王金全

男， 广东药科大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

主要工作经历：
1. 2006.09-2008.12 广东药科大学 生命科学与生物制药学院 助教
2. 2009.01-2019.08 广东药科大学 生命科学与生物制药学院 讲师
3. 2019.01-2024.12 广东药科大学 生命科学与生物制药学院 副教授
4. 2024.12-至今 广东药科大学 生命科学与生物制药学院 教授
主要教育经历：
1. 1998.09-2003.07 华北理工大学 公共卫生学院 本科，预防医学
2. 2003.09-2006.07 华北理工大学 公共卫生学院 硕士，药物毒理学
3. 2011.09-2014.12 中山大学 化学学院 博士，化学生物学
4. 2019.09-2020.09 澳大利亚联邦科学院（CSIRO） 访问学者（国家公派）

研究领域和兴趣

主要研究方向为金属配合物及纳米复合物抗肿瘤作用及其机制。

主要业绩

从事金属配合物及纳米复合物抗肿瘤药理毒理学研究。主持各级科研课题7项，其中国家自然科学基金面上项目2项，广东省自然科学基金项目1项，广东省科技厅项目2项，广东省教育厅项目1项，广州市科技计划项目1项。以第一作者/通讯作者发表SCI论文40余篇，累计被引3000余次，H指数31。

代表成果

一、 代表性论文
1. Jun Shu, Hui Jiang, Minwei Lin, Jinzhe Liang, Yukun Zhao, Diqing Luo*, Jinquan Wang*, Hui Chao*, D-Alanine Functionalized Iridium(III) Complexes as Two-Photon Photo-Antibiotics for Bacteria-Specific Ablation in Infected Macrophages, European Journal of Medicinal Chemistry, 294, 117758, 2025 (IF:5.9)
2. Bishu Wang, Xingguo Tang, Chuntao Xiao, Zhijie Yu, Huaben Bo, Jie Wang, Jinquan Wang, Nucleus-targeted ruthenium(II) complex triggers immunogenic cell death and sensitizes melanoma to anti-PD-1 therapy by activating cGAS-STING pathway, Journal of Inorganic Biochemistry, 267,112871, 2025. (IF:4.3)
3. Dan Wang, Jianyang Zhao, Roger J. Mulder, Julian Ratcliffe, Chunru Wang, Bo Wu, Jinquan Wang*, Xiaojuan Hao*, Highly aqueously stable C60‐polymer nanoparticles with excellent photodynamic property for potential cancer treatment, Smart Medicine. 2: e20230033, 2023. (IF:11.6)
4. Yi Rong, Zhongxian Fan, Zhijie Yu, Li Wei, Han Shen, Huaiyi Huang, Xiaojuan Hao, Zizhuo Zhao and Jinquan Wang*, An endoplasmic reticulum-targeting iridium(III) complex induces immunogenic cell death in melanoma cells and enhances anti-PD-1 immunotherapy by remodeling tumor microenvironment, Inorganic Chemistry Frontiers, 10, 5278, 2023. (一区 top，back cover hot paper, IF:7.0)
5. Fangmian Wei, Shi Kuang,Thomas W Rees, Xinxing Liao, Jiangping Liu, Diqing Luo, Jinquan Wang*, Xiting Zhang*, Liangnian Ji, Hui Chao*. Ruthenium(II) complexes coordinated to graphitic carbon nitride: Oxygen self-sufficient photosensitizers which produce multiple ROS for photodynamic therapy in hypoxia. Biomaterials, 276, 121064, 2021. (Co-Correspondent Author, IF: 12.5)
6. Zizhuo Zhao1, Kangqiang Qiu1, Jiangping Liu, Xiaojuan Hao, Jinquan Wang*. Two-photon photodynamic ablation of tumour cells using an RGD peptide-conjugated ruthenium(II) photosensitiser. Chem., Commun., 56, 12542, 2020. (Correspondent Author，IF: 6.2)
7. Zi-Zhuo Zhao1, Jia-Yi Wu1, Xiao-Di. Liu1, Ming Liang, Xin-Chuan Zhou, Shi Ouyang, Ji-Yi Yao, Jin-Quan Wang*, Bao-Ming Luo*, Insufficient radiofrequency ablation promotes proliferation of residual hepatocellular carcinoma via autophagy. Cancer Lett, 421: 73-81, 2018. (Co-Correspondent Author, IF: 9.7)
8. Jin-Quan Wang*, Jun-Feng Kou, Zi-Zhuo Zhao, Kang-Qiang Qiu, Hui Chao*. Anthraquinone-bridged diruthenium(II) complexes inhibit migration and invasion of human hepatocarcinoma MHCC97-H cells, Inorg. Chem. Front., 4: 1003-1012, 2017. (IF：7.0)
9. Ping-Yu Zhang1, Jin-Quan Wang1, Huai-Yi Huang, Bo-Le Yu, Kang-Qiang Qiu, Shu-Tao Wang, Lei Jiang, Gilles Gasser, Liang-Nian Jia, Hui Chao*. Unexpected high photothemal conversion efficiency of gold nanospheres upon grafting with two-photon luminescent ruthenium(II) complexes: A way towards cancer therapy? Biomaterials, 63: 102-114, 2015. (Co-First Author, IF: 12.5)
10. Ping-Yu Zhang1, Jin-Quan Wang1, Huai-Yi Huang, Hong-Ming Chen, Rui-Lin Guan, Yu Chen, Liang-Nian Ji, Hui Chao*. RuNH2@AuNPs as two-photon luminescent probes for thiols in living cells and tissues. Biomaterials, 35, 9003-9011, 2014. (Co-First Author, IF: 12.5)

二、专利
1. 王金全，乔爱敏，郭舜文，卢晓香，李洁仪，梁楚，方武铨.“一种靶向卵巢癌的钌-LHRH偶联诊疗探针及其制备方法和应用”，中国发明专利（授权专利号）：ZL 2021 1 0302129.8
2. 王金全，薄华本“一种钌配合物、钌-RGD肽偶联物及其制备方法和应用”，中国发明专利（授权专利号）：201810290720.4.

*以上信息由高级会员个人更新和维护。