赵丽娜

女， 中国科学院高能物理研究所， 教授/研究员/教授级高工或同等级别

学习/工作经历

1996.9-2000.7 北京理工大学 应用物理 学士
2000.9-2005.3 北京理工大学 物理学院 博士
2005.4-2007.3 北京大学 物理学院 博士后
2006.5-2008.10 新加坡南洋理工大学 Atomistix科学计算中心 算法科学家
2008.12-至今 中国科学院高能物理研究所 多学科研究中心 副研究员、研究员

研究领域和兴趣

物理化学、计算化学、纳米化学

主要业绩

现为高能所多学科中心学术委员会委员、纳米生物效应研究组组长。中国生物物理学会纳米生物分会委员、纳米酶分会委员。瑞士国家自然基金评审人。曾获ACS Nano青年科学家奖。重点开展纳米生物效应分子机制的多尺度模拟计算研究、相关纳米新结构预测的同步辐射科学大数据深度学习挖掘研究。以通讯/第一作者在Nature Nanotechnology, Science Advance, Nano Letters, Nano Today, Small等权威期刊发表SCI文章50余篇。撰写纳米生物效应相关合著著作一部（Wiley-VCH出版社）。自主知识产权的深度学习算法成果获得计算机软件著作权登记证书（2023SR0370192, 2018SR927423）。主持国家自然科学基金四项、国家重点专项课题两项、国家重大科研仪器项目课题一项。

代表成果

1. Minghui Sun#, Zheng Dong#, Liyuan Wu, Haodong Yao, Wenchao Niu, Deting Xu, Ping Chen, Himadri S Gupta, Yi Zhang*, Yuhui Dong, Chunying Chen, Lina Zhao*, Fast extraction of three-dimensional nanofiber orientation from WAXD patterns using machine learning, IUCrJ 10, 3 (2023). DOI: 10.1107/S205225252300204X
2. Deting Xu, Wenyan Yin, Jie Zhou, Liyuan Wu, Haodong Yao, Minghui Sun, Ping Chen, Xiangwen Deng and Lina Zhao*, Rational design of MoS2 supported Cu single atom catalysts by machine learning potential for enhanced peroxidase-like activity, Nanoscale 15, 6686-6695 (2023). DOI: 10.1039/D2NR07270J
3. Jie Zhou#, Deting Xu#, Gan Tian#, Qian He, Xiao Zhang, Jing Liao, Linqiang Mei, Lei Chen, Lizeng Gao, Lina Zhao*, Guoping Yang*, Wenyan Yin*, Guangjun Nie and Yuliang Zhao, Coordination-Driven Self-Assembly Strategy-Activated Cu Single-Atom Nanozymes for Catalytic Tumor-Specific Therapy‍, Journal of the American Chemical Society 145 (7), 4279-4293 (2023). DOI: 10.1021/jacs.2c13597
4. Ying Shi#, Kefeng Pu#, Haodong Yao#, Yingting Chen, Xuewen Zheng, Lina Zhao*, Xiaochuan Ma*, and Cuicui Ge*, Gold Nanorods Inhibit Tumor Metastasis by Regulating MMP-9 Activity: Implications for Radiotherapy, ACS Appl. Mater. Interfaces (2023). DOI: 10.1021/acsami.2c20944
5. Deting Xu, Liyuan Wu, Haodong Yao, and Lina Zhao*,Catalase-Like Nanozymes: Classification, Catalytic Mechanisms, and Their Applications. Small 18, 2203400 (2022). D‍OI:10.1002/smll.202203400
6. Wenchao Niu, Zhongying Du, Chunyu Zhang, Deting Xu, Jiaojiao Li, Minghui Sun, Liyuan Wu, Haodong Yao, Lina Zhao*, and Xueyun Gao*, Broken electron transfer pathway in enzyme: Gold clusters inhibiting TrxR1/Trx via cell studies and theory simulations. Chinese Chemical Letters 33, 3488-3491 (2022). DOI:10.1016/j.cclet.2022.04.004
7. Jiani Xie#, Maoru Zhao#, Chengyan Wang, Shuang Zhu, Wenchao Niu, Yuan Yong*, Lina Zhao*, Zhanjun Gu* "External use of Nano-graphdiyne hydrogel for skin radioprotection via both physically shielding of Low-energy X-ray and chemically scavenging of Broad-spectrum free radicals" Chem. Eng. J. 430, 132866 (2022). DOI:10.1016/j.cej.2021.132866
8. Mingjing Cao#, Rong Cai#, Lina Zhao#, Mengyu Guo#, Liming Wang, Yucai Wang, Lili Zhang, Xiaofeng Wang, Haodong Yao, Chunyu Xie, Yalin Cong, Yong Guan, Xiayu Tao, Yaling Wang, Shaoxin Xu, Ying Liu, Yuliang Zhao & Chunying Chen*, Molybdenum derived from nanomaterials incorporates into molybdenum enzymes and affects their activities in vivo, Nature Nanotechnology 16, 708–716 (2021). DOI:10.1038/s41565-021-00856-w
9. Huanli Yao#, Haodong Yao#, Huan Huang, Lele Zhang, Rongli Cui, Xihong Guo, Hu Cheng, Yanchun Li, Xiaodong Li*, Xingfa Gao, Lina Zhao*, Baoyun Sun*, Carbon phase adjustment by multi-configuration ligand in endohedral metallofullerene derivatives Gd@C82(morpholine)7 under high pressure, Nano Today 37, 101079 (2021). DOI:10.1016/j.nantod.2021.101079
10. Gao, Liang, Ya Zhang, Lina Zhao*, Wenchao Niu, Yuhua Tang, Fuping Gao, Pengju Cai, Qing Yuan, Xiayan Wang, Huaidong Jiang and Xueyun Gao*. "An artificial metalloenzyme for catalytic cancer-specific DNA cleavage and operando imaging." Science advances 6(29), eabb1421 (2020). DOI:10.1126/sciadv.abb1421

*以上信息由高级会员个人更新和维护。