陈自胜

男， 西北农林科技大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

1.学习经历

(1) 2004-09 至 2008-06, 陕西师范大学, 应用化学, 学士

(2) 2008-09 至 2013-06, 兰州大学, 有机化学, 硕士，博士

(3) 2015-01 至 2015-12, 韩国梨花女子大学，博士后

(4) 2018-07 至 2019-06, 北京大学, 访问学者

2.工作经历

(1) 2013-07 至 2016-12, 西北农林科技大学, 理学院, 讲师

(2) 2017-01 至 2021-12, 西北农林科技大学, 化学与药学院, 副教授

(3) 2021-12 至 今, 西北农林科技大学, 化学与药学院, 教授 （破格）

研究领域和兴趣

有机合成

主要业绩

本人主要致力于过渡金属Rh(II)/Pd(0)双催化策略和金属卡宾的催化转化研究。针对具有重要生物活性的天然产物，医药和农药合成方面的科学问题，系统性地开展了基于金属卡宾的烯丙基取代反应研究，高效和高选择性地构建了各种类型的季碳中心，既可以是全碳季碳中心，又可以是O-杂季碳中心。先后主持完成国家自然科学基金面上和青年项目，陕西省自然基金和中央高校基本科研业务费等10项。系列工作以第一作者或通讯作者在 Angew. Chem. Int. Ed., ACS Catalysis, Journal of Catalysis, Org. Lett., Chem. Commun.等国际知名期刊上发表SCI论文20多篇。2016年被评为学校“优秀教师”，2017年入选学校“青年英才”培育计划。2020年获得学校青年教师讲课比赛“二等奖”。2022年入选学校高层次人才计划。担任国家自然科学基金，河南省，安徽省自然基金和教育部学位论文通讯评审专家，Nature Communications, ACS Catalysis等国际权威杂志的审稿人。

代表成果

1. Yu-Hua Song, Xiao-Yan Huang, Bao-Qing Mi, Zhao-Xiang Wang, Fang Yang, Kegong Ji, and Zi-Sheng Chen*，Relay Rh(II)/Pd(0) Dual-Catalyzed Three-Component Allylation of α-Diazo Carbonyl Compounds via Ketene Intermediates:
Construction of All-Carbon Quaternary Centers. Org. Lett. 2025, 27, 6737-6742.

2. De-Xin Song, Yu-Hua Song, Heng-Hua Huang, Xiao-Yan Huang, Fang Yang, Kegong Ji, and Zi-Sheng Chen*, Divergent Reactions of α-Diazo 1,3-Dicarbonyl Compounds with Allylic Carbonates Involving Ketene versus Carbene Intermediates Enabled by Cooperative Rh(II)/Pd(0) Dual Catalysis. Org. Lett. 2024, 26, 7920-7925.

3. Qing Liu, Yang-Ting Ma, Xiao-Yan Huang, Yan-Zhen Li, Fang Yang, Shaukat Ali, Kegong Ji, and Zi-Sheng Chen*, Rh(II)-Catalyzed Chemoselective Oxy-alkynylation of Acceptor-Acceptor Carbenes: Synthesis of C2-Quaternary Alkyne-Substituted 3(2H)-Furanones. Org. Lett. 2023, 25, 4044-4049.

4. Zi-Sheng Chen*, Xiao-Yan Huang, Qing Liu, De-Xin Song, Fang Yang, Kegong Ji. Three-component chemo-selective oxy-allylation of a-diazo carbonyl compounds: Access to a-ternary carboxylic esters. Journal of Catalysis, 2023, 417, 52-56.

5. Ming Cheng, Xiao-Yan Huang, Fang Yang, Dong-Mei Zhao, Kegong Ji, and Zi-Sheng Chen*. Palladium-Catalyzed Carbene Migratory Insertion/Carbonylation Cascade Reaction: Synthesis of 2-Indolones with a C3 All-Carbon Quaternary Center. Org. Lett. 2022, 24, 1237-1242.

6. Qian-Qian Zhou, Ming Cheng, Qing Liu, Bing-Qian Qu, Xiao-Yan Huang, Fang Yang, Kegong Ji, and Zi-Sheng Chen*. Cooperative Rh(II)/Pd(0) Dual Catalysis: Synthesis of Highly Substituted 3(2H)-Furanones with a C2-Quaternary Center via a Cyclization/Allylic Alkylation Cascade of α-Diazo-δ-keto-esters. Org. Lett. 2021, 23, 9151-9156.

7. Xian-Xu Wang, Xiao-Yan Huang, Sen-Hao Lei, Fang Yang, Jin-Ming Gao, Kegong Ji, and Zi-Sheng Chen*, Relay Rh(II)/Pd(0) Dual Catalysis: Synthesis of α-Quaternary β-Keto-Esters via [1,2]-Sigmatropic Rearrangement/Allylic Alkylation Cascade of α-Diazo Tertiary Alcohols. Chem. Comm., 2020, 56, 782-785.

8. Zi-Sheng Chen*, Xiao-Yan Huang, Ling-Hang Chen, Jin-Ming Gao, and Kegong Ji*, Rh(II)/Pd(0) Dual Catalysis: Regiodivergent Transformations of Alkylic Oxonium Ylides. ACS Catalysis. 2017, 7, 7902-7907.

9. Zi-Sheng Chen, Liang-Zhu Huang, Hyun Ji Jeon, Zi Xuan, and Sang-gi Lee*, Cooperative Pd(0)/Rh(II) Dual Catalysis: Interceptive Capturing of π-Allyl Pd(II) Complexes with α-Imino Rh(II) Carbenoids. ACS Catalysis. 2016, 6, 4914-4919.

10. Zi-Sheng Chen, Xin-Hua Duan, Ping-Xin Zhou, Shaukat Ali, Jian-Yi Luo and Yong-Min Liang*. Palladium-Catalyzed Divergent Reactions of α-Diazocarbonyl Compounds with Allylic Esters: Construction of Quaternary Carbon Centers. Angew. Chem. Int. Ed., 2012, 51, 1370-1374.

*以上信息由高级会员个人更新和维护。