乐学义

男， 华南农业大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

1978.09-1982.07, 湖北师范大学(原黄石师范学院）化学系,本科生
1982.08-1985.08, 湖北省应城市教师进修学校,教师
1985.09-1988.06, 华中师范大学化学系,硕士研究生
1988.06-1993.08, 湖北工程学院（原孝感师范专科学校）化学系,讲师
1993.09-1996.06, 中山大学化学化工学院,博士研究生
1997.12-2001.12, 华南农业大学理学院，副教授、硕士生导师(1999.06-)，期间担任应用化学系副主任(2001.03-2001.04) 、理学院副院长兼任应用化学系主任（2001.05- 2006.12）
2001.12-2014.12，华南农业大学理学院,教授(破格) 、博士生导师(2005/06-)，期间担任理学院院长（2007/01-2014/12）
2015.01-现在, 华南农业大学材料与能源学院应用化学系,教授,博(硕)士生导师

研究领域和兴趣

生物无机化学

主要业绩

长期从事生物无机化学、药物化学、食品科学等交叉学科研究,先后承担省部级以上科研项目20余项,已公开发表学术论文180多篇,其中90余篇被SCI收录,获得国家发明专利2项,作为主要参加人获广东省自然科学一等奖1项,合作出版编著1本。

代表成果

1. Dai-Hong Cai, Chun-Lian Zhang, Qi-Yan Liu, Liang He, Yun-Jun Liu, Ya-Hong Xiong, Xue-Yi Le*. Synthesis, DNA binding, antibacterial and anticancer properties of two novel water-soluble copper(II)
complexes containing gluconate. European Journal of Medicinal Chemistry,213( 2021), doi.org/ 10.1016/ j.ejmech. 2021.113182
2. Yong-Yu Qi, Qian Gan , Ya-Xian Liu, Ya-Hong Xiong, Zong-Wan Mao, Xue-Yi Le*. Two new Cu(II) dipeptide complexes based on 5-methyl-2-(2’-pyridyl)benzimidazole as potential antimicrobial and anticancer drugs:Special exploration of their possible anticancer mechanism. European Journal of Medicinal Chemistry, 154(2018), DOI: 10.1016/j.ejmech.2018.05.023;
3．Chun-Lian Zhang, Ya-Xian Liu, Xue-Mei Zhang, Shi Chen, Fang Shen, Ya-Hong Xiong, Wei Liu,, Zong-Wan Mao, Xue-Yi Le*. Synthesis, characterization, DNA/HSA interactions and in vitro cytotoxic activities of two novel water-soluble copper(II) complexes with 1,3,5-triazine derivative ligand and amino acids. Materials Science & Engineering C, 91(2018), DOI: 10.1016/j.msec.2018.05.065;
4.Yujia Liu, Yanxue Cai, Danyang Ying, Yinlian Fu, Yahong Xiong, Xueyi Le*. Ovalbumin as a carrier to significantly enhance the aqueous solubility and photostability of curcumin: Interaction and binding mechanism study. International Journal of Biological Macromolecules, 116(2018), DOI: 10.1016/j.ijbiomac.2018.05.089;
5. Xia-Bing Fu, Dan-Dan Liu, Yuan Lin, Wei Hu, Zong-Wan Mao and Xue-Yi Le*. Water-soluble DNA minor groove binders as potential chemotherapeutic agents: synthesis, characterization, DNA binding and cleavage, antioxidation, cytotoxicity and HSA interactions. Dalton Transaction, 43(2014), DOI: 10.1039/c3dt53577k;

*以上信息由高级会员个人更新和维护。