翟红林

男， 兰州大学化学化工学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

1982.09-1986.09 兰州大学化学系，本科生
2001.09-2004.12 兰州大学化学化工学院，博士研究生

1986.07-1993.04 兰州大学应用有机化学国家重点实验室，教师
1993.05-今 兰州大学化学化工学院，教师
2007.01-2008.01 台湾长庚大学分子医学中心，博士后

研究领域和兴趣

化学与生物信息学

主要业绩

1. 首次提出并发展了化学矩方法，已在HPLC、HPLC-DAD、LC-MS、CD、IR、NIR、UV、NMR、Flour、3D Flour等多种化学图谱在复杂样品中多组分同时定性定量分析中获得成功应用。
2. 采用分子模拟技术开展了蛋白结构特征分析、药物与蛋白相互作用、纳米材料生物特性等研究

代表成果

1. R. R. Liu, H. L. Zhai*, Y. J. Meng, M. Zhu, T. Wen, N. Z. Jin. Adsorption behaviors of typical proteins on BP, GR and C2N surfaces. Journal of Chemical Information and Modeling, 2021, 61(3): 1300-1306.
2. B. Yin, H. L. Zhai*, B. Q. Zhao, K. X. Bi, J. Y. Mi. Chemometrics-assisted simultaneous voltammetric determination of multiple neurotransmitters in human blood serum. Bioelectrochemistry, 2021, 139: 107739.
3. Y. J. Meng, R. R. Liu, M. Zhu, H. L. Zhai*, C. L. Ren. Potential toxicity mechanism of MoS2 nanotube in the interaction between YAP65 WW domain and PRM. Colloids and Surfaces B: Biointerfaces, 2020, 196C: 111317.
4. S. H. Lu, H. L. Zhai*, B. Q. Zhao, B. Yin, L. Zhu. Novel approach to the analysis of chemical third-order data. Journal of Chemical Information and Modeling, 2020, 60(10): 4750-4756.
5. B. Yin, R. R. Liu, H. L. Zhai*, S. H. Lu, J. Y. Mi. One-pot facile synthesis of CuNCs/RGO nanocomposite for the sensitive detection of heparin in human serum samples. Talanta, 2020, 213: 120838.
6. M. Zhu, H. L. Zhai*, Y. J. Meng, L. Han, C. L. Ren. The binding mechanism of nitroreductase fluorescent probe: Active pocket deformation and intramolecular hydrogen bonds. International Journal of Biological Macromolecules, 2020, 150: 509-518.
7. B. Yin, S. S. Li, S. H. Lu, J. Y. Mi, H. L. Zhai*. Simultaneous quantification of multiple endogenous biothiols in cancer cell based on multi-signal fluorescent probe. Analyst, 2019, 144(15): 4575-4581.
8. S. H. Lu, S. S. Li, B. Yin, J. Y. Mi, H. L. Zhai*. The rapid quantitative analysis of three pesticides in cherry tomatoes and red grape samples with Tchebichef image moments. Food Chemistry, 2019, 290: 72-78.
9. H. L. Zhai*, B. Q. Li, J. Chen, X. Wang, M. L. Xu, J. J. Liu, S. H. Lu. Chemical image moments and their applications. TrAC-Trends in Analytical Chemistry, 2018, 103: 119-125.
10. B. Q. Li, M. L. Xu, X. Wang, H. L. Zhai*, J. Chen, Jin Jin Liu. An approach to the simultaneous quantitative analysis of metabolites in table wines by 1H NMR self-constructed three-dimensional spectra. Food Chemistry, 2017, 216: 52-59.

*以上信息由高级会员个人更新和维护。