闵俊哲

男， 延边大学 药学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

1995.9-1999.6 延边大学 药学院 药学 学士
1999.7-2000.5 延边大学草仙药业 车间主任
2000.6-2002.3 日本 国际语言学校
2002.4-2004.3 日本 静冈县立大学 药物分析 硕士
2004.4-2007.3 日本 静冈县立大学 药物分析 博士
2007.4-2012.12 日本 静冈县里大学 药学部 教师
2013.01-至今 延边大学 药学院 教师

研究领域和兴趣

手性代谢组学，糖组学，慢病预警和诊断试剂盒

主要业绩

现任延边大学药学院，教授、博士生导师，药学一级博士点药物分析二级学科带头人，“吉林省百名高层次创新创业人才”，“图们江学者”， 全国药物分析技术分会第二届常务委员，教育部学位中心博士学位论文评审专家，全国专业学位水平评估函审专家。日本静冈县立大学客座教授。Frontiers in chemistry杂志Analytical Chemistry副主编。2020年赴浙江大学药学院从事中央组织部 “西部之光访问学者”一年（师从曾苏教授）。2021年作为执行主席在延吉成功主办“全国药物分析学科战略发展研讨会”。
现主要致力于“手性代谢组学高灵敏度质谱手性探针试剂的开发及应用”；“糖蛋白糖链的在线快速、简便、高灵敏度定量分析方法的建立”；“中药/朝药复方制剂物质基础、作用机理及代谢通路研究”；“糖尿病、癌症等慢性疾病早期预警及诊断用非侵袭性试剂盒的开发”。日本任教期间主持完成日本文部科学省项目3项（相当于中国面上项目2项，重点项目1项），其他财团、日本科学技术振兴机构成果推广项目等共3项。现主持和完成国家自然科学基金项目4项（地区3项，面上1项），教育部博士点专项基金1项, 吉林省科技厅重点和教育厅项目共3项。发表SCI论文120余篇，已授权日本专利3项，国内专利2项，申请公开3项。已培养“青年图们江学者”等优秀博士毕业生7名，硕士生32名。先后获得日本药学会东海支部激励奖，日本色谱学会激励奖。延边朝鲜族自治州科学技术发明奖，吉林省科学技术自然科学三等奖，第七届全国药物分析大会暨第三届药物分析国际论坛“岛津优秀论文二等奖”。

代表成果

1）Shengyu Cheng, Songze Wang, Mingshan Zheng, Yueying Jin , Jing Li , Minghui Zhang , Xi-Ling Li , Jun Zhe Min*, Simultaneous analysis of natural and artificial sweeteners in sugar-free drinks and urine samples by column-switching UHPLC-charged aerosol detection method, Journal of Chromatography A, 2024, 464533.
2）Xi-Ling Li, Yuxuan Li, Shuyun Xiao, Qingsong Li, Chengqiang Han, Danyang Liu, Tengfei Cui, Xiyang Rao, Kenichiro Todoroki, Guang Yang*, Jun Zhe Min*, Stable isotope labeling differential glycans discovery in the serum of acute myocardial infarction by ultrahigh-performance liquid chromatography-quadrupole-Orbitrap high resolution mass spectrometry, Analytica Chimica Acta, 2023, 1264, 341269.
3) Jing Li, Xin Zhou, Morotomi Takashi, Kenichiro Todoroki, Toshimasa Toyo'oka, Qing Shi*, Toufeng Jin*, Jun Zhe Min*, Development of a novel method for analysing N-acetyl-DL-leucine enantiomers in human fingernail by UPLC-ESI-MS/MS and the evaluation in diabetes mellitus, Clinica Chimica Acta, 2023, 545, 117367.
4）Yu Han, Haihong Hu, Lushan Yu, Su Zeng, Jun Zhe Min*, Sheng Cai*, A duplex-specific nuclease (DSN) and catalytic hairpin assembly (CHA)-mediated dual amplification method for miR-146b detection, Analyst, 2023, 148, 556-561.
5）Lei Di, Shengyu Cheng, Yan Zhu, Yueying Jin, Chao Qi, Lingli Zhang, Minghui Zhang, Xin Wang, Yu Han*, Xi-Ling Li*, Jun Zhe Min*, Development of a diphenyl sulfide structure derivatization reagent for amino acid enantiomers analysis: Application of dynamic monitoring in human urine after drinking wine, Journal of Chromatography A, 2023, 1688, 463698.
6) Chao Qi, Yueying Jin, Shengyu Cheng, Lei Di, Xin Wang, Minghui Zhang, Lingli Zhang, Xi-Ling Li, Yu Han*, Qingkun Ma*, Jun Zhe Min*, A novel UHPLC-MS/MS method for the determination of four α-dicarbonyl compounds in wine and dynamic monitoring in human urine after drinking, Food Research International (Food Res. Int.,) 2023,163, 112170.
7）Yueying Jin, Shengyu Cheng, Ruobai Liu, Chenglong Yu , Lingli Zhang , Xi-Ling Li , Guanghai Yan*, Mingyu Zheng*, Jun Zhe Min*, Comprehensive characterization of the chemical composition of Lurong dabu decoction and its absorbed prototypes and metabolites in rat plasma using UHPLC–Q Exactive Orbitrap–HRMS, Food Research International, 2022, 161, 111852.
8）Xi-Ling Li, Chengqiang Han, Miao Luo, Shuyun Xiao, Jing Li, Chenglong Yu, Shengyu Cheng, Yueying Jin, Yu Han, Kenichiro Todoroki, Qing Shi∗, Jun Zhe Min∗, Relative quantitation of glycans in cetuximab using ultra-high-performance liquid chromatography-high-resolution mass spectrometry by Pronase E digestion, Journal of Chromatography A, 1677 (2022) 463302.
9）Shengyu Cheng, Xianglin Xu, Xinxin Kong, Yudi Jiang, Luxuan Mo, Mingxia Li, Yueying Jin, Yu Han, Xi-Ling Li, Toufeng Jin*, Jun Zhe Min*, Monitoring of salicylic acid content in human saliva and its relationship with plasma concentrations, Journal of Pharmaceutical and Biomedical Analysis, 2022, 219, 114961.
10）Xi-Ling Li, Wenhao Li, Chao Qi, Li-Li Zhao, Wenlong Jin*, Jun Zhe Min*, Determination of N-acetyl-DL-leucine in the saliva of healthy volunteers and diabetic patients using ultra-performance liquid chromatography with fluorescence detection, Clinica Chimica Acta, 526 (2022) 66-73.
11）Xi-Ling Li, Yu Han, Yuan Huang, Xiaoqi Sun, Shuyun Xiao, Jun Zhe Min*, Highly sensitive novel fluorescent chiral probe possessing(S)-2-methylproline structures for the determination of chiral aminocompounds by ultra-performance liquid chromatography withfluorescence: An application in the saliva of healthy volunteer, Journal of Chromatography A, 2022, 1661, 462672.
12）Yu Han#, Xi-Ling Li#, Minghui Zhang#, Jing Wang, Su Zeng*, Jun Zhe Min*, Potential use of a dried saliva spot (DSS) in therapeutic drug monitoring and disease diagnosis, Journal of Pharmaceutical Analysis, 2022, 12, 815-823.
13）Qingkun Ma, Xi-Ling Li, Chao Qi, Minghui Zhang, Yan Zheng, Qing Shi, Yueying Jin, Lei Di, Jun Nan, Jun Zhe Min*, Simultaneous determination of chiral thiol compounds and monitoring of dynamic changes in human urine after drinking Chinese Korean ethnic rice wine, Journal of Agricultural and Food Chemistry (J. Agric. Food Chem.,) 2021, 69, 5416−5427.
14）Qingkun Ma, Xiaoxi Man, Chun-Yan Xu, Jian Huo, Chao Qi, Qing Shi, Jun Nan*, Jun Zhe Min*, Simultaneous determination of chiral homocysteine, cysteine and glutathione, in serum from humans at normal and stress states using ultrahigh-performance liquid chromatography coupled to quadrupole-Orbitrap high resolution mass spectrometry, Journal of Chromatography A (J. Chromatogr. A), 2021, 1642, 462028.
15）Qingkun Ma, Chao Qi, Xi-Ling Li, Qing Shi, Chun-Yan Xu, Toufeng Jin*, Jun Zhe Min*, Simultaneous Determination of DL-Cysteine, DL-Homocysteine, and Glutathione in Saliva and Urine by UHPLC-Q-Orbitrap HRMS: Application to Studies of Oxidative Stress, J. Pharm. Biomed. Anal., 2021, 196, 113939.

*以上信息由高级会员个人更新和维护。