徐章润

男， 东北大学理学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

1990.9-1994.7 东北大学 本科
1997.9-2000.3 东北大学 硕士
2001.3-2005.9 东北大学 博士
2000.9-至今 东北大学理学院 讲师、副教授、教授
2015.11-2023.11，东北大学理学院院长
2023.12-至今， 东北大学教务处处长

研究领域和兴趣

微流控分析、光谱分析、生物分析

主要业绩

先后入选教育部新世纪优秀人才支持计划、辽宁省百千万人才工程百人层次、沈阳市高层次人才领军人才。先后主持国家自然科学基金仪器专项项目和国家自然科学基金面上项目7项。在国内外重要学术期刊发表论文120余篇，授权国家发明专利6项，作为主要完成人获辽宁省自然科学一等奖和教育部自然科学一等奖。

代表成果

1. Tingju Ren, Yingzhi Zhang, Yuxiao Tong, Qi Zhang, Tianhao Wang, Yue Wang, Chunguang Yang, Zhangrun Xu*. FRET imaging of glycoRNA on small extracellular vesicles enabling sensitive cancer diagnostics. Nature Communications, 2025, 16: 3391. DOI10.1038/s41467-025-58490-2
2. Tingju Ren, Yingzhi Zhang, Qi Zhang, Meilun Tan, Jiahui Gu, Yuxiao Tong, Yue Wang, Chunguang Yang, Zhangrun Xu*. Accurate cancer diagnosis and treatment monitoring through multiplexed profiling of protein markers on small extracellular vesicles. ACS Nano, 2025, 19: 18630-18643. DOI10.1021/acsnano.5c02864
3. Qi Zhang, Ruofei Ma, Siwen Chen, Ke Cao, Yue Wang, Zhangrun Xu*. Biomineralized and metallized small extracellular vesicles encapsulated in hydrogels for mitochondrial-targeted synergistic tumor therapy. Acta Biomaterialia, 2025, 194: 428-441. DOI10.1016/j.actbio.2025.01.041
4. Qi Zhang, Ruofei Ma, Yingzhi Zhang, Jing Zhao, Yue Wang, Zhangrun Xu*. Dual-aptamer-assisted ratiometric SERS biosensor for ultrasensitive and precise identification of breast cancer exosomes. ACS Sensors, 2023, 8: 875-883. DOI10.1021/acssensors.2c02587
5. Wenqi Ye, Xiaopeng Liu, Ruofei Ma, Chunguang Yang, Zhangrun Xu*. Open-channel microfluidic chip based on shape memory polymer for controllable liquid transport. Lab on a Chip, 2023, 23: 2068-2074. DOI10.1039/d3lc00027c
6. Jie Wang, Xiaopeng Liu, Wanyi Xue, Yunyun Wei, Zhangrun Xu*. Highly sensitive monitoring of telomerase activity in living cells based on rapidly triggered cascade amplification reaction. Biosensors and Bioelectronics, 2022, 216: 114645. DOI10.1016/j.bios.2022.114645
7. Yingzhi Zhang, Yunyun Wei, Peng Liu, Xuan Zhang, Zhangrun Xu*, Xiaodong Tan, Mingli Chen, Jianhua Wang. ICP-MS and photothermal dual-readout assay for ultrasensitive and point-of-care detection of pancreatic cancer exosomes. Analytical Chemistry, 2021, 93: 11540-11546. DOI10.1021/acs.analchem.1c02004
8. Yingzhi Zhang, Junye Jiao, Yunyun Wei, Danni Wang, Chunguang Yang*, Zhangrun Xu*. A plasmonic colorimetric biosensor for sensitive exosome detection via enzyme-induced etching of gold nanobipyramid@MnO2 nanosheet nanostructures. Analytical Chemistry, 2020, 92: 15244-15252. DOI10.1021/acs.analchem.0c04136
9. Yue Wang, Jing Liu, Yukihiro Ozaki*, Zhangrun Xu*, Bing Zhao*. Effect of TiO2 on altering direction of interfacial charge transfer in a TiO2-Ag-MPY-FePc system by SERS. Angewandte Chemie International Edition, 2019, 131: 8256-8260. DOI10.1002/anie.201900589
10. Danni Wang, Rui Guo, Yunyun Wei, Yingzhi Zhang, Xiayu Zhao, Zhangrun Xu*. Sensitive multicolor visual detection of telomerase activity based on catalytic hairpin assembly and etching of Au nanorods. Biosensors and Bioelectronics, 2018, 122: 247-253. DOI10.1016/j.bios.2018.09.064

*以上信息由高级会员个人更新和维护。