孙健

男， 新疆医科大学药学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

2000.09 至 2004.06，吉林大学 化学 学士
2004.07 至 2006.08，中国医科大学 基础医学院 助教
2006.08 至 2011.06，吉林大学 物理化学 博士
2011.07 至 2013.12，中国科学院长春应用化学研究所 博士后
2014.01 至 2015.12，中国科学院长春应用化学研究所 助理研究员
2015.12 至 2023.06，中国科学院长春应用化学研究所 副研究员
2023.06 至 2023.11，新疆医科大学 药学院 副研究员
2023.12 至 今， 新疆医科大学 药学院 教授 博士生导师

研究领域和兴趣

药物分析，中药现代化

主要业绩

针对药物治疗与生命分析中催化作用调控问题开展交叉研究工作：1）药物分析与抑制剂药物筛选；2）结构仿生药物制剂；3）疾病标志物检测。以第一或通讯作者在Anal. Chem.（20），Bioact. Mater.等发表SCI论文70余篇，他引3200次，H指数36，科睿唯安2024年度“全球高被引科学家”，2020年至今连续6年入选斯坦福大学发布的全球前2%顶尖科学家榜单。以第一发明人授权中国发明专利4项，主持国家自然科学基金面上、青年项目，自治区杰出青年基金等，参与国家自然科学基金重点项目，入选中国科学院青年创新促进会会员，自治区领军人才。任《Chinese Chemical Letters》、《分析化学》、《Journal of Analysis and Testing》等期刊青年编委。

代表成果

1. Jadera Talap, Dan Tang Yu Wang, Jian Sun*, Haji Akber Aisa*, Smartphone-assisted colorimetric detection of FEN1 and its inhibitors via RCA-magnetic beads-urease cascade amplification, Biosens. Bioelectron., 2025, 290, 117969.
2. Xianqing Tang, Hua Zhang, Jinghuang Chen, Donghui Wu, Yu Wang, Jian Sun*, Zhenxin Wang, Xiurong Yang*, Ferrous Tungstate Nanomaterials with Excellent Enzyme-Mimicking Activity to Enhance Lateral Flow Immunoassay Sensitivity, Anal. Chem., 2025, 97, 2714–2723.
3. Jinghuang Chen, Xianqing Tang, Qihan Sun, Xin Jia, Xingbo Wang, Zhendong Liu, Xu Zhang, Haijiao Xu, Fan Yang, Jian Sun*, Xiurong Yang*, Nucleotide coordinated polymers, a ROS-based immunomodulatory antimicrobial, doubly kill Pseudomonas aeruginosa biofilms of implant infections, Bioact. Mater., 2025, 44, 461–473.
4. Donghui Wu, Qilin Zhao, Yu Wang, Bing Zhang, Xianqing Tang, Jadera Talap, Jian Sun*, Xiurong Yang*, Fluorescent Iron-Doped Polymer Dot Nanozyme-Based Cascade System for Dual-Mode Detection of Acetylcholinesterase Activity and Its Inhibitors, Anal. Chem., 2024, 96, 15682–15691.
5. Qilin Zhao, Donghui Wu, Yu Wang, Tian Meng, Jian Sun*, Xiurong Yang*, Encapsulation of Enzymes into Hydrophilic and Biocompatible Metal Azolate Framework: Improved Functions of Biocatalyst in Cascade Reactions and Its Sensing Applications, Small, 2024, 20, 2307192.
6. Donghui Wu, Qilin Zhao, Bing Zhang, Xianqing Tang, Yushu Li, Jian Sun*, Xiurong Yang*, Iron Doped Polymer Dots with Enhanced Fluorescence and Dual Enzyme Activity for Versatile Bioassays, Anal. Chem., 2024, 96, 2929–2938.
7. Xianqing Tang, Jinghuang Chen, Mengqian Zhang, Jian Sun*, and Xiurong Yang*, Tunable catalytic activity of FeWO4 nanomaterials for sensitive assays of pyrophosphate ion and alkaline phosphatase activity, Sci. China Chem., 2023, 66, 1860−1868.
8. Lixia Lu*, Xinyu Shao, Xiaoxiao Lin, Linhe Ding, Bingchan Song, Jian Sun*, Tb3+-xylenol orange complex-based colorimetric and luminometric dual-readout sensing platform for dipicolinic acid and metal ions, Chin. Chem. Lett., 2023, 34, 107203.
9. Yu Wang, Yu Xue, Qilin Zhao, Shuang Wang, Jian Sun*, Xiurong Yang*, Colorimetric Assay for Acetylcholinesterase Activity and Inhibitor Screening Based on Metal–Organic Framework Nanosheets, Anal. Chem., 2022, 94, 16345−16352.
10. Chenghui Zhang‡, Chuanxia Chen‡, Dan Zhao, Ge Kang, Fangning Liu, Fan Yang, Yizhong Lu*, and Jian Sun*, Multienzyme Cascades Based on Highly Efficient Metal–Nitrogen–Carbon Nanozymes for Construction of Versatile Bioassays, Anal. Chem., 2022, 94, 3485−3493.

*以上信息由高级会员个人更新和维护。