王彦恩

男， 河北农业大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

2000.09-2004.06 廊坊师范学院化学专业 本科
2004.09-2007.06 南京师范大学物理化学专业 硕士研究生
2013.09-2017.06 河北大学高分子化学与物理专业 博士研究生
2018.11-2022.05 河北农业大学植物保护学流动站 博士后
2007.08至今 河北农业大学 实验师-高级实验师-教授

研究领域和兴趣

有机化学，新农药创制

主要业绩

王彦恩，男，1981年11月生，中共党员，任教于河北农业大学理学院，教授，硕士研究生导师，博士，优秀博士后。近年来，一直从事基于新靶标的新型除草剂创制的研究，在计算机辅助农药分子设计、合成、除草活性评价及作用机制研究等方面取得了一些科研成果。主持或主要参与国家自然科学基金3项，主持河北省高层次人才资助项目1项，河北省自然科学基金面上项目1项，担任Pesticide Biochemistry and Physiology, Arabin Journal of Chemistry, Current Medicinal Chemistry等国际期刊审稿人，及中国国际“互联网+”大赛评审专家。已发表SCI 论文30余篇，其中在农药领域的权威期刊J. Agric. Food Chem.上发表7篇，在有机化学领域 Nat. Commun.发表1篇；一区期刊Org. Lett. 上发表5篇；一区期刊Org. Chem. Front.上发表1篇；二区Top期刊J. Org. Chem.上发表6篇等，申请国家发明专利5件，已获授权3件。获得省科技进步二等奖1项、保定市科技进步二等奖1项、校级自然科学奖2项，指导学生参加 “挑战杯”科技作品竞赛、“互联网+”大学生创新创业大赛等多项国家一级赛事，获得多项省级以上奖励。

代表成果

1. 论文：
1. Chengkun Li; Junmin Wang; Haijiao Dong; Dongchen Yang; Peng Li; Shuang Cao; Chao Li; Zexiu An; Jinlin Zhang;* Yan-En Wang*. Design, Synthesis, and Herbicidal Activity Study of Novel Pyrazole-Carboxamides as Potential Transketolase Inhibitors[J]. Journal of Agricultural and Food Chemistry, 2025, 73(1): 216–225.（中科院一区Top期刊，影响因子：5.7，通讯作者）
2. Dongchen Yang; Yan-En Wang;* Miaomiao Chen; Haiyan Liu; Jingqian Huo; Jinlin Zhang*. Discovery of bis-5-cyclopropylisoxazole-4-carboxamides as novel potential 4-hydroxyphenylpyruvate dioxygenase inhibitors[J]. Journal of Agricultural and Food Chemistry, 2023, 71(13): 5136−5142.（中科院一区Top期刊，影响因子：6.1，共一，通讯作者）
3. Wang Yan-En; Yang Dongchen; Dai Longtao; Huo Jingqian; Chen Lai; Kang Zhanhai; Mao Jianyou; Zhang Jinlin*. Design, synthesis, herbicidal activity and molecular docking study of 2-thioether-5-(thienyl/pyridyl)-1,3,4-oxadiazoles as potent transketolase inhibitors[J]. Journal of Agricultural and Food Chemistry, 2022, 70(8): 2510−2519. （中科院一区Top期刊，影响因子：5.895，第一）
4. Yan-En Wang; Dongchen Yang; Chujian Ma; Shiqi Hu; Jingqian Huo; Lai Chen; Zhanhai Kang;Jianyou Mao; Jinlin Zhang*; Design, synthesis, and herbicidal activity of naphthalimide–aroyl hybrids as potent transketolase inhibitors[J]. Journal of Agricultural and Food Chemistry, 2022, 70(40): 12819−12829. （中科院一区Top期刊，影响因子：5.895，第一）
5. Wang Yan-En; Yang Dongchen; Huo Jingqian; Chen Lai; Kang Zhanhai; Mao Jianyou; Zhang Jinlin*. Design, synthesis, and herbicidal activity of thioether containing 1,2,4-triazole Schiff bases as transketolase inhibitors[J]. Journal of Agricultural and Food Chemistry, 2021, 69(40): 11773−11780. （中科院一区Top期刊，影响因子：5.895，第一）
6. Shiqi Hu; Yanen Wang; Kai Wang; Dongchen Yang; Lai Chen; Zexiu An; Jingqian Huo;* Jinlin Zhang.* Design, synthesis, and herbicidal activity of pyrazole amide derivatives as potential transketolase inhibitors[J]. Journal of Agricultural and Food Chemistry, 2024, 72(7): 3334–3341.
7. Mingyu Jiang; Yan-En Wang; Yuanyun Gu; Ruyuan Ma; Dan Xiong; Patrick J. Walsh; Jianyou Mao*. Smiles-rearrangement-Based one-Pot synthesis of diarylacetylenesfrom benzylic sulfones and methyl benzoates mediated by LiN(SiMe3)2/KN(SiMe3)2[J]. Organic Letters, 2024, 26(24), 5082−5086. （中科院一区Top期刊，影响因子：5.2）
8. Ma Ruyuan; Wang Yan-En; Xiong Dan; Mao Jianyou*. A tandem madelung indole synthesis mediated by a LiN(SiMe3)2/CsF system[J]. Organic Letters, 2023, 25 (41): 7557-7561. （中科院一区Top期刊，影响因子：6.072）
9. Qian Pengcheng; Guan Haixing; Wang Yan-En; Lu Qianqian; Zhang Fan; Xiong Dan; Walsh Patrick J.; Mao Jianyou*. Catalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis[J]. Nature Communications, 2021, 12(1): 6613.（Nature子刊，影响因子：17.694）
10. Yuanyun Gu; Yan-En Wang; Yaqi Yuan; Haodong Xu; Yizhou Lu; Yufei Zhang; Fei Xue; Dan Xiong; Jianyou Mao*. Alkali–amide-catalyzed one-pot aminoallylation of aldehydes with allylbenzenes[J]. The Journal of Organic Chemistry, 2023, 88(11): 7362–7372.（中科院二区Top期刊，影响因子：4.198）
11. Chujian Ma, Luyang Tian, Yan-En Wang, Jingqian Huo, Zexiu An, Susu Sun, Song Kou, Wenfei Wang, Yaze Li, Jinlin Zhang*, and Lai Chen* Discovery of novel pyrazole acyl thiourea skeleton analogue as potential herbicide candidates[J]. Journal of Agricultural and Food Chemistry, 2024, 72, 7727-7734.
12. Ma, Ruyuan; Gu, Yuanyun; Wang, Yan-En; Fei, Rongbi; Xiong, Dan; Mao, Jianyou*, One-Pot Synthesis of Indolin-3-ones Mediated by LiN(SiMe3)2/CsF[J]. Org. Lett. 2024, 26(24), 5082−5086. （中科院一区Top期刊，影响因子：5.2）
13. Zheng, Jiali; Hua, Rui; Wang, Yan-En; Lin, Tingzhi; Ou, Mingjie; Wu, Yu; Shi, En-hao; He, Jing; Xiong, Dan; Mao, Jianyou*, Synthesis of homoallylamines enabled by cobalt or palladium catalyzed allylic substitution of azaarylmethylamines[J]. Org. Lett. 2024, 26(15), 2982−2986.
14. Liu, Qiang; Lin, Tingzhi; Wang, Yan-En; Liang, Wenbiao; Cao, Liuying; Sheng, Xutao; Xiong, Dan; Mao, Jianyou. Nickel-catalyzed reductive arylation of alpha-bromo sulfoxide[J]. Organic Letters, 2023, 25(51): 9153–9157. （中科院一区Top期刊，影响因子：6.072）
15. Tingzhi Lin; Yan-En Wang; Ning Cui; Miaohui Li; Rui Wang; Jiahui Bai; YiRan Fan; Dan Xiong; Fei Xue; Patrick J. Walsh; Jianyou Mao*; Nickel-catalyzed cross-electrophile coupling of 1,2,3-benzotriazin-4(3H)-ones with aryl bromides[J]. The Journal of Organic Chemistry, 2022, 87(24): 16567−16577. （中科院二区Top期刊，影响因子：4.198）
16. Tingzhi Lin, Pengcheng Qian, Yan-En Wang, Mingjie Ou, Long Jiang, Chen Zhu, Yuchuan Xu, Dan Xiong, Jianyou Mao*; Palladium-catalyzed direct arylation of 2‑pyridylmethyl silanes with aryl bromides[J]. Organic Letters, 2021, 23(8): 3000−3003. （中科院一区Top期刊，影响因子：6.072）
17. Yuanyun Gu, Zhen Zhang, Yan-En Wang, Ziteng Dai, Yaqi Yuan, Dan Xiong, Jie Li, Patrick J. Walsh, Jianyou Mao*; Benzylic aroylation of toluenes mediated by a LiN(SiMe3)2/Cs+ system[J]. The Journal of Organic Chemistry, 2022, 87(1): 406−418. （中科院二区Top期刊，影响因子：4.198）
18. Bo Ling, Wenjun Yang, Yan-En Wang, Jianyou Mao*; Cooperative N-heterocyclic carbene/palladium-catalyzed umpolung 1,4-addition of vinyl bromides to enals[J]. Organic Letters, 2020, 22(24): 9603−9608.（中科院一区Top期刊，影响因子：6.072）
19. Xinyu Xu, Mingjie Ou, Yan-En Wang, Tingzhi Lin, Dan Xiong, Fei Xue, Patrick J. Walsh* and Jianyou Mao*. Alkali-amide controlled selective synthesis of 7-azaindole and 7-azaindoline through domino reactions of 2-fluoro-3-methylpyridine and aldehydes[J]. Organic Chemistry Frontiers. 2022, 9(9): 2541−2548. （中科院一区Top期刊，影响因子：5.456）
20. Qianqian Lu, Haixing Guan, Yan-En Wang, Dan Xiong, Tingzhi Lin, Fei Xue, and Jianyou Mao*; Nickel/photoredox-catalyzed enantioselective reductive cross-coupling between vinyl bromides and benzyl chlorides[J]. The Journal of Organic Chemistry, 2022, 87(12): 8048−8058. （中科院二区Top期刊，影响因子：4.198）
21. Yaqi Yuan, Yuanyun Gu, Yan-En Wang, Jiali Zheng, Jiaying Ji, Dan Xiong, Fei Xue, and Jianyou Mao; One-pot rapid access to benzyl silanes, germanes, and stannanes from toluenes mediated by a LiN(SiMe3)2/CsCl system[J]. The Journal of Organic Chemistry, 2022, 87(21): 13907−13918. （中科院二区Top期刊，影响因子：4.198，第三）
22. Ning Cui, Tingzhi Lin, Yan-En Wang, Jian Wu, Yuheng Han, Xinyang Xu, Fei Xue, Dan Xiong, Patrick J. Walsh, and Jianyou Mao*. Nickel-catalyzed reductive coupling of γ-metalated ketones with unactivated alkyl bromides[J]. Organic Letters, 2022, 24(22): 3987−3992.
2. 专利：
（1）王彦恩; 张金林; 陈来; 一类1,2,4-三唑席夫碱硫醚衍生物及其制备方法和用途, 2023-1-31, 中国, ZL2020104585467 (授权).
（2）王彦恩; 张金林; 陈来 ; 一类含1,8-萘二甲酰亚胺的三酰基胺衍生物及其制备方法和用途, 2023-02-21, 中国, ZL2020106378762 (授权).
（3）王彦恩; 张金林; 王小清; 一种1,3,4-噁二唑硫醚衍生物及其制备方法和用途, 2024-4-2, 中国, ZL2021102267394 (授权).

*以上信息由高级会员个人更新和维护。