周东方

男， 南方医科大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

学习经历
2008.09-2013.06 中国科学院大学，中国科学院长春应用化学研究所、高分子化学与物理专业，博士
2004.09-2008.06 中国地质大学(武汉)，材化学院，材料化学专业，学士
工作经历
2025.05-至今 南方医科大学，第七附属医院，科技副院长
2020.01-至今 南方医科大学，药学院，药剂学，教授
2016.01-2019.12 中国科学院长春应用化学研究所，高分子物理与化学国家重点实验室，副研究员
2013.07-2015.12 中国科学院长春应用化学研究所，高分子物理与化学国家重点实验室，助理研究员

研究领域和兴趣

生物医用高分子、高分子药物递送系统

主要业绩

周东方，南方医科大学第七附属医院科技副院长、药学院教授、珠江医院/广东省人民医院双聘教授，博士生导师，多器官损伤防治全国重点实验室PI，国家“万人计划”青年拔尖人才(2021)。主要从事高分子(金属、蛋白多肽、硼等)药物材料及递送系统用于肿瘤及细菌感染、炎症相关疾病治疗研究。获2020年中/韩国生物材料协会青年科学家奖，入选2020年Journal of Materials Chemistry B新锐科学家。先后主持国家科技重大专项课题（1项）、国自然(3项)、中国科学院-威高研究发展计划、南方医科大学高层次人才引进和杰青培育计划，及骨干参与国家重点研发计划课题(2项)、广东省区域联合基金重点、广州市重点研发计划等项目共10余项。近年来以通讯作者在Advanced Materials、Progress in Polymer Science、Advanced Drug Delivery Reviews、Coordination Chemistry Review、Advanced Science、Nano Letters、ACS Nano、Acta Pharmaceutica Sinica B、Journal of Controlled Release、Bioactive Materials、Biomaterials等期刊发表论文70余篇，其中IF>20的7篇，H指数36，且多篇封面和高倍引。受邀担任Biosafety and Health编委，The Innovation、药学学报(Acta Pharmaceutica Sinica B)、Asian Journal of Pharmaceutical Sciences、Interdisciplinary Medicine、Chinese Chemical Letters、沈阳药科大学学报等青年编委，Bioactive Materials及Pharmaceutics等客座编辑。申请中国发明专利14项，已授权8项。担任中国药理学会抗炎免疫药理专业委员会委员，中国人体健康科技促进会临床检验科学技术转化专业委员会委员，广东省精准医学研究会长青人智库委员会、纳米医学分会、分子影像分会委员等。

代表成果

1. Tao Li, Min Ouyang, Wei Wang, Sijin Chen, Chengxingqiao Wang, Jiahui Lai, Peixian Weng, Zhenhua Li, Yupeng Wang*, Dongfang Zhou*, Engineering Red Blood Cells for Amplified Tumor Dual-Gas Transfusion Therapy. Advanced Materials, 2025, 2503206.
2. Yupeng Wang, Jie Yu, Qiankun Shi, Zhijian Luo, Guanglong Liu, Fan Wu, Zhizhang Wang, Yubin Huang*, Dongfang Zhou*, Engineering endogenous tumor-associated macrophages-targeted biomimetic nano-RBC to reprogram tumor immunosuppressive microenvironment for enhanced chemo-immunotherapy. Advanced Materials, 2021, 33, 2103497.
3. Ting Hou#, Xiaoling Huang#, Jiahui Lai#, Dongfang Zhou*, Intra-tumoral bacteria in breast cancer and intervention strategies. Advanced Drug Delivery Reviews, 2025, 217, 115516.
4. Xiang Li#, Chengxingqiao Wang#, Junhan Liu#, Guifang Deng, Yongqiang Deng, Fang Hu, Yupeng Wang, Dongfang Zhou*, Tailoring tumor cell Golgi Apparatus-targeting self-assembled peptide for effective immunotherapy via reshaping MIF-mediated immunosuppressive network. Advanced Science, 2025, 2415133.
5. Bo Yu#, Wei Sun#, Juntao Lin, Chaoyu Fan, Chengxingqiao Wang, Zhisen Zhang, Yupeng Wang, Yonghua Tang*, Youhui Lin*, Dongfang Zhou*, Using Cu-based metal-organic framework as a comprehensive and powerful anti-oxidant nanozyme for efficient osteoarthritis treatment. Advanced Science, 2024, 2307798.
6. Shaobing Li, Juntao Lin, Chengxinqiao Wang, Yupeng Wang*, Yan Chen*, Dongfang Zhou*, Synergistic metabolic modulation of fibroblast-like synoviocytes with targeted dual prodrug nanoparticles to mitigate rheumatoid arthritis. Acta Pharmaceutica Sinica B, 2025,15,542–556.
7. Yupeng Wang, Lina Wang, Tao Li, Min Ouyang, Hejian Xiong, Dongfang Zhou*, Bimetallic nanoparticles as cascade sensitizing amplifiers for low-dose and robust cancer radio-immunotherapy. Acta Pharmaceutica Sinica B, 2024, 14, 1787–1800.
8. Yupeng Wang#, Yuwei Cong#, Manying Cai, Lina Wang, Dongfang Zhou*, Charge-conversional click polyprodrug nanomedicine for targeted and synergistic cancer therapy. Journal of Controlled Release, 2023, 356, 567–579.
9. Jun-Hui Sun#, Xiaoling Liang#, Manying Cai, Libiao Yan, Zhengju Chen, Lei Guo, Li Jing*, Yupeng Wang* and Dongfang Zhou*, Protein-crowned Micelles for Targeted and Synergistic Tumor-Associated Macrophages Reprogramming to Enhance Cancer Treatment. Nano Letters, 2022, 22, 4410–4420.
10. Yongyan Deng#, Yupeng Wang#, Fan Jia, Weifeng Liu, Dongfang Zhou*, Qiao Jin*, Jian Ji, Tailoring supramolecular prodrug nano-assemblies for reactive nitrogen species-potentiated chemotherapy of liver cancer. ACS Nano, 2021, 15, 8663–8675.

*以上信息由高级会员个人更新和维护。