张卉

女， 南京师范大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

1998.9-2002.6 河南师范大学 化学教育 本科
2002.9-2005.6 河南师范大学 分析化学 硕士
2005.9-2008.8 南京大学 分析化学 博士
2008.12-2011.5 南京师范大学 化学与材料科学学院 讲师
2011.5-2017.5 南京师范大学 化学与材料科学学院 副教授
2015.4-2016.5 美国佛罗里达大学访问学者
2017.5-至今 南京师范大学 化学与材料科学学院 教授
2019.8-2020.8 美国南卡罗来纳大学 访问学者

研究领域和兴趣

纳米生物电分析化学

主要业绩

申请人近年来一直从事纳米生物电分析方面的工作。主要研究内容为生物相容性纳米材料的制备及在生物传感器上的应用、DNA甲基化、肿瘤标志物的电化学及电致化学发光检测。已在纳米材料的合成、电催化、电致化学发光和生物传感方面积累了较为扎实的理论基础和丰富的实践经验，形成了自己的工作特色和优势。到目前为止，已在Anal. Chem.，Chem. Commun.，Biosens. Bioelectron.，J. Phys. Chem. B/C，中国科学B辑等国内外杂志上发表论文80余篇。

代表成果

1. Yongqi Yu, Qunqun Guo, Wenli Jiang, Hui Zhang,* and Chenxin Cai. Dual-aptamer-assisted AND logic gate for cyclic enzymatic signal amplification electrochemical detection of tumor-derived small extracellular vesicles. Anal. Chem. 2021, 93(32), 11298-11304.
2. Qunqun Guo, Yongqi Yu, Hui Zhang,* Chenxin Cai, and Qingming Shen. Electrochemical sensing of exosomal microRNA based on hybridization chain reaction signal amplification with reduced false-positive signals. Anal. Chem. 2020, 92(7), 5302-5310.
3. Hui Zhang*, Bin Qiao, Qunqun Guo, Juqian Jiang, Chenxin Cai, Jian Shen. A facile and label-free electrochemical aptasensor for tumour-derived extracellular vesicle detection based on the target-induced proximity hybridization of split aptamers. Analyst. 2020, 145(10), 3557-3563.
4. Juqian Jiang, Yongqi Yu, Hui Zhang*, Chenxin Cai. Electrochemical aptasensor for exosomal proteins profiling based on DNA nanotetrahedron coupled with enzymatic signal amplification. Anal. Chim. Acta. 2020, 1130, 1-9.
5. Hui Zhang*, Mengxing Fan, Juqian Jiang, Qingming Shen*, Chenxin Cai, Jian Shen*. Sensitive electrochemical biosensor for MicroRNAs based on duplex-specific nuclease-assisted target recycling followed with gold nanoparticles and enzymatic signal amplification. Anal. Chim. Acta, 2019, 1064, 33-39.
6. Bin Qiao, Qunqun Guo, Juqian Jiang, Yunlong Qi, Hui Zhang*, Bangshun He*, Chenxin Cai, Jian Shen*. An electrochemiluminescent aptasensor for amplified detection of exosomes from breast tumor cells (MCF-7 cells) based on G-quadruplex/hemin DNAzymes. Analyst. 2019, 144(11), 3668-3675.
7. Bin Qiao, Hongfei Chen, Hui Zhang*, Chenxin Cai. Analysis and detection of tumor exosomes. Progress in Chemistry, 2019, 31(6), 847-857.
8. Huilei Dong, Hongfei Chen, Juqian Jiang, Hui Zhang,* CHenxin Cai, and Qingming Shen*. Highly sensitive electrochemical detection of tumor exosomes based on aptamer recognition-induced multi-DNA release and cyclic enzymatic amplification. Anal. Chem. 2018, 90(7), 4507−4513.
9. Zhihui Guo, Bin Qiao, Qunqun Guo, Hui Zhang*, Chenxin Cai, Jiu-Ju Feng*. Dual-signal ratiometric electrochemiluminescence assay for detecting the activity of human methyltransferase. Analyst. 2018, 143(14), 3353-3359.
10. Yin Yang, Guoqing Yang, Hongfei Chen, Hui Zhang*, Jiu-Ju Feng*, Chenxin Cai. Electrochemical signal-amplified detection of 5-methylcytosine and 5-hydroxymethylcytosine in DNA using glucose modification coupled with restriction endonucleases. Analyst. 2018, 143(9), 2051-2056.

*以上信息由高级会员个人更新和维护。