韩益丰

男， 浙江理工大学化学系， 教授/研究员/教授级高工或同等级别

学习/工作经历

1997.09-2001.06 兰州大学 学士 化学
2001.09-2006.06 兰州大学 博士 有机化学
2006.07-2012.12 浙江理工大学 副教授
2013.01-2014.01 美国哈佛大学 访问学者
2014.02-至今 浙江理工大学 教授

研究领域和兴趣

荧光染料和荧光探针

主要业绩

韩益丰，博士，教授，浙江省化学会会员，浙江省毒理学会纳米毒理学委员会理事，主要从事有机荧光染料和有机小分子荧光探针的设计合成及其在生物医学和环境检测等领域中的应用。目前已主持国家自然科学基金一项，浙江省自然科学基金两项，浙江省育才工程项目一项，企业合作项目多项，并作为主要人员参与了多项国家自然科学基金和浙江省自然科学基金的项目。目前已建立了对生物巯基物种、活性氧化物种、甲醛以及重金属离子等待测物的快速、灵敏的检测方法，相关工作在Theranostics，Organic Letters，Biosensors and Bioelectronics，Sensors and Actuators B等国际著名期刊上发表，在小分子荧光探针领域进行了大量的原创性研究工作。近五年来，以通讯作者或（和）第一作者发表SCI收录论文二十余篇，申请国家发明专利12项，已获授权6项，在有机小分子荧光探针领域取得了一定的成果。

代表成果

[1] Cheng Bao, Sufang Shao, Haifeng Zhou, Yifeng Han,* A new ESIPT-based fluorescent probe for the highly sensitive detection of amine vapors, New Journal of Chemistry, 45(2021), 10735, https://doi.org/10.1039/D1NJ01826D.
[2] Yu Ding, Yimin Pan, Yifeng Han,* A Coumarin-Based Fluorescent Probe for Ratiometric Mo nitoring of Hg2+ in Live Cells, Industrial & Engineering Chemistry Research, 58(2019), 7786, https://doi.org/10.1021/acs.iecr.9b00987.
[3] Jing Huang, Bo Chen, Baocheng Zhou, Yifeng Han,* A novel ESIPT-based fluorescent chemodosimeter for Hg2+ detection and its application in live-cell imaging, New Journal of Chemistry, 42(2018), 1181, https://doi.org/10.1039/C7NJ03789A.
[4] Bo Chen, Jing Huang, Huiqing Geng, Lingli Xuan, Tengfei Xu, Xin Li, Yifeng Han,* A new ESIPT-based fluorescent probe for highly selective and sensitive detection of hydrogen sulfide and its application in live-cell imaging, New Journal of Chemistry, 41(2017), 1119, https://doi.org/10.1039/C6NJ03355E.
[5] Yu Chen, Bo Chen, and Yifeng Han,* A novel rhodamine-based fluorescent probe for the fluorogenic andchromogenic detection of Pd2+ ions and its application in live-cellimaging, Sensors and Actuators B: Chemical, 237(2016), 1, https://doi.org/10.1016/j.snb.2016.06.067.
[6] Ting Wei, Jinglu Wang, Yu Chen and Yifeng Han,* Combining PeT and ICT Mechanism into One Chemosensor for the Highly Sensitive and Selective Detection of Zinc, RSC Advances, 5(2015), 57141, https://doi.org/10.1039/C5RA11194C.
[7] Xin Li, Chengyu Yang, Kai Wu, Yongzhou Hu, Yifeng Han,* Steven H. Liang,* A Highly Specific Probe for Sensing Hydrogen Sulfide in Live Cells Based on Copper-Initiated Fluorogen with Aggregation-Induced Emission Characteristics, Theranostics, 4(2014), 1233, https://doi.org/10.7150/thno.10330.
[8] Yifeng Han, Yun Ma, Ivan Keresztes, David B. Collum,* E. J. Corey,* Preferential Geminal Bis-silylation of 3, 4-Benzothiophane Is Caused by the Dominanc, Organic Letters, 16(2014), 4678, https://doi.org/10.1021/ol502348y.
[9] 韩益丰；陈波；魏婷；一种检测甲醛的荧光探针及其制备方法与应用；申请年份2016，申请号201610077333.3；批准年份2018，专利号CN201610077333.3.
[10] 韩益丰；包诚；丁钰；章世深；一种检测亚硝酸根离子荧光探针及其制备方法与使用方法；申请年份2019，申请号201910807550.7；批准年份2021，专利号CN201910807550.7.

*以上信息由高级会员个人更新和维护。