魏东辉

男， 郑州大学化学学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

2022.02—至今 郑州大学化学学院 教授
2017.01—2022.02 郑州大学化学学院 副教授
2013.01—2016.12 郑州大学化学与分子工程学院 讲师
2010.10—2012.11 美国肯塔基大学药学院 国家公派联合培养博士
2006.09—2012.12 郑州大学化学分子与工程学院 博士
2002.09—2006.07 郑州大学化学系 本科

研究领域和兴趣

理论与计算化学

主要业绩

曾先后获批国家自然科学基金-青年基金项目和面上项目各1项、中国博士后科学基金面上资助和特别资助各1项、2021年河南省自然科学基金-优秀青年科学基金项目，入选2020年河南省高等学校青年骨干教师、郑州大学青年拔尖人才、郑州大学优秀青年教师等培养计划。博士毕业论文被评为“河南省优秀博士学位论文”，曾获得“河南省优秀硕士学位论文指导教师”称号。长期围绕有机催化反应（尤其是氮杂环卡宾催化反应）和生物酶催化及抑制反应的机理及其选择性进行理论计算研究工作。近年来，以第一或通讯作者的身份在J. Am. Chem. Soc. (3)、Angew. Chem. Int. Ed. (2)、Nature Commun. (2)、Coord. Chem. Rev. (1)、ACS Catal. (7)、Chem. Sci. (2)等杂志上正式发表论文139篇。

代表成果

1. Qianqian Shi, Zhipeng Pei, Jinshuai Song, Shi-Jun Li, Donghui Wei*, Michelle L. Coote*, Yu Lan*, Diradical Generation via Relayed Proton-Coupled Electron Transfer, J. Am. Chem. Soc., 2022, 144(7), 3137-3145, 10.1021/jacs.1c12360.
2. Junjian Wang, Donghui Wei*, Zheng Duan*, and Francois, Mathey Cleavage of the Inert C(sp2)-Ar σ Bond of Alkenes by a Spatial Constrained Interaction with Phosphinidene, J. Am. Chem. Soc., 2020, 142(50), 20973-20978, 10.1021/jacs.0c11195.
3. Donghui Wei, Beilei Lei, Mingsheng Tang, Chang-Guo Zhan*, Fundamental Reaction Pathway and Free Energy Profile for Inhibition of Proteasome by Epoxomicin, J. Am. Chem. Soc., 2012, 134(25), 10436-10450, 10.1021/ja3006463.
4. Simiao Zhang, Xiaoxue Wang, Li-Li Han, Jibin Li, Zheng Liang, Donghui Wei*, Ding Du*, Atroposelective Synthesis of Triaryl α-Pyranones with 1,2-Diaxes by N-Heterocyclic Carbene Organocatalysis, Angew. Chem. Int. Ed., 2022, 61(52), e202212005, 10.1002/anie.202212005.
5. Guanjie Wang, Qiao-Chu Zhang, Chenlong Wei, Ye Zhang, Linxue Zhang, Juhui Huang, Donghui Wei*, Zhenqian Fu*, and Wei Huang, Asymmetric Carbene-Catalyzed Oxidation of Functionalized Aldimines as 1,4-Dipoles, Angew. Chem. Int. Ed., 2021, 60(14), 7913-7919, 10.1002/anie.202017017.
6. Zhouli Hu, Chenlong Wei, Qianqian Shi, Xianfang Hong, Jinhua Liu, Xiangui Zhou, Jinna Han, Wei Cao, Ashis Kumar Gupta, Xiaoxiang Zhang, Donghui Wei*, Zhenqian Fu*, Wei Huang, Desymmetrization of N-Cbz glutarimides through N-heterocyclic carbene organocatalysis, Nat. Commun., 2022, 13, 4042, 10.1038/s41467-022-31760-z.
7. Guanjie Wang, Qianqian Shi, Wanyao Hu, Tao Chen, Yingying Guo, Zhouli Hu, Minghua Gong, Jingcheng Guo, Donghui Wei*, Zhenqian Fu* and Wei Huang*, Organocatalytic asymmetric N-sulfonyl amide C-N bond activation to access axially chiral biaryl amino acids, Nat. Commun., 2020 11, 946, 10.1038/s41467-020-14799-8.
8. Xue Li, Jun Xu, Shi-Jun Li, Ling-Bo Qu, Zhongjun Li, Yonggui Robin Chi, Donghui Wei* and Yu Lan*, Prediction of NHC-catalyzed chemoselectivefunctionalizations of carbonyl compounds:a general mechanistic map, Chem. Sci., 2020, 11, 7214-7225, 10.1039/d0sc01793k.
9. Xiao-Kang Guo, Lin-Bao Zhang, Donghui Wei*, Jun-Long Niu*, Mechanistic insights into cobalt(ii/iii)-catalyzed C-H oxidation: a combined theoretical and experimental study, Chem. Sci., 2015, 6, 7059-7071, 10.1039/c5sc01807b.
10. Xinghua Wang, Ya-Nan Wang, Zhipeng Pei, Shi-Jun Li, Donghui Wei*, and Yu Lan*, N-Heterocyclic Carbene/Brønsted Acid Cooperatively Catalyzed Conversions of α, β-Unsaturated Carbonyls: Hydrogen Bond Donor/Acceptor-Electrophile/Nucleophile Combination Models, ACS Catal., 2023, 13(1), 612−623, 10.1021/acscatal.2c05373.

*以上信息由高级会员个人更新和维护。