邹千里

男， 安徽医科大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

2002.09－2006.07，北京师范大学，化学学院，理学学士
2008.09－2013.07，中国科学院，理化技术研究所，理学博士
2013.08－2016.07，中国科学院，过程工程研究所，助理研究员
2016.07－2020.08，中国科学院，过程工程研究所，副研究员
2020.08－至今，安徽医科大学，药学院，教授，博士生导师

研究领域和兴趣

生物分子组装；药物递送系统；抗肿瘤治疗

主要业绩

安徽省“皖江学者”特聘教授，获安徽省自然科学基金杰青项目资助，主要从事自组装药物制剂的研究。以生命体系中色素蛋白质等超分子结构为指导，揭示蛋白质、肽、卟啉等生物分子的自组装过程规律和弱相互作用机制，建立基于生物分子自组装的药物微纳米制剂可控制备技术，研究自组装药物制剂在智能药物递送、光热治疗、光动力治疗、抗菌、抗肿瘤、炎症免疫性疾病等领域的应用及产业化。在Adv. Mater.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、J. Controlled Release、和Small等学术期刊发表论文60余篇。SCI他引5000余次，单篇最高他引600余次。获授权中国发明专利10项。入选ChemBioChem期刊“ChemBioTalents 2022”，并多次在国内外会议做学术报告。完成和正在主持国家自然科学基金3项。

代表成果

1. Zou, Q. L.*; Bao, J. W.; Yan, X. H.* Functional Nanomaterials Based on Self-Assembly of Endogenic NIR-Absorbing Pigments for Diagnostic and Therapeutic Applications. Small Methods 2022, 6, 2101359, https://doi.org/10.1002/smtd.202101359.
2. Geng, R.; Chang, R.; Zou, Q. L.*; Shen, G. Z.; Jiao, T. F.*; Yan, X. H.* Biomimetic Nanozymes Based on Coassembly of Amino Acid and Hemin for Catalytic Oxidation and Sensing of Biomolecules. Small 2021, 17, 2008114, https://doi.org/10.1002/smll.202008114.
3. Liu, Y. M.; Naumenko, E.; Akhatova, F.; Zou, Q. L.*; Fakhrullin, R.*; Yan, X. H.* Self-Assembled Peptide Nanoparticles for Enhanced Dark-Field Hyperspectral Imaging at the Cellular and Invertebrate Level. Chem. Eng. J. 2021, 424, 130348, https://doi.org/10.1016/j.cej.2021.130348.
4. Zou, Q. L.#; Chang, R.#; Xing, R. R.; Yuan, C. Q.; Yan, X. H.* Injectable Self-Assembled Bola-Dipeptide Hydrogels for Sustained Photodynamic Prodrug Delivery and Enhanced Tumor Therapy. J. Controlled Release 2020, 319, 344-351, https://doi.org/10.1016/j.jconrel.2020.01.002.
5. Sun, H. F.#; Chang, R.#; Zou, Q. L.*; Xing, R. R.; Qi, W.*; Yan, X. H.* Supramolecular Protein Nanodrugs with Coordination- and Heating-Enhanced Photothermal Effects for Antitumor Therapy. Small 2019, 15, 1905326, https://doi.org/10.1002/smll.201905326.
6. Liu, Y. M.; Shen, G. Z.; Zhao, L. Y.; Zou, Q. L.*; Jiao, T. F.*; Yan, X. H.* Robust Photothermal Nanodrugs Based on Covalent Assembly of Nonpigmented Biomolecules for Antitumor Therapy. ACS Appl. Mater. Interfaces 2019, 11, 41898-41905, https://doi.org/10.1021/acsami.9b13966.
7. Zou, Q. L.#; Abbas, M.#; Zhao, L.; Li, S.; Shen, G.; Yan, X. H.* Biological Photothermal Nanodots Based on Self-Assembly of Peptide-Porphyrin Conjugates for Antitumor Therapy. J. Am. Chem. Soc. 2017, 139, 1921-1927, https://doi.org/10.1021/jacs.6b11382.
8. Xing, R. R.#; Liu, K.#; Jiao, T. F.*; Zhang, N.; Ma, K.; Zhang, R. Y.; Zou, Q. L.*; Ma, G. H.; Yan, X. H.* An Injectable Self-Assembling Collagen-Gold Hybrid Hydrogel for Combinatorial Antitumor Photothermal/Photodynamic Therapy. Adv. Mater. 2016, 28, 3669-3676, https://doi.org/10.1002/adma.201600284.
9. Zou, Q. L.#; Zhao, H.#; Zhao, Y.*; Fang, Y.; Chen, D.; Ren, J.; Wang, X.; Wang, Y.; Gu, Y.*; Wu, F.* Effective Two-Photon Excited Photodynamic Therapy of Xenograft Tumors Sensitized by Water-Soluble Bis(arylidene)cycloalkanone Photosensitizers. J. Med. Chem. 2015, 58, 7949-7958, https://doi.org/10.1021/acs.jmedchem.5b00731.
10. Zou, Q. L.; Zhang, L.; Yan, X. H.*; Wang, A. H.; Ma, G. H.; Li, J. B.; Mohwald, H.; Mann, S.* Multifunctional Porous Microspheres Based on Peptide-Porphyrin Hierarchical Co-Assembly. Angew. Chem. Int. Ed. 2014, 53, 2366-2370, http://dx.doi.org/10.1002/anie.201308792.

*以上信息由高级会员个人更新和维护。