Journal of Analysis and Testing期刊青年编委。

代表成果

近5年以第一作者或通讯作者发表的部分论文：
(1) Cheng Guo*, Xiujuan Hong, Yiqiu Hu, Tao Pan, Yunxiang Zhou, Haifen Lei, Yuanjiang Pan*. A highly sensitive and high-throughput quantitative HILIC-MS/MS method for systematic profiling of RNA modifications. Analytical Chemistry, 2026, 98, 4886-4894.
(2) Qianqian Chen, Ziheng Xu, Jiayi Mu, Xiujuan Hong, Yanqin Huang, Jiekai Yu, Ying Yuan, Ning Zhu*, Cheng Guo*. Urine metabolic profiling and discovery of potential biomarkers for colorectal cancer using liquid chromatography-mass spectrometry. Chinese Chemical Letters, 2026, 37, 112327.
(3) Zhongyan Zhou, Donghao Li, Na Wang, Xiujuan Hong, Wen Su, Cheng Guo*, Chongsheng He*, Lei Yue*. Comprehensive analysis of metabolic response in Arabidopsis thaliana under heavy metal stress by mass spectrometry. Journal of Hazardous Materials, 2026, 502, 140616.
(4) Keqiang Shi, Xiujuan Hong, Dongyan Xu, Tao Pan, Huiwen Wang, Hongru Feng, Cheng Guo*, Yuanjiang Pan*. Analysis of RNA modifications in peripheral white blood cells from breast cancer patients by mass spectrometry. Chinese Chemical Letters, 2025, 36, 110079.
(5) Xiaoji Cao*, Mingwei Wang, Yanqin Huang, Mengwen Zhang, Fengjin Zheng, Genyin Zhang, Jiaming Su, Ying Yuan, Cheng Guo*. Determination of dimethylated nucleosides in serum from colorectal cancer patients by hydrophilic interaction liquid chromatography-tandem mass spectrometry. Journal of Chromatography B, 2024, 1232, 123973.
(6) Cheng Guo*, Xiaoxiao Zhang, Xiujuan Hong, Yiqiu Hu, Lingna Mao, Kezhi Jiang*. Graphene as adsorbent for highly efficient extraction of modified nucleosides in urine prior to liquid chromatography-tandem mass spectrometry analysis. Chinese Chemical Letters, 2024, 35, 108867.
(7) Yiqiu Hu, Xiujuan Hong, Zhijun Yuan, Jiayi Mu, Xiaoxiao Zhang, Zhihao Fang, Ying Yuan, Shu Zheng, Cheng Guo*. Pan-cancer analysis of DNA epigenetic modifications by hydrophilic interaction liquid chromatography-tandem mass spectrometry. Chinese Chemical Letters, 2023, 34, 108023.
(8) Ge Ma, Xiaoyong Zhao, Mengzhe Guo, Yaqin Liu, Keqiang Shi, Cheng Guo*, Yuanjiang Pan*. 6-Glycosylaminoquinoline-assisted LDI MS for detection and imaging of small molecules with enhanced detection selectivity and sensitivity. Analytica Chimica Acta, 2022, 1201, 339620.
(9) Rongrong Huang, Kexin Shen, Quan He, Yiqiu Hu, Cuirong Sun*, Cheng Guo*, Yuanjiang Pan*. Metabolic profiling of urinary chiral amino-containing biomarkers for gastric cancer using a sensitive chiral chlorine-labeled probe by HPLC-MS/MS. Journal of Proteome Research, 2021, 20, 3952-3962.
(10) Cheng Guo*, Yiqiu Hu, Xiaoji Cao, Yinsheng, Wang*. HILIC-MS/MS for the Determination of Methylated Adenine Nucleosides in Human Urine. Analytical Chemistry, 2021, 93, 17060-17068.

*以上信息由高级会员个人更新和维护。