王春华

男， 佛山科学技术学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

2001.9-2005.6 中国药科大学，中药学，学士
2005.9-2008.6 中国药科大学，天然药物化学，硕士；
2009.9-2012.6 中国药科大学，天然药物化学，博士；
2012.7-2022.4 天津中医药大学，中药制药工程学院，助理研究员、副研究员；
2022.5-今 佛山科学技术学院，医学院，特聘教授

研究领域和兴趣

中药药效物质和中药成分合成生物学

主要业绩

主持完成国家自然科学基金项目1项、天津市科委重点项目1项；一般项目1项、教育部重点实验室项目1项、企业委托项目3项。目前在研广东省基础与应用基础研究基金粤佛联合基金1项（佛山科学技术学院项目负责人）。已完成对连花清瘟胶囊、参仙升脉口服液、生脉注射液等中药大品种进行了系统的科学研究工作、产生了良好的经济效益和社会效益；2022年获得中国产学研合作创新成果三等奖1项（1/10）；2021年获得天津市科学技术进步特等奖1项（5/12）；2017天津市科学技术进步三等奖1项（3/5）；2017年入选天津市131创新型人才第二层次人选。担任PLoS ONE、Journal of Chemistry学术编委，《中国药科大学学报》青年编委。

代表成果

1.Peng Shunhuan, Li Fangyi, Yu Kuo, Zhou Fengshu, Yu Heshui, Liu Hui, Guo Jialiang, Li Guoqiang, Wang Chunhua*, Yan Xiaohui*, Li Zheng*. Integrating transcriptome and chemical analyses to reveal the anti-Alzheimer’s disease components in Verbena officinalis Linn.. Frontiers in Plant Science, 2022, 13: 955075. doi: 10.3389/fpls.2022.955075.
2.Chen Peifang, Liu Shuang, Yin Zhao, Liang Pengjie, Wang Chunhua, Zhu Hanyue, Liu Yang, Ou Shiyi and Li Guoqiang*. Rutin alleviated acrolein-induced cytotoxicity in Caco-2 and GES-1 cells by forming a cyclic hemiacetal product. Frontiers in Nutrition, 2022, 9: 976400. doi: 10.3389/fnut.2022.976400.
3.Kuo Yu#, Ying Sun#, Lu Xue, Jingtao He, Fangyi Li, Maojing Yin, Zheng Li*, Xiaohui Yan, Jialiang Guo, Guoqiang Li, Chunhua Wang*. Compounds with NO Inhibitory Effect from the Rattan Stems of Sinomenium acutum, a Kind of Chinese Folk Medicine for Treating Rheumatoid Arthritis. Chemistry & Biodiversity, 2022, 19(6): e202200334.
4. Hongmei Zhang#, Fengshu Zhou#, Fangyi Li, Chunxia Zhao, Haixia Wang, Heshui Yu, Songtao Bie, Tongchuan Suo*, Zheng Li*, Guoqiang Li, Chunhua Wang*. Quality differentiation method of similar phytomedicines with high sugar content based on the sugar-marker: Taking Schisandrae Chinensis Fructus and Schisandrae Sphenantherae Fructus as an example. Arabian Journal of Chemistry, 2022, 15, 103727.
5. Kexin Kong#, Min Zhang#, Hongmei Zhang, Chengyu Zhang, Chunhua Wang*, Xiaohui Yan*. Structures and molecular mechanisms of action of the cholesterol C17 side-chain-degrading enzymes. Systems Microbiology and Biomanufacturing, 2022, https://doi.org/10.1007/s43393-022-00083-x.
6. Cheng Qian#, Peng Shuhuan#, Li Fangyi, Cui Pengdi, Zhao Chunxia, Yan Xiaohui, Suo Tongchuan, Wang, Chunhua*, He, Yongzhi, Li, Zheng*. Quality Distinguish of Red Ginseng from Different Origins by HPLC-ELSD/PDA Combined with HPSEC-MALLS-RID, Focus on the Sugar-Markers. Separations, 2021, 2021, 8, 198.
7. Qian Cheng#, Fangyi Li#, Xiaohui Yan, Jingtao He, Hongmei Zhang, Chunhua Wang*, Yongzhi He, Zheng Li*. Phytochemical and pharmacological studies on the genus Arcangelisia: A mini review. Arabian Journal of Chemistry, 2021, 14, 103346.
8. Jingtao He#, Fangyi Li#, Xiaohui Yan, Qian Cheng, Rongtao Xue, Heshui Yu, Chun-Hua Wang*, Zheng Li*. Phytochemical constituents and biological activities of plants from the genus Cissampelos. Chemistry and Biodiversity, 2021, DOI: 10.1002/CBDV.202100358.
9. Zhao Lan, Qiu Changfu, Zhao Lixin, Yin Guangwei, Li Fangyi*, Wang Chunhua*, Lizheng*. Base-promoted, CBr4-mediated tandam bromination/intramolecular Friedel-Crafts alkylation of N-aryl enamines: a facile access to 1H- and 3H- indoles. Organic and Biomolecular Chemistry, 2021, 19, 5377.
10. Li Zhenfa#, Zhao Lan#, Liang Liuyi, Zhao Lixin, Li Fangyi*, Wang Chunhua*, Li Zheng*. Additive-free copper(I)-mediated synthesis of 5- or 6‑brominated 2‑aryl‑1H‑indole-3-carboxylates from α, α-dibromo β‑iminoesters. The Journal of Organic Chemistry, 2021, 86: 1964-1971.

*以上信息由高级会员个人更新和维护。