贺晓鹏

男， 华东理工大学，化学与分子工程学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

2014.09—至今，华东理工大学，化学与分子工程学院，教授，博士生导师
2013.06—2014.08，华东理工大学，化学与分子工程学院，讲师
2011.07—2013.06，华东理工大学，化学与分子工程学院，博士后（师从：陈凯先 院士）
2006.09—2011.06，华东理工大学，制药工程与技术，工学博士（师从：施小新 教授、龙亿涛 教授）
2008.07—2009.02，法国Cachan高等师范学校，生物有机，联合培养（师从：Juan Xie教授）
2002.09—2006.06，华东理工大学，应用化学，学士

研究领域和兴趣

糖化学生物学、分析化学

主要业绩

本人长期从事疾病关联生物大分子靶向识别与功能调控的分子探针创制工作，开拓了以光活性标签修饰天然生物配体（如糖类与肽类）引导分子自组装，从而构建“控制激活型”生物（大）分子探针的独特化学生物学研究策略，坚持以临床需求为导向，在疾病相关生物分子本征动态属性的细胞原位探测（诊）与功能调控（疗）领域形成了鲜明的交叉学科研究特色。2015年来代表性论文包括1篇Sci. Bull., 3篇J. Am. Chem. Soc., 3篇Angew. Chem. Int. Ed., 1篇 Nat. Commun., 1篇Chem, 5篇Chem. Sci.和5篇Chem. Soc. Rev.，所有论文他引2343次（H因子33），ESI高被引论文11篇。获中国化学会青年化学奖、中国化学会化学生物学突出贡献奖（35周岁以下）、Thieme Chemistry Journals Award，担任《科学通报》与《高等学校化学学报》化学生物学专区青年编委。拟聚焦原创性动态荧光探针原位解译疾病演进过程的基础研究与临床应用。

代表成果

1. Jin-Biao Jiao†, Guan-Zhen Wang†, Xi-Le Hu†, Yi Zang, Stéphane Maisonneuve, Adam C. Sedgwick, Jonathan L. Sessler*, Juan Xie*, Jia Li*, Xiao-Peng He*, He Tian, Cyclodextrin-based peptide self-assemblies (Spds) that enhance peptide-based fluorescence imaging and antimicrobial efficacy. J. Am. Chem. Soc. 2020, 142, 1925.
2. Adam C. Sedgwick†, Wei-Tao Dou†, Jin-Biao Jiao, Luling Wu, George T. Williams, A. Toby A. Jenkins, Steven D. Bull, Jonathan L. Sessler*, Xiao-Peng He*, Tony D. James*, An ESIPT probe for the ratiometric imaging of peroxynitrite facilitated by binding to Aβ-aggregates. J. Am. Chem. Soc. 2018, 140, 14267.
3. Youxin Fu†, Hai-Hao Han†, Junji Zhang*, Xiao-Peng He*, Ben L. Feringa, He Tian*, Photocontrolled fluorescence “double-check” bioimaging enabled by a glycoprobe−protein hybrid. J. Am. Chem. Soc. 2018, 140, 8671.
4. Junji Zhang, Youxin Fu, Hai-Hao Han, Yi Zang, Jia Li*, Xiao-Peng He*, Ben L. Feringa, He Tian*, Remote light-controlled intracellular target recognition by photochromic fluorescent glycoprobes. Nat. Commun. 2017, 8, 987 (ESI highly cited paper).
5. Adam C. Sedgwick, Wei-Tao Dou, Jin-Biao Jiao, Luling Wu, George T. Williams, A. Toby A. Jenkins, Steven D. Bull, Jonathan L. Sessler*, Xiao-Peng He*, and Tony D. James*. An ESIPT Probe for the Ratiometric Imaging of Peroxynitrite Facilitated by Binding to Aβ-Aggregates. J. Am. Chem. Soc. 2018, 140, 14267−14271.
6. Xiao-Peng He, He Tian*. “Lightening up membrane receptors with fluorescent molecular probes and supramolecular materials.” Chem 2018, 4, 246-268.
7. Yinjuan Huang, Wei-Tao Dou, Fugui Xu, Hong-Bo Ru, Qiuyu Gong, DongqingWu, Deyue Yan, He Tian, Xiao-Peng He*, Yiyong Mai*, and Xinliang Feng. Supramolecular Nanostructures of Structurally Defined Graphene Nanoribbons in the Aqueous Phase. Angew. Chem. Int. Ed. 2018, 57, 1-7.
8. Adam C. Sedgwick, Luling Wu, Hai-Hao Han, Steven D. Bull*, Xiao-Peng He*, Tony D. James*, Jonathan L. Sessler*, Ben Zhong Tang*, He Tian * and Juyoung Yoon*. Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents. Chem. Soc. Rev. 2018,47, 8842-8880.
9. Xiao-Peng He*, Xi-Le Hu, Tony D. James*, Juyoung Yoon * and He Tian*. Multiplexed photoluminescent sensors: towards improved disease diagnostics. Chem. Soc. Rev. 2017, 46, 6687-6696.
10. Xiao-Peng He*, Ya-Li Zeng, Xin-Ying Tang, Na Li, Dong-Ming Zhou*, Guo-Rong Chen, He Tian*. “Rapid identification of the receptor-binding specificity of influenza A viruses by fluorogenic glycofoldamers.” Angew. Chem. Int. Ed. 2016, 55, 13995-13999.

*以上信息由高级会员个人更新和维护。