郭玮炜

男， 南开大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

1999-2003 吉林大学 化学学院 理学学士
2004-2010 中国科学院长春应用化学研究所 理学博士
2010-2011 中国科学院长春应用化学研究所 科研助理
2011-2015 以色列耶路撒冷希伯来大学 博士后
2015.11-2022.11 南开大学 化学学院 研究员 博士生导师
2022.11-至今 南开大学 化学学院 教授 博士生导师

研究领域和兴趣

生物分析、智能生物水凝胶材料、荧光纳米簇、DNA纳米技术

主要业绩

郭玮炜教授致力于发展基于软材料的智能生化分离分析方法和装置，通过研究具备多功能可编码的水凝胶、薄膜和微纳结构等柔性分离传感材料及其与纳米团簇、量子点和功能二维结构等结合的复合功能传感材料的结构设计、构效调控与相关基础科学问题，建立和发展针对不同类型生化分析目标的分离检测新原理与新方法，进而发展智能的生化分析试纸与芯片、穿戴式生化传感器和植入式诊疗一体化系统，目前已经取得了一系列创新研究成果，发表论文60余篇，引用5100多次。其中，以第一或通讯作者在Sci. Adv., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Adv. Mater.等期刊发表论文40篇，最高单篇他引超过700次，多篇入选ESI高被引论文或期刊封面与VIP文章。此外，担任中文核心期刊《分析试验室》编委（第五届），担任《SmartMat》、《Journal of Analysis and Testing》、《分析化学》、《应用化学》等期刊青年编委，先后主持国家“万人计划”青年拔尖人才项目、国家自然科学基金青年与面上项目、天津市自然科学基金重点项目以及南开大学百青项目等多项。

代表成果

1. 代表性论文
(1) Hanxue Liang, Yali Mu, Mengyuan Yin, Ping-Ping He, Weiwei Guo*, Solar-Powered Simultaneous Highly Efficient Seawater Desalination and Highly Specific Target Extraction with Smart DNA Hydrogels, Sci. Adv. 2023, 9, eadj1677, DOI: 10.1126/sciadv.adj1677.
(2) Yali Mu, Xiaowen Wang, Xiaoxue Du, Ping-Ping He, Weiwei Guo*, DNA Cryogels with Anisotropic Mechanical and Responsive Properties for Specific Cell Capture and Release. J. Am. Chem. Soc. 2024, 146, 5998–6005, DOI: 10.1021/jacs.3c12846.
(3) Yaxing Zhang, Chunyan Wang, Mengyuan Yin, Hanxue Liang, Qi Gao, Shanjin Hu, Weiwei Guo*, Liquid Metal Nanocores Initiated Construction of Smart DNA-Polymer Microgels with Programmable and Regulable Functions and Near-Infrared Light-Driven Locomotion, Angew. Chem. Int. Ed. 2024, 63, e202311678, DOI: 10.1002/anie.202311678.
(4) Xiaoxue Du, Ping-Ping He, Chunyan Wang, Xiaowen Wang, Yali Mu, Weiwei Guo*, Fast Transport and Transformation of Biomacromolecular Substances via Thermo-Stimulated Active “Inhalation–Exhalation” Cycles of Hierarchically Structured Smart pNIPAM–DNA Hydrogels, Adv. Mater. 2023, 35, 2206302, DOI: 10.1002/adma.202206302.
(5) Fengyun Li, Danya Lyu, Shuo Liu, Weiwei Guo*, DNA Hydrogels and Microgels for Biosensing and Biomedical Applications, Adv. Mater. 2020, 32, 1806538, DOI: 10.1002/adma.201806538.
(6) Jingrun Ran, Weiwei Guo*, Hailong Wang, Bicheng Zhu, Jiaguo Yu, Shi-Zhang Qiao*, Metal-Free 2D/2D Phosphorene/g-C3N4 Van der Waals Heterojunction for Highly Enhanced Visible-Light Photocatalytic H2 Production, Adv. Mater. 2018, 30, 1800128, DOI: 10.1002/adma.201800128.
(7) Jingtao Wang#, Pingping Chen#, Benbing Shi, Weiwei Guo*, Mietek Jaroniec, Shi-Zhang Qiao*, Regularly Channeled Lamellar Membrane for Unparalleled Water and Organics Permeation, Angew. Chem. Int. Ed. 2018, 57, 6814-6818, DOI: 10.1002/anie.201801094.
(8) Weiwei Guo#, Chun-Hua Lu#, Ron Orbach, Fuan Wang, Xiu-Juan Qi, Alessandro Cecconello, Dror Seliktar, Itamar, Willner*, pH-Stimulated DNA Hydrogels Exhibiting Shape-Memory Properties, Adv. Mater. 2015, 27, 73-78, DOI: 10.1002/adma.201403702.
(9) Weiwei Guo#, Chun-Hua Lu#, Xiu-Juan Qi, Ron Orbach, Michael Fadeev, Huang-Hao Yang, Itamar Willner*, Switchable Bifunctional Stimuli-Triggered Poly-N-Isopropylacrylamide/DNA Hydrogels, Angew. Chem. Int. Ed. 2014, 53, 10134–10138, DOI: 10.1002/anie.201405692.
(10) Weiwei Guo, Jipei Yuan, Qingzhe Dong, Erkang Wang*, Highly sequence-dependent formation of fluorescent silver nanoclusters in hybridized DNA duplexes for single nucleotide mutation identification, J. Am. Chem. Soc. 2010, 132, 932-934, DOI: 10.1021/ja907075s.

2. 专利
(1). 发明人：郭玮炜、程苑、贺平平；基于光诱导质子转移过程的光响应DNA水凝胶的制备方法；专利号：ZL 2021 1 0801187.5；专利申请日：2021.07.15；授权公告日：2022.05.13；授权公告号：CN 113501905 B
(2). 发明人：郭玮炜、杜晓雪；一种具有大孔结构的高强度DNA水凝胶的制备方法；专利号：ZL 2020 1 0698755.9；专利申请日：2020.07.20；授权公告日：2022.11.04；授权公告号：CN 111793239 B
(3). 发明人：郭玮炜、陈子春、韩翠燕；一种磁性荧光双功能纳米材料的制备方法；专利号：ZL 2020 1 0698774.1；专利申请日：2020.07.20；授权公告日：2023.04.28；授权公告号：CN 111849478 B

3. 重要学术会议邀请报告
(1) Weiwei Guo; Enhancing the Performance of Smart DNA Hydrogels via Active, Rapid and High-Degree Swelling-Shrinkage Cycles; 2023; The 9th International Conference on Nanoscience and Technology (ChinaNANO2023); 北京.
(2) Weiwei Guo; Biosensing applications of DNA based functional materials; 2019; The 8th International Conference on Nanoscience and Technology (ChinaNANO2019), 北京.
(3) Weiwei Guo; Construction and Applications of Smart Hydrogels Undergoing Active and Fast "Swelling-Shrinkage" Cycles with High Volume Ratios (I-20); 2023; The Nineteenth International Symposium on Electroanalytical Chemistry (19th ISEAC), 长春.
(4) 郭玮炜; Studies of fluorescent DNA silver nanoclusters and smart DNA hydrogels; 2017; 第十二届中美华人纳米论坛 (The 12th Sino-US Nano Symposium); 北京.
(5) 郭玮炜; 智能柔性分离传感体系; 2024; 中国化学会第34届学术年会; 广州.

*以上信息由高级会员个人更新和维护。