杨盛

男， 湖南师范大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

2002.09-2006.06，湖南大学，化学， 本科
2006.07-2007.08，上海睿智化学研究有限公司
2008.09-2010.09，湖南大学，有机化学， 硕士
2010.09-2014.12，湖南大学，分析化学，博士
2015.04-2021.08，长沙理工大学，化学与食品工程学院，讲师/副教授
2021.09-2023.12，湖南师范大学，化学化工学院，副教授
2022.09-2023.08，新加坡南洋理工大学，访问学者
2024.01-至今，湖南师范大学，化学化工学院，教授

研究领域和兴趣

适用于复杂生物体系的荧光传感放大及高灵敏生物成像；亚细胞荧光传感与细胞器动态限域分析；多组分串联激活荧光传感与疾病精准诊断/污染危害解析；自噬相关生物传感与功能调控

主要业绩

主要从事化学测量学-化学生物传感研究，期望发展适用于生物复杂体系和亚细胞层面的光学传感与生物成像新原理与新技术并应用于疾病精准诊断治疗、环境污染生物危害解析与预警、中药材功能鉴别与活性成分筛选。迄今已在Angew Chem Int Ed, Small, Anal Chem, ACS Sens等期刊发表第一/通讯作者论文30余篇，授权国家发明专利3项。先后主持承担国家自然科学基金3项，湖南省自然科学基金2项。获2019年度湖南省自然科学一等奖（排名第2）。入选2022年度湖南省科技人才托举工程项目-中青年学者。

代表成果

[1] Yibo Zhou, Sheng Yang*, Zhihe Qing*, Ronghua Yang*, et al A Polymeric Nanobeacon for Monitoring the Fluctuation of Hydrogen Polysulfides During Fertilization and Embryonic Development, Angewandte Chemie International Edition, 2022, 61(16): e202114504
[2] Siya Chen, Sheng Yang*, Jing Zheng*, et al Design and Engineering of Hypoxia and Acidic pH Dual-Stimuli-Responsive Intelligent Fluorescent Nanoprobe for Precise Tumor Imaging, Small, 2021, 17(28): 2100243
[3] Xiao Liu, Sheng Yang*, Lin Yuan*, et al Dual-Stimulus Responsive Near-Infrared Reversible Ratiometric Fluorescent and Photoacoustic Probe for In Vivo Tumor Imaging, Analytical Chemistry, 2021, 93(13): 5420−5429
[4] Yibo Zhou, Sheng Yang*, Ronghua Yang*, et al Long-Lasting Bioluminescence Imaging of the Fibroblast Activation Protein by an Amphiphilic Block Copolymer-Based Probe, Analytical Chemistry, 2021, 93(8): 3726−3732
[5] Sheng Yang, Ronghua Yang*, et al Substrate-Photocaged Enzymatic Fluorogenic Probe Enabling Sequential Activation for Light-Controllable Monitoring of Intracellular Tyrosinase Activity, Analytical Chemistry, 2020, 92(10): 7194−7199
[6] Yibo Zhou, Sheng Yang*, Ronghua Yang*, et al In Vivo Imaging of Hypoxia Associated with Inflammatory Bowel Disease by Cytoplasmic Protein-Powered Fluorescence Cascade Amplifier, Analytical Chemistry, 2020, 92(8): 5787−5794
[7] Jinqiu Luo, Sheng Yang*, Ronghua Yang*, et al Noncovalently Caged Firefly Luciferins Enable Amplifiable Bioluminescence Sensing of Hyaluronidase-1 Activity In Vivo, ACS Sensors, 2020, 5(6): 1726−1733
[8] Yibo Zhou, Sheng Yang*, Ronghua Yang*, et al Cytoplasmic Protein-Powered In Situ Fluorescence Amplification for Intracellular Assay of Low-Abundance Analyte, Analytical Chemistry, 2019, 91(23): 15179−15186
[9] Yuan Li, Sheng Yang*, Ronghua Yang*, et al Differentiation of Intracellular Hyaluronidase Isoform by Degradable Nanoassembly Coupled with RNA-Binding Fluorescence Amplification, Analytical Chemistry, 2019, 91(10): 6887−6893
[10] Sheng Yang, Ronghua Yang*, et al Visualizing Endogenous Sulfur Dioxide Derivatives in Febrile-Seizure-Induced Hippocampal Damage by a Two-Photon Energy Transfer Cassette, Analytical Chemistry, 2018, 90(24): 14514−14520

*以上信息由高级会员个人更新和维护。