魏东辉

男， 郑州大学化学学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

2022.02—至今 郑州大学化学学院 教授
2017.01—2022.02 郑州大学化学学院 副教授
2013.01—2016.12 郑州大学化学与分子工程学院 讲师
2010.10—2012.11 美国肯塔基大学药学院 国家公派联合培养博士
2006.09—2012.12 郑州大学化学分子与工程学院 博士
2002.09—2006.07 郑州大学化学系 本科

研究领域和兴趣

理论与计算化学

主要业绩

曾先后获批国家自然科学基金项目3项、中国博士后科学基金面上资助和特别资助各1项、河南省自然科学基金优秀青年和杰出青年科学基金项目，入选河南省高等学校青年骨干教师、郑州大学青年拔尖人才、郑州大学优秀青年教师等培养计划。博士毕业论文被评为“河南省优秀博士学位论文”，曾获得“河南省优秀硕士和学士学位论文指导教师”称号。长期围绕有机催化反应（尤其是氮杂环卡宾催化反应）和生物酶催化及抑制反应的机理及其选择性、方向性轨道作用分析方法进行研究工作。近年来，以第一或通讯作者的身份在Nat. Catal.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Nature Commun.等杂志上正式发表论文180篇。

代表成果

1. Chao Lei, Wen Lu, Tingting Shen, Meng Huang, Yan-Xuan Wu, Donghui Wei*, Yan-Na Ma*, Xuenian Chen*, Palladium-catalysed asymmetric anti-Michael-type addition of α,β-unsaturated carboxylic acids with carboranes, Nat. Catal., 2026, 9,161–172, 10.1038/s41929-026-01480-4.
2. Wen-Hao Li, Man Zhang, Meng-Yao Niu, Yi-Yun Zhu, Xi-Ze Zhong, Lijie Liu, Yan-Na Ma*, Donghui Wei*, Xuenian Chen*, Evidence for Delocalization between o-Carborane and Triphenylethylene via an Alkynyl Bridge, J. Am. Chem. Soc., 2026, 148, 26736–26745, 10.1021/jacs.6c07624.
3. Xiaofei Shi, Jinshuai Song*, Donghui Wei*, An analysis method including orbital overlap directions for predicting π electron properties and reactivity vectors, Nat. Commun., 2025, 16, 3013, 10.1038/s41467-025-58281-9.
4. Yanyan Wang, Kuohong Chen, Fengrui Che, Sha Zhao, Pinpin Feng, Qiang Zhao, Donghui Wei*, Xingxing Wu*, Yonggui Robin Chi*, NHC-catalyzed covalent activation and control of P(V)-stereogenic phosphorus centers via phosphonyl azolium intermediates, Chem, 2025, 11, 102586, 10.1016/j.chempr.2025.102586.
5. Qianqian Shi, Zhipeng Pei, Jinshuai Song, Shi-Jun Li, Donghui Wei*, Michelle L. Coote*, Yu Lan*, Diradical Generation via Relayed Proton-Coupled Electron Transfer, J. Am. Chem. Soc., 2022, 144(7), 3137-3145, 10.1021/jacs.1c12360.
6. Junjian Wang, Donghui Wei*, Zheng Duan*, and Francois, Mathey Cleavage of the Inert C(sp2)-Ar σ Bond of Alkenes by a Spatial Constrained Interaction with Phosphinidene, J. Am. Chem. Soc., 2020, 142(50), 20973-20978, 10.1021/jacs.0c11195.
7. Simiao Zhang, Xiaoxue Wang, Li-Li Han, Jibin Li, Zheng Liang, Donghui Wei*, Ding Du*, Atroposelective Synthesis of Triaryl α-Pyranones with 1,2-Diaxes by N-Heterocyclic Carbene Organocatalysis, Angew. Chem. Int. Ed., 2022, 61(52), e202212005, 10.1002/anie.202212005.
8. Guanjie Wang, Qiao-Chu Zhang, Chenlong Wei, Ye Zhang, Linxue Zhang, Juhui Huang, Donghui Wei*, Zhenqian Fu*, and Wei Huang, Asymmetric Carbene-Catalyzed Oxidation of Functionalized Aldimines as 1,4-Dipoles, Angew. Chem. Int. Ed., 2021, 60(14), 7913-7919, 10.1002/anie.202017017.
9. Zhouli Hu, Chenlong Wei, Qianqian Shi, Xianfang Hong, Jinhua Liu, Xiangui Zhou, Jinna Han, Wei Cao, Ashis Kumar Gupta, Xiaoxiang Zhang, Donghui Wei*, Zhenqian Fu*, Wei Huang, Desymmetrization of N-Cbz glutarimides through N-heterocyclic carbene organocatalysis, Nat. Commun., 2022, 13, 4042, 10.1038/s41467-022-31760-z.
10. Guanjie Wang, Qianqian Shi, Wanyao Hu, Tao Chen, Yingying Guo, Zhouli Hu, Minghua Gong, Jingcheng Guo, Donghui Wei*, Zhenqian Fu* and Wei Huang*, Organocatalytic asymmetric N-sulfonyl amide C-N bond activation to access axially chiral biaryl amino acids, Nat. Commun., 2020 11, 946, 10.1038/s41467-020-14799-8.

*以上信息由高级会员个人更新和维护。