肖春生

男， 中国科学院长春应用化学研究所， 教授/研究员/教授级高工或同等级别

学习/工作经历

2002-2006，中国科学技术大学，高分子科学与工程专业，本科
2006-2012，中国科学院长春应用化学研究所，高分子化学与物理专业，博士
2012-2014，中国科学院长春应用化学研究所，中科院生态环境高分子材料重点实验室，助理研究员
2014-2020，中国科学院长春应用化学研究所，中科院生态环境高分子材料重点实验室，副研究员
2020-2022，中国科学院长春应用化学研究所，中科院生态环境高分子材料重点实验室，项目研究员
2022-至今，中国科学院长春应用化学研究所，中科院生态环境高分子材料重点实验室，研究员

研究领域和兴趣

生物医用高分子材料

主要业绩

主要从事生物医用高分子材料的设计、制备及其在生物医学领域的应用。研究组围绕疾病的精准诊断和治疗，开展高分子纳米药物、抗菌高分子材料、仿生矿化水凝胶和生物成像分析等相关研究。迄今在CCS Chem., Adv. Mater., Adv. Funct. Mater., ACS Nano等国际主流期刊上发表一作/通讯作者论文120余篇。论文引用1.1万余次，H因子62。申请国家发明专利39项，其中已获授权25项。作为项目负责人，主持国家自然科学基金项目5项，主持吉林省优秀青年人才基金项目和重点研发项目各1项。2025年获吉林省科技进步奖一等奖。担任《Chinese Journal of Polymer Science》、《高分子学报》和《高分子通报》三刊联合青年编委。

代表成果

1. Zhao M., Zhang X.*, Xiao C.*, Chen X., Biomimetic Mineralized Hydrogels for Bone Regeneration. Advanced Materials 2026, 38 (9), e20380.
2. Bao Y., Gao Z., Yan Y., Duan Y., Zhao Y., Wang H.*, Xiao C.*, Chen X., Covalent Organic Framework-Based Ultrasensitive Bioorthogonal Raman Probes for In Vivo Detection of Bone Crack. Advanced Functional Materials 2026, 36 (22), e22613.
3. Guo, Z., Huang, T., Yin, R., Tian, Y., Wan, P., Yi, X., Li, G., Zhang, P.*, Xiao, C.*, Chen, X.*, Cationic Spherical Polypeptides with Immunogenic Cell Death Inducing Activity for Oncolytic Immunotherapy. CCS Chemistry 2025, 7, 180-193.
4. Zhang P., Yao Q., Zhang X., Yi X., Xiao C.*, Chen X., Fenton Reaction-Mediated Endolysosomal Disruption for Efficient Cytosolic Protein Delivery. ACS Nano 2025, 19 (39), 34527-34539.
5. He, X., Yu, J., Yin, R., Zhang, P.*, Xiao, C.*, Chen, X.*, A Nanoscale Trans-Platinum(II)-Based Supramolecular Coordination Self-Assembly with a Distinct Anticancer Mechanism. Advanced Materials 2024, 36 (19), 2312488.
6. Zhang, X., Zhang, Y., Lv, X., Zhang, P.*; Xiao, C.*; Chen, X.*, DNA-Free Guanosine-Based Polymer Nanoreactors with Multienzyme Activities for Ferroptosis–Apoptosis Combined Antitumor Therapy. ACS Nano 2024, 18 (49), 33531-33544.
7. Liu, J., Zhang, X., Xiao, C.*, Chen, X.*, A Drug-Mineralized Hydrogel Orchestrated by Spontaneous Dynamic Mineralization. Advanced Functional Materials 2024, 34 (12), 2311844.
8. Ding, X., Li, G., Zhang, P., Jin, E., Xiao, C.*, Chen, X., Injectable Self-Healing Hydrogel Wound Dressing with Cysteine-Specific On-Demand Dissolution Property Based on Tandem Dynamic Covalent Bonds. Advanced Functional Materials 2021, 31 (19), 2011230.
9. Zhang, P., Zhang, Y., Ding, X., Shen, W., Li, M., Wagner, E., Xiao, C.*, Chen, X.*, A Multistage Cooperative Nanoplatform Enables Intracellular Co-Delivery of Proteins and Chemotherapeutics for Cancer Therapy. Advanced Materials 2020, 32 (46), 2000013.
10. Shen, W., Zhang, Y., Wan, P., An, L., Zhang, P., Xiao, C.*, Chen, X.*, Antineoplastic Drug-Free Anticancer Strategy Enabled by Host-Defense-Peptides-Mimicking Synthetic Polypeptides. Advanced Materials 2020, 32 (36), 2001108.

*以上信息由高级会员个人更新和维护。