乔娟

女， 北京石油化工学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

2007.9-2010.6 中国科学院化学研究所/博士研究生
2010.7-2013.6 中国科学院化学研究所/活体分析化学实验室 助理研究员
2013.7-2022.8 中国科学院化学研究所/活体分析化学实验室 副研究员
2018.1-2018.3 美国马萨诸塞大学阿默斯特分校/化学系 访问学者
2016.9-2022.12 中国科学院大学/化学工程学院 兼职岗位教师/分析化学助教
2022.9-至今 北京石油化工学院/新材料与化工学院 教授

研究领域和兴趣

聚合物制备及其在活体分析化学中的应用

主要业绩

博士生导师，研究领域为智能聚合物制备及生物药物分析。美国麻省大学阿默斯特分校和韩国浦项科技大学访问学者，北京色谱协会理事、北京核酸适配体交叉技术学会理事、中国分析测试协会毒物分析分会委员。承担国家自然科学基金4项、北京市自然科学基金1项。在Anal. Chem.，Biosens. Bioelectron.等学术期刊上共发表SCI论文100余篇，H因子29，授权专利3项；参编专著2部；获中国分析测试协会科学技术奖一等奖2项。
I. 主要研究工作
1. 毛细管电泳手性药物分析研究
2. 温敏荧光聚合物的制备及其细胞内温度成像应用研究
3. 靶向识别/原位可控聚合物酶反应器的制备及其蛋白酶解研究
II. 奖励与荣誉
1. 齐莉，乔娟，木肖玉，李楠，陈义. 构建聚合物分子温度计及其细胞成像应用研究，中国分析测试协会科学技术奖一等奖，2016年。
2. 齐莉，乔娟，张海枝，姚春荷，沈莹，木肖玉，张荣月，辛培勇，魏晓奕，李雅萍，陈义. 基于蛋白质及手性氨基酸分析的生物色谱新方法研究，中国分析测试协会科学技术奖一等奖，2012年。
III. 承担科研项目
1. 北京市自然科学基金面上项目
2. 国家自然科学基金面上项目
3. 国家自然科学基金重大研究计划培育项目
4. 国家自然科学基金青年基金项目
5. 北京石油化工学院致远科研基金

代表成果

IV. 代表性学术论文
1. Shidi Zhang, Li Qi,* Rui Yao, Zhenwen Zhao, Fangna Gu, Juan Qiao*, Thermo-Responsive Polymer/Cerium−Gold Nanoparticle-Decorated UiO-66-NH2 Nanozymes for Colorimetric Sensing of Captopril, ACS Applied Nano Materials, 2026, 9, 3792-3801.
2. Bowen Zhou, Li Qi*, Yutong Liu, Yushi Zhou, Juan Qiao*, Confining AuNPs on mesoporous MOFs towards enhanced catalytic activity for visual monitoring of L-cysteine, Inorganic Chemistry Communications, 2026, 187, 116404.
3. Meng Yang, Qiong Wang, Xinle Wang, Chuanfang Chen, Cai Liu, Juan Qiao*, Encapsulating gold nanoclusters into zinc-glutamate metal organic frameworks for ferric ions detection in zebrafish embryos, Microchimica acta, 2026, 193, 187.
4. Yan Zhang, Zexi Yu, Xiaotong Zhu, Rongyue Zhang, Nan Li, Min Wang, Juan Qiao *. γ-cyclodextrin based metal organic framework as micellar electrokinetic chromatography additive for the chiral separation of dansylated amino acids, Journal of Chromatography B, 2026:1268, 124839.
5. Shufan Ge, Xiaotong Zhu, Chuanfang Chen, Rongyue Zhang, Min Wang, Nan Li, Xiaonan He, Juan Qiao*, Fluorescence polymer thermometer for the real-time mitochondrial temperature imaging of zebrafish embryos and larvae, Dyes and Pigments, 2026, 246, 113309.
6. Xiaotong Zhu, Xinyu Li, Haozhe Liu, Rongyue Zhang, Nan Li, Min Wang, Xiaonan He, Yunliang He, Juan Qiao*, A fluorescence-colorimetric dual-signal sensing platform based on arginine@ATT-AuNCs for ascorbic acid metabolic analysis in mice, Microchemical Journal 2025, 218, 115777.
7. Meng Yang, Xiaotong Zhu, Rongyue Zhang, Zhenwen Zhao, Li Qi, Min Wang, Nan Li, Juan Qiao*, Construction of AuNCs@MOF and Lead Ions Metabolic Analysis in Rat Serum, Inorganic Chemistry Communications, 2025, 178, 114517.
8. Xiaotong Zhu, Xinyu Li, Li Qi, Rongyue Zhang, Nan Li, Xiaonan He, Juan Qiao*, Protein@AuNPs synthesized by microfluidic droplet system and application in Cu(II) and L-Cysteine sensing[J], Chemical Research in Chinese Universities, 2025, 41, 131-137.
9. Xiaotong Zhu, Rongyue Zhang, Yucong Wang, Hongxia Jia*, Juan Qiao*, Fluorescence-enhanced MOF-encapsulated AuNCs for highly sensitive detection of melanin[J], Inorganic Chemistry Communications, 2024, 113226.
10. Juan Qiao, § Cheng Cheng, § Dan Li, Li Qi*, Thermo-responsive polymer-modified metal–organic frameworks as soft–rigid enzyme-reactors for enhancement of enzymolysis efficiency using a controllable embedding protocol[J], Journal of Materials Chemistry B, 2023, 11, 6428.
11. Juan Qiao,§ Qian Ma,§ Cheng Cheng, and Li Qi*, Fabrication of Dual-Stimuli-Responsive Polymer Vesicles for Regulation of Enzymolysis Efficiency in A Cascade Reaction[J], Chemistry An Asian Journal, 2023, 18, e202300285.
12. Juan Qiao,§ Xinya Zhang,§ Cheng Cheng, Li Qi*, Thermo-sensitive Porous Polymer Membrane-immobilized Cellulose as a Switchable Enzyme Reactor for Tuning Its Enzymolysis via Variation Temperature[J], Chemical Research in Chinese Universities, 2023, 39(6), 992-997.
13. Juan Qiao, Qian Ma, Xiangfei Li, Li Qi*, Redox-responsive polymer nanoreactors based on methionine sulfoxide for monitoring cell adhesion [J]. Analytical Chemistry, 2022, 94, 11807-11812.
14. Juan Qiao, Xiangfei Li, Li Qi*, Fluorescent polymer-modified gold nanobipyramids for temperature sensing during photothermal therapy in living cells [J]. Chinese Chemical Letters, 2022, 33, 3193-3196.
15. Juan Qiao, Yuying Song, Chuanfang Chen, Li Qi*, In situ determination of sialic acid on cell-surface with pH-regulated polymer enzyme nanoreactor [J]. Analytical Chemistry, 2021, 93, 7317-7322.
16. Juan Qiao, Deyu Wu, Yuying Song, Wenliang Ji, Qingwei Yue, Lanqun Mao, Li Qi*, Simultaneous monitoring of intracellular temperature and norepinephrine variation by fluorescent probes during norepinephrine reuptake [J]. Analytical Chemistry, 2021, 93, 14743-14747.
17. Juan Qiao, Lili Liu, Ji Shen, Li Qi*, Enzyme immobilization on a pH-responsive porous polymer membrane for enzymatic kinetics study [J]. Chinese Chemical Letters, 2021, 32, 3195-3198.
18. Juan Qiao, Li Qi*, Recent progress in plant-gold nanoparticles fabrication methods and bioapplications [J]. Talanta, 2021, 223, 121396.
19. Juan Qiao, Han Wu, Huan Wei, Lanqun Mao, Tie Wang, Li Qi*, Selective capture and in-situ controllable detection of D-glucose in cerebral systems [J]. Analytical Chemistry, 2020, 92, 4445-4450.
20. Juan Qiao, Yoon-Ho Hwang, Dong-Pyo Kim, Li Qi*, Simultaneous monitoring of temperature and Ca2+ concentration variation by fluorescent polymer during intracellular heat production [J]. Analytical Chemistry, 2020, 92, 8579-8583.
21. Juan Qiao, Junfang Jiang, Lili Liu, Ji Shen, Li Qi*, Enzyme reactor based on reversible pH controlled catalytic polymer porous membrane [J]. ACS Applied Materials & Interfaces, 2019, 11, 15133-15140.
22. Juan Qiao, Qianrong Liu, Han Wu, Huiwu Cai, Li Qi*, Non-enzymatic detection of serum glucose using a fluorescent nanopolymer probe [J]. Microchimica Acta, 2019, 186, 366.
23. Juan Qiao, Liping Zhao, Lili Liu, Li Qi*, L-Glutaminase enzyme reactor based on porous bamboo sticks and its application in enzyme inhibiters screening [J].Talanta, 2019, 205, 120126.
24. Wenya Feng, Juan Qiao*, Dan Li, Li Qi*, Chiral ligand exchange capillary electrochromatography with dual ligands for enantioseparation of D,L-amino acids [J].Talanta, 2019, 194, 430-436.
25. Juan Qiao, Chuanfang Chen, Dihua Shangguan, Xiaoyu Mu, Shutao Wang, Lei Jiang*, Li Qi*, Simultaneous monitoring of mitochondrial temperature and ATP fluctuation using fluorescent probes in living cells [J]. Analytical Chemistry, 2018, 90, 12553-12558.
V. 发明专利和软件著作权
1. 乔娟，曹俊阳，张竞丹，李浩玉，张荣月，一种聚合物修饰环糊精MOFs材料及其制备方法和毛细管电泳手性分离方法，中华人民共和国发明专利, ZL202311609129.8
2. 齐莉, 沈吉, 乔娟, 刺激响应聚合物基质D-氨基酸氧化酶反应器的制备及其酶解效率调控方法，中华人民共和国发明专利, ZL202110463264
3. 齐莉, 乔娟, 李雅萍, 木肖玉, 一种固定化L-天冬酰胺酶反应器，中华人民共和国发明专利, ZL201210137793.2
VI. 出版著作
1. 王可，乔娟，《光学探针与传感分析》马会民主编 (第11章), 2020, 448-472
2. Juan Qiao, Li Qi. Design and preparation of stimuli-responsive AIE fluorescent polymers-based probes for cells imaging, Handbook of Aggregation, 2022

*以上信息由高级会员个人更新和维护。