杨婷

女， 东北大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

2004-2008 东北大学 应用化学 本科
2008-2014 东北大学 分析化学 博士
2012-2013 美国德州大学 CSC联合培养博士
2014-2015 东北大学 讲师
2016-2018 东北大学 副教授
2019至今 东北大学 教授

研究领域和兴趣

分离分析、液体活检、工程化噬菌体

主要业绩

聚焦生命健康前沿领域，着眼于复杂基体样品中有效信息的捕获与提取关键科学问题，开展了包括癌症在内的重大疾病早期诊断及病原菌鉴定等工作。近年来，针对复杂体系中精准测量的瓶颈问题，发展了生物颗粒型靶标的高效分离、灵敏检测与精准分型方法，包括：1）发展高效捕获与抗污协同的分离策略，显著提升低丰度靶标高纯度富集能力；2）发展基于传质增强与局部浓度调控的检测方法，显著提高大尺寸靶标分析灵敏度；3）发展多维信号输出与单颗粒解析方法，显著提升异质靶标分型与鉴定准确度。以通讯或一作发表SCI论文61篇（独立通讯20篇），含Nat Commun、Angew. Chem.、Anal Chem、ACS Nano等，主持面上项目4项，青B项目1项，获辽宁省优青、辽宁省“兴辽英才”青年拔尖计划资助。

代表成果

1. Hui-Da Li, Yuan-Qiang Chen, Yan Li, Xing Wei, Si-Yi Wang, Ying Cao, Rui Wang, Cong Wang, Jing-Yue Li, Jian-Yi Li*, Hong-Ming Ding*, Ting Yang*, Jian-Hua Wang and Chuanbin Mao*. Harnessing virus flexibility to selectively capture and profile rare circulating target cells for precise cancer subtyping. Nature Communications. 2024, 15, 5849.
2. Lilin Yin, Xianyao Han, Fulin Guo, Yuning Zou, Qingpeng Xie*, Jianhua Wang, Chaoyong Yang* and Ting Yang*. An All-in-one Nanohole Array for Size-Exclusive Trapping and High-Throughput Digital Counting of Single Extracellular Vesicles for Non-invasive Cancer Screening. Angewandte Chemie International Edition. 2025, 64(29), e202506744.
3. Na Wu, Xin-Yu Zhang, Jie Xia, Xin Li, Ting Yang*, and Jian-Hua Wang. Ratiometric 3D DNA Machine Combined with Machine Learning Algorithm for Ultrasensitive and High-Precision Screening of Early Urinary Diseases, ACS Nano 2021, 15(12), 19522–19534
4. Ying Cao, Yue Xu, Tingli Luo, Jianyi Li, Zhen Wang, Cheng Du*, Jianyu Yang, Jianhua Wang, Ting Yang*. Nanotentacle-Armed Flexible Affinity Interface Enables Streamlined Capture, Labeling, and Release of Circulating Tumor Cells. ACS Nano 2025, 19(33), 30115−30124.
5. Ying Cao, Na Wu, Hui-Da Li, Jing-Wen Xue, Rui Wang, Ting Yang*, Jian-Hua Wang. Efficient Pathogen Capture and Sensing Promoted by Dynamic Deformable Nanointerfaces. Small. 2022, 18 (51), 2203962
6. Siyi Wang, Yushuang Guo, Xin Wang, Xuan Zhang*, Ting Yang*, Jian-Hua Wang. Multiplex Sensing of Biomarkers on the Cancer Cell Surface by an Epithelial-Mesenchymal Transition (EMT) Sensing Panel Enables Precise Differentiating of Cancer Cells at Various EMT Stages. Analytical Chemistry 2024, 96, 32, 13270-13277
7. Huida Li, Fengting Jia, Xin Wang, Ting Yang*, Jian-Hua Wang. Efficient and Discriminative Isolation of Circulating Cancer Stem Cells and Non-Stem-like Circulating Tumor Cells Using a Click-Handle-Loaded M13 Phage-Based Surface. Analytical Chemistry 2025, 97, 14, 8080–8087.
8. Xin Wang, Huida Li, Jianyu Yang, Chengxin Wu, Mingli Chen, Jianhua Wang, and Ting Yang*. Chemical Nose Strategy with Metabolic Labeling and “Antibiotic-Responsive Spectrum” Enables Accurate and Rapid Pathogen Identification. Analytical Chemistry 2024, 96, 427−436
9. Meijun Liu, Xing Wei, Chengxin Wu, Jinhui Liu, Yujia Wei, Xuesheng Wang, Ming-Li Chen, Ting Yang,* and Jian-Hua Wang*. Single Cell Phenotypic Analysis for Cancer Stem Cell Identification by Dual-Isotope ICP-QMS. Analytical Chemistry 2023, 95, 14447−14454
10. Siyi Wang, Jiasen Cui, Qian Fan, Jiaxing Gan, Chunran Liu, Yuanhe Wang*, Ting Yang*, Jianhua Wang, and Chaoyong Yang. Reversible and Highly Ordered Biointerfaces for Efficient Capture and Nondestructive Release of Circulating Tumor Cells. Analytical Chemistry 2022, 94, 26, 9450–9458

*以上信息由高级会员个人更新和维护。