燕云峰

男， 浙江工业大学生物工程学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

2017.03-至今， 浙江工业大学生物工程学院，教授
20120.8-2017.01，University of Texas Southwestern Medical Center, Research Scientist
2011.03-2012.07， University of Massachusetts Amherst, Postdoc
2009.10-2011.02，上海师范大学化学系，讲师
2007.07-2009.09，复旦大学高分子科学系，博士后
2002.09-2007.06，中国科学技术大学化学物理系，博士
1998.09-2002.06，安徽师范大学化学系，本科

研究领域和兴趣

高分子化学、生物材料、基因治疗和生物医学

主要业绩

研究工作聚焦生物材料和纳米生物药物领域。主持国家自然科学基金联合基金、面上项目和浙江省自然科学基金重点项目等多项。在PNAS, Biomaterials等知名期刊发表论文六十余篇，授权中国发明专利4项。担任中国感光学会生物基功能大分子材料与技术专业委员会委员，长期担任Nat. Commun., J. Mater. Chem. B, Chem. Commun., Acs Appl. Mater. Inter. Sci., Acta Biomater.等主流期刊审稿人。

代表成果

1. Yichen Li, Yi Cao, Hao Bai, Luwei Zhang, Baiqiu Chen, Chengfan Wu, Qi Shuai, and Yunfeng Yan* Incorporation of disulfide bonds into ionizable lipids enables efficient splenic mRNA delivery and potent immunotherapy in mice. Chemical Engineering Journal 2025, 516, 164285
2. Yuduo Gao, Luwei Zhang, Ziyue Wang, Hao Bai, Chengfan Wu, Qi Shuai, and Yunfeng Yan* Enhanced Pulmonary and Splenic mRNA Delivery Using DOTAP-Incorporated Poly(beta-Amino Ester)-Lipid Nanoparticles. Biomacromolecules 2025, 26(1), 623-634
3. Pingge Jiang, Yaxuan Wang, Qiong Wu, Ziyue Wang, Chengfan Wu, Qi Shuai, and Yunfeng Yan* Development of diselenide-containing poly(β-amino ester)s for potent mRNA delivery to the spleen. Biomacromolecules 2025, accepted
4. Chengfan Wu, Pingge Jiang, Wen Su, and Yunfeng Yan* Alkaline Phosphatase-Instructed Peptide Assemblies for Imaging and Therapeutic Applications. Biomacromolecules 2024, 25(9), 5609–5629
5. Qi Shuai, Wanxuan Xie, Siyuan Chen, Huahui Su and Yunfeng Yan* Novel aromatic moieties-modified poly(glycidyl amine)s with potent siRNA delivery and cancer treatment effect. Journal of Materials Chemistry B 2024, 12, 3115
6. Wenfei Qian, Hao Bai, Yunfeng Yan*, and Qing Bi Regulation of Physicochemical Properties of Alginate-based Hydrogels and Preliminary Applications in Wound Healing. International Journal of Biological Macromolecules 2024, 283, 137627
7. Yunfeng Yan,* Xiaomin Liu, Longyu Wang, Chengfan Wu, Qi Shuai, Yanmei Zhang, and Shuai Liu Branched Hydrophobic Tails in Lipid Nanoparticles Enhance mRNA Delivery for Cancer Immunotherapy. Biomaterials 2023, 301, 122279
8. Wenbo Ye, Fangtao Zhu, Yue Cai, Longyu Wang, Guangliang Zhang, Guangkuo Zhao, Xiaohe Chu, Qi Shuai, Yunfeng Yan* Improved paclitaxel delivery with PEG-b-PLA/zein nanoparticles prepared via flash nanoprecipitation. International Journal of Biological Macromolecules 2022, 221, 486-495
9. Qi Shuai, Fangtao Zhu, Mengdan Zhao, YunfengYan* mRNA delivery via non-viral carriers for biomedical applications. International Journal of Pharmaceutics 2021, 607, 121020
10. Yunfeng Yan, Li Liu, Hu Xiong, Jason B. Miller, Kejin Zhou, Petra Kos, Kenneth E. Huffman, Sussana Elkassih, John W. Norman, Ryan Carstens, James Kim, John D. Minna, and Daniel J. Siegwart* Functional Polyesters Enable Selective siRNA Delivery to Lung Cancer over Matched Normal Cells. Proceedings of the National Academy of Sciences of the United States of America 2016, 113, E5702-E5710

*以上信息由高级会员个人更新和维护。