钱志勇

男， 四川大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

1993-1997年: 四川大学，化学纤维专业，本科学生（工学学士）
1997-2000年: 四川大学，材料学专业，工学硕士，导师：吴大诚教授
2000-2003年: 中科院成都有机化学研究所，高分子化学专业，理学博士，导师：刘孝波教授
2003-2005年: 四川大学，材料学专业，博士后，合作导师：涂铭旌教授，中国工程院院士
2005 - 至今： 四川大学，华西医院生物治疗国家重点实验室，教授
2015 - 至今： 四川大学，二级教授

研究领域和兴趣

高分子材料；生物材料；纳米生物材料；药物递送；组织工程；肿瘤治疗

主要业绩

钱志勇，博士，四川大学二级教授/博导，国家杰出青年基金获得者、国家“万人计划”科技创新领军人才，中国医药生物技术协会纳米生物技术分会主任委员，四川大学华西医院生物治疗国家重点实验室纳米生物医学研究室主任。担任J Biomed Nanotechnol期刊主编，担任Signal Transduction and Targeted Therapy期刊副主编、 Chinese Chemical Letters期刊副主编、J Biological Engineering期刊副主编。主要研究方向是纳米生物材料的构建及其在肿瘤治疗和组织修复中的应用基础研究，以通讯/共同通讯作者身份在Adv Funct Mater, Adv Sci, ACS Nano, Acta Pharm Sinica B, Chin Chem Lett等国内外知名学术期刊发表学术论文100余篇，被他引6000余次。有两组专利技术与企业达成转让协议，其中“注射用多西他赛聚合物胶束”和“注射用紫杉醇聚合物胶束”已经获得2项药物临床试验批件。以第一完成人身份获得2019年度高等学校科学研究优秀成果奖（科学技术）自然科学奖一等奖，以第一完成人身份获得成都市自然科学奖，并获得四川省青年科技奖、获得2019年度“药明康德生命化学研究奖学者奖”，入选中国化学快报主办的第一届CCL优秀青年学者。

代表成果

一，论文:

1. Y. Chen, J. Zhang, X. Liu, S. Wang, J. Tao, Y. Huang, W. Wu, Y. Li, K. Zhou, X. Wei*, S. Chen, X. Li, X. Xu, L. Cardon, Z. Qian*, M. Gou*, Noninvasive in vivo 3D bioprinting. Science Advances. 6 (2020), eaba7406
2. Ying Qu, Bingyang Chu, Xue Wei, Yingying Chen, Yun Yang, Danrong Hu, Jingcao Huang, Fangfang Wang, Mengran Chen, Yuhuan Zheng, Zhiyong Qian*. Cancer-cell-biomimetic nanoparticles for targeted therapy of multiple myeloma based on bone marrow homing. Adv. Mater. 2022, 34 (46): 2107883
3. Chengli Yang, Yang Ming, Kai Zhou, Ying Hao, Danrong Hu, Bingyang Chu, Xinlong He, Yun Yang, Zhiyong Qian*. Macrophage Membrane-Camouflaged shRNA and Doxorubicin: A pH-Dependent Release System for Melanoma Chemo-Immunotherapy. Research. 2022, 2022: 9768687
4. Yun Yang, Qingya Liu, Meng Wang, Lang Li, Yan Yu, Meng Pan, Danrong Hu, Bingyang Chu, Ying Qu, Zhiyong Qian*. Genetically programmable cell membrane-camouflaged nanoparticles for targeted combination therapy of colorectal cancer. Signal Transduction and Targeted Therapy. 2024, 9: 158
5. Yu Chen, Liqun Dai, Kun Shi, Meng Pan, Liping Yuan, and Zhiyong Qian*. Cabazitaxel-loaded Thermosensitive Hydrogel System for Suppressed Orthotopic Colorectal Cancer and Liver Metastasis. Adv Sci. 2024, 11, 2404800
6. Danrong Hu1, Ran Li 1, Yicong Li, Meng Wang, Lu Wang , Shiqi Wang, Hongxin Cheng, Qing Zhang, Chenying Fu, Zhiyong Qian*, Quan Wei*. Inflammation-targeted Nanomedicines Alleviate Oxidative Stress and Reprogram Macrophages Polarization for Myocardial Infarction Treatment. Adv Sci. 2024, 11 (21): 2308910
7. Yang Xu, Zhongwu Bei, Mei Li, Lin Ye, Bingyang Chu, Yu Zhao, Zhiyong Qian*. Biomedical application of materials for external auditory canal: History, challenges, and clinical prospects Bioactive mater.2024, 39: 317-335
8. Qingya Liu, Yun Yang, Meng Pan, Fan Yang, Yan Yu, Zhiyong Qian*. Role of the gut microbiota in tumorigenesis and treatment. Theranostics. 2024; 14(6): 2304-2328
9. Qiang Luo#, Liqun Dai#, Junli Li, Heyanni Chen, Ying Hao, Qing Li, Lili Pan, Chengxiang Song, Zhiyong Qian *, Mao Chen ** Intracellular and extracellular synergistic therapy for restoring macrophage functions via anti-CD47 antibody-conjugated bifunctional nanoparticles in atherosclerosis. Bioactive Materials 34 (2024) 326–337
10. Zhongwu Bei, Linghong Zhang, Jianan Lia, Qi Tong, Kun Shi, Wen Chen, Yan Yu, Ao Sun, Yang Xu, Jie Liu, and Zhiyong Qian,* A smart stimulation-deadhesion and antimicrobial hydrogel for repairing diabetic wounds with methicillin-resistant staphylococcus aureus. Adv Healthcare Mater. 2024, 13, 2303042
11. Fan Yang #, Liqun Dai #, Kun Shi, Qingya Liu, Meng Pan, Dong Mo, Hanzhi Deng, Liping Yuan, Yi Lu, Lili Pan, Tingyu Yang, and Zhiyong Qian*. A facile boronophenylalanine modified polydopamine dual drug-loaded nanoparticles for enhanced anti-tumor immune response in hepatocellular carcinoma comprehensive treatment. Biomaterials. 2024, 305: 122435
12. Meng Wang, DanRong Hu, Yun Yang, Kun Shi, JiaNan Li, QingYa Liu, YiCong Li, Ran Li, Meng Pan, Dong Mo, Wen Chen, XiCheng Li, ZhiYong Qian*. Enhanced Chemo-Immunotherapy Strategy Utilizing Injectable Thermosensitive Hydrogel for the Treatment of Diffuse Peritoneal Metastasis in Advanced Colorectal Cancer. Adv Sci. 2023, 10, (35): 2303819
13. Linghong Zhang, Zhongwu Bei, Tao Li, Zhiyong Qian *. An injectable conductive hydrogel with dual responsive release of rosmarinic acid improves cardiac function and promotes repair after myocardial infarction. Bioactive Materials. 2023, 29: 132-150
14. Kai Zhou, Chengli Yang, Kun Shi, Yue Liu, Danrong Hu, Xinlong He, Yun Yang, Bingyang Chu, Jinrong Peng, Zongke Zhou, Zhiyong Qian*. Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage. Biomaterials. 2023, 295: 122036
15. Liqun Dai, Jie Liu, Xiaosheng Zhao, Yuhao Li, Siming Zhou, Liping Yuan, Diyun Shu, Lili Pan, Yuan-hao Liu, Zhiyong Qian*, BPA-Containing Polydopamine Nanoparticles for Boron Neutron Capture Therapy in a U87 Glioma Orthotopic model. Adv Funct Mater. 2023, 33: 2214145
16. Ruxia Han, Qingya Liu, Yi Lu, Jinrong Peng, Meng Pan, GuiHua Wang, Wen Chen, Yao Xiao, ChengLi Yang, Zhiyong Qian*. Tumor microenvironment-responsive Ag2S-PAsp(DOX)-cRGD nanoparticles-mediated photochemotherapy enhances the immune response for tumor therapy. Biomaterials. 2022, 281: 121328
17. Shijian Feng #, Ying Qu #, Bingyang Chu, Ziyan Yang, Peiwen Li, Peiyu Wang, Qiyu He, Yushi He, Tao Lin, Zhongli Huang*, Zhiyong Qian*. Novel AuPt nanoparticles scavenge reactive oxygen species to attenuate kidney ischemia reperfusion injury. Kidney Int. 2022, 102: 1057-1072
18. Yun Yang, Danrong Hu, Yi Lu, Bingyang Chu, Xinlong He, Yu Chen, Yao Xiao, Chengli Yang, Kai Zhou, Liping Yuan, Zhiyong Qian*. Tumor-Targeted/Reduction-Triggered Composite Multifunctional Nanoparticles for Breast Cancer Chemo-Photothermal Combinational Therapy. Acta Pharm Sinica B. 2022;12(6):2710-2730
19. Xinlong He, Ying Hao, Bingyang Chu, Yun Yang, Ao Sun, Kun Shi, Chengli Yang, Kai Zhou, Ying Qu, He Li, and Zhiyong Qian*. Redox-Activatable Photothermal Therapy and Enzyme-Mediated Tumor Starvation for Synergistic Cancer Therapy. Nano Today. 39 (2021), 101174
20. Qianjun He*, Shengrong Guo, Zhiyong Qian*, Xiaoyuan Chen*. Development of individualized anti-metastasis strategies by engineering nanomedicines. Chem Soc Review. 44 (2015), 6258-6286
21. Jinfeng Liao, Ruxia Han, Yongzhi Wu, Zhiyong Qian*. Review of a new bone tumor therapy strategy based on bifunctional biomaterials. Bone Research. 9 (2021), 18
22. Jinrong Peng, Yao Xiao, Qian Yang, Qingya Liu, Yu Chen, Kun Shi, Ying Hao, Zhiyong Qian*. Intracellular Aggregation of Peptide-Reprogrammed Small Molecule Nanoassemblies Enhances Cancer Chemotherapy and Combinatorial Immunotherapy. Acta Pharm Sinica B. 11 (2021), 1069-1082
23. Yan Yu, Jingrong Peng, Meng Pan, Yang Ming, Yan Li, Liping Yuan, Qingya Liu, Ruxia Han, Ying Hao, Yun Yang, Danrong Hu, He Li, Zhiyong Qian*. A Nonenzymatic Hydrogen Peroxide Electrochemical Sensing and Application in Cancer Diagnosis. Small Methods. 5 (2021), 2001212
24. Xiaohan Zhou, Xinlong He, Kun Shi, Liping Yuan, Yun Yang, Qingya Liu, Yang Ming, Cheng Yi, Zhiyong Qian*. Injectable Thermosensitive Hydrogel containing Erlotinib-loaded Hollow Mesoporous Silica Nanoparticles as Localized Drug Delivery System for NSCLC Therapy. Adv Sci. 7 (2020), 2001442
25. Kun Shi, Bingxin Xue, Yanpeng Jia, Liping Yuan, Ruxia Han, Fan Yang, Jinrong Peng, and Zhiyong Qian*. Sustained co-delivery of gemcitabine and cis-platinum via biodegradable thermo-sensitive hydrogels for synergistic combination therapy of pancreatic cancer. Nano Research. 12 (2019), 1389–1399
26. Jinrong Peng #, Qian Yang #, Yao Xiao, Kun Shi, Qingya Liu, Ying Hao, Fan Yang, Ruxia Han, Zhiyong Qian*. Tumor Microenvironment Responsive Drug-Dye-Peptide Nanoassembly for Enhanced Tumor-Targeting, Penetration, and Photo-Chemo-Immunotherapy. Adv Funct Mater. 29 (2019), 1900004
27. Wei Chen,# Ting Huang,# Kun Shi, Bingyang Chu, Zhiyong Qian*. Chemotaxis-based self-accumulation of surface-engineered mitochondria for cancer therapeutic improvement. Nano Today. 35 (2020), 100966
28. Bingyang Chu, Ying Qu, Xinlong He, Ying Hao, Chengli Yang, Yun Yang, Danrong Hu, Fangfang Wang, Zhiyong Qian*. ROS-responsive camptothecin prodrug nanoparticles for on-demand drug release and combination of chemotherapy and photodynamic therapy. Adv Funct Mater. 30 (2020), 2005918
29. Ying Hao, Yuwen Chen, Xinlong He, Yongyang Yu, Ruxia Han, Yang Li, Chengli Yang, Danrong Hu, ZhiYong Qian*. Polymeric Nanoparticles with ROS-Responsive Prodrug and Platinum Nanozyme for Enhanced Chemophotodynamic Therapy of Colon Cancer. Adv Sci. 7 (2020), 2001853
30. YanPeng Jia, Kun Shi, Fan Yang, JinFeng Liao, RuXia Han, LiPing Yuan, Ying Hao, Meng Pan, Yao Xiao, ZhiYong Qian*, XiaWei Wei*. Multifunctional Nanoparticle Loaded Injectable Thermoresponsive Hydrogel as NIR Controlled Release platform for Local Photothermal Immunotherapy to Prevent Breast Cancer Postoperative Recurrence and Metastases. Adv Fucnt Mater. 30 (2020), 2001059
31. Jinrong Peng, Yao Xiao, Wenting Li, Qian Yang, Liwei Tan, Yanpeng Jia, Ying Qu, Zhiyong Qian*. Photosensitizer micelles together with IDO inhibitor Enhance Cancer Photothermal Therapy and Immunotherapy. Adv Sci. 5 (2018), 1700891
32. Ruxia Han, Yao Xiao, Qian Yang, Meng Pan, Ying Hao, XinLong He, JinRong Peng*, Zhiyong Qian*. Ag2S Nanoparticle-mediated Multiple Ablations Reinvigorates the Immune Response for Enhanced Cancer Photo-immunotherapy. Biomaterials. 264 (2021), 120451
33. Tianlin Zhou, Jinrong Peng, Ying Hao, Kun Shi, Kai Zhou, Yun Yang, Chengli Yang, Xinlong He, Xinmian Chen, and Zhiyong Qian*. The construction of a lymphoma cell-based, DC-targeted vaccine, and its application in lymphoma prevention and cure. Bioactive Materials. 6 (2021), 697-711
34. Fan Yang, Kun Shi, Ying Hao, Yanpeng Jia, Qingya Liu, Yu Chen, Meng Pan, Liping Yuan, Yongyang Yu*, and Zhiyong Qian*. Cyclophosphamide loaded thermo-responsive hydrogel system synergize with a hydrogel cancer vaccine to amplify personalized cancer immunotherapy in a prime-boost manner. Bioactive Materials. 6 (2021), 3036-3048
35. DanRong Hu, Lin Zhong, MengYao Wang, HaoHuan Li, Ying Qu, QingYa Liu, RuXia Han, LiPing Yuan, Kun Shi, JinRong Peng, ZhiYong Qian*. Perfluorocarbon-loaded and redox-activatable photosensitizing agent with oxygen supply for enhancement of fluorescence/photoacoustic imaging guided tumor photodynamic therapy. Adv Funct Mater. 29 (2019), 1806199
36. Qian Yang#, Jinrong Peng#, Kun Shi, Yao Xiao, Qingya Liu, Ruxia Han, Xiawei Wei, Zhiyong Qian*. Rationally designed peptide-conjugated gold/platinum nanosystem with active tumor-targeting for enhancing tumor photothermal-immunotherapy. J Control Rel. 308 (2019), 29–43
37. Ying Qu#, Bingyang Chu#, Minyi Lei, Danrong Hu, Ruoyu Zha, Lin Zhong, Mengyao Wang, Zhiyong Qian*. Redox/pH dual-stimuli responsive camptothecin prodrug nanogels for “on-demand” drug delivery. J Control Rel. 296 (2019), 93-106
38. Chengli Yang, Yuyin Fu, Cheng Huang, Danrong Hu, Kai Zhou, Ying Hao, Bingyang Chu, Xiaohan Zhou, Zhiyong Qian*. Chlorin e6 and CRISPR-Cas9 Dual-Loading System with Deep Penetration for a Synergistic Tumoral Photodynamic-Immunotherapy. Biomaterials. 255 (2020), 120194
39. Xichuan Tang#, Liwei Tan#, Kun Shi, Jinrong Peng, Yao Xiao, Wenting Li, Lijuan Chen, Qian Yang, Zhiyong Qian*. Gold nanorods together with HSP inhibitor-VER-155008 micelles for colon cancer mild-temperature photothermal therapy. Acta Pharmaceut Sinica B. 8 (2018), 587–601
40. MaLing Gou#, Ke Men#,Juan Zhang#, YuHua Li, Jia Song, Shan Luo, HuaShan Shi,YanJun Wen, Gang Guo, MeiJuan Huang, Xia Zhao, ZhiYong Qian*, YuQuanWei. Efficient Inhibition of C-26 Colon Carcinoma by VSVMP Gene Deliveredby Biodegradable Cationic Nanogel Derived from Polyethyleneimine.ACS Nano. 4 (2010), 5573-5584
41. Fang Fang#, ChangYang Gong#, ZhiYong Qian*(通讯作者), XiaoNing Zhang, MaLing Gou, Chao You, LiangXueZhou, JiaGang Liu, Yu Zhang, GangGuo, YingChun Gu, Feng Luo, LiJuan Chen, Xia Zhao, YuQuan Wei. Honokiol Nanoparticles in Thermosensitive Hydrogel: Therapeutic Effects on Malignant Pleural Effusion. ACS Nano. 3 (2009), 4080-4088
42. ShaoZhi Fu, PeiYan Ni, BeiYu Wang, BingYang Chu, JinRong Peng, Lan Zheng, Xia Zhao, Feng Luo, YuQuan Wei, ZhiYong Qian*(通讯作者). In vivo biocompatibility and osteogenesis of electrospun Poly(ε-caprolactone)-Poly(ethylene glycol)-Poly(ε-caprolactone)/nano-hydroxyapatite composite scaffold. Biomaterials. 33 (2012), 8363-8371
43. ShaoZhi Fu, PeiYan Ni, BeiYu Wang, BingYang Chu, Lan Zheng, Feng Luo, JingCong Luo, ZhiYong Qian*(通讯作者). Injectable and thermo-sensitive PEG-PCL-PEG copolymer/Collagen/n-HA hydrogel composite for guided bone regeneration. Biomaterials.33 (2012), 4801-4809
44. ChangYang Gong, Bing Yang, ZhiYong Qian*, Xia Zhao, QinJie Wu, XiaoRong Qi, YuJun Wang, Gang Guo, Bing Kang, Feng Luo, YuQuan Wei. Improving Intraperitoneal Chemotherapeutic Effect and Preventing Postsurgical Adhesions Simultaneously with biodegradable micelles. Nanomedicine-Nanotechnology Biology and Medicine. 8 (2012), 963-973
45. Shuai Shi, Kun Shi, LiWei Tan, Ying Qu, GuoBo Shen, Bingyang Chu, Shuang Zhang, XiaoLan Su, XingYi Li, YuQuan Wei, ZhiYong Qian*. The use of cationic MPEG-PCL-g-PEI micelles for co-delivery of Msurvivin T34A gene and doxorubicin. Biomaterials. 35 (2014), 4536-4547
46. Mei Dai, Xu Xu, Jia Song, ShaoZhi Fu, MaLing Gou, Feng Luo, ZhiYong Qian*(通讯作者). Preparation of camptothecin-loaded PCEC microspheres for the treatment of colorectal peritoneal carcinomatosis and tumor growth in mice. Cancer Letters. 312 (2011), 189-196
47. ChangYang Gong, Shuai Shi, Lan Wu, MaLing Gou, QinQin Yin,QingFa Guo, PengWei Dong, Fan Zhang, FengLuo, Xia Zhao,YuQuan Wei, ZhiYong Qian* (通讯作者). Biodegradable in situ gel-forming controlled drug delivery system based on thermosensitive PCL-PEG-PCL hydrogel. Part 2: Sol-gel-sol transition and drug delivery behavior. Acta Biomater. 5 (2009), 3358-3370
48. YuJun Wang, LiJuan Chen, LiWei Tan, Qian Zhao, BingYang Chu, Feng Luo, ZhiYong Qian*. PEG-PCL based micelle hydrogels as oral docetaxel delivery systems for breast cancer therapy. Biomaterials. 35 (2014), 6972-6985
49. ChangYang Gong, QinJie Wu, YuJun Wang, DouDou Zhang, Feng Luo, Xia Zhao, YuQuan Wei, ZhiYong Qian*. A biodegradable hydrogel system containing curcumin encapsulated in micelles for cutaneous wound healing. Biomaterials. 34 (2013), 6377-6387
50. JinRong Peng, TingTing Qi, JinFeng Liao, BingYang Chu, Qian Yang, WenTing Li, Ying Qu, Feng Luo, ZhiYong Qian*. Controlled Release of Cisplatin from pH-Thermal Dual Responsive Nanogels. Biomaterials. 34 (2013), 8726-8740

二、专利：
1. 钱志勇，魏于全，赵霞。一种温度敏感型三嵌段共聚物及其制备方法和用途。中国发明专利，2008年申请、申请号：200810300751.X；2011年授权、专利号：ZL 200810300751.X
2. 钱志勇，魏于全，赵霞。具溶胶-凝胶转变特性的温敏性三嵌段共聚物及制备方法。中国发明专利，2008年申请、申请号：200810300757.7；2011年授权，专利号：ZL 200810300757.7。
3. 钱志勇，魏于全，赵霞，邓洪新。可降解PCFC-PEI聚合物、制备方法及在药物传递系统中的用途。中国发明专利，2009年申请，申请号：200910308100.X；2011年授权、专利号：ZL200910308100.X。
4. 钱志勇，魏于全，王成，赵霞。负载他克莫司或其药用盐的胶束和冻干制剂、制法及应用。中国发明专利，2011年申请，申请号：201110139610.6；2012年授权、专利号：ZL 201110139610.6。
5. 钱志勇，魏于全，王成，赵霞。二嵌段聚合物负载紫杉烷类药物的胶束和冻干制剂、制法及应用。中国发明专利，2011年申请，申请号：201110139616.3；2012年授权、专利号：ZL 201110139616.3。
6. 钱志勇，魏于全，王成，赵霞。三嵌段聚合物负载紫杉烷类药物的胶束和冻干制剂、制法及应用。中国发明专利，2011年申请，申请号：201110139775.3；2012年授权、专利号：ZL 201110139775.3。
7. 魏于全，钱志勇，杨莉，赵霞。PEG-PCL-PEG的新用途及装载抗原的混合物。中国发明专利，2010年申请，申请号：201010241625.9；2012年授权、专利号：ZL201010241625.9。
8. 钱志勇，魏于全，赵霞。MPEG-PLA两嵌段共聚物在制备医用防粘连材料中的用途。中国发明专利，2010年申请，申请号：201010133541.3；2012年授权、专利号：ZL 201010133541.3。
9. 钱志勇，魏于全，赵霞，巩长旸。PCL-PEG-PCL三嵌段共聚物在制备医用防粘连材料中的用途。中国发明专利，2010年申请，申请号：201010138739.0；2013年授权、专利号：ZL 201010138739.0。
10. 钱志勇，魏于全，苟马玲，赵霞。一种时间-温度变色指示器及其应用和使用方法。中国发明专利，2011年申请，申请号：201110167000.7；2013年授权、专利号：ZL 201110167000.7。
11. 钱志勇，魏于全。PDLLA-PEG-PDLLA三嵌段共聚物在制备医用防粘连材料中的用途。中国发明专利，2013年申请，专利号：ZL 201310185030.X。2015年3月4日授权；
12. 钱志勇，罗静聪，杨志明，赵霞，魏于全。一种复合材料及其制备方法和用途。中国发明专利，2012年申请，申请号：201210253461.0；2015年授权、专利号：ZL201210253461.0。
13. 赵杭，钱志勇，魏霞蔚。MPEG-PTMC两嵌段共聚物载药胶束及其制备方法和应用。中国发明专利，2016年申请，申请号：201610006593.1；2019年授权、专利号：ZL 201610006593.1。
14. 钱志勇，何鑫业，魏霞蔚。改性γ-聚谷氨酸凝胶止血材料及其制备方法和应用。中国发明专利，2020年申请，申请号：202010540115.5；2022年授权，专利号：ZL202010540115.5。
15. 钱志勇，于艳。掺杂N且负载PtNi双金属的石墨烯复合材料及其制备方法和用途。中国发明专利，2020年申请，申请号：202010858631.2；2021年授权，专利号：ZL 202010858631.2。
16. 钱志勇,楚冰洋,魏霞蔚. 喜树碱前药凝胶及其制备方法和用途。中国发明专利，2019年申请，申请号：201910062943.X；2022年授权，专利号：ZL 201910062943.X。
17. 钱志勇，郝颖。微针释药装置及制造方法、皮肤疾病治疗装置。中国发明专利，2020年申请，申请号：202010272216.9；2022年授权，专利号：ZL 202010272216.9。
18. 钱志勇，楚冰洋。一种喜树碱-光敏剂前药及其制备方法和应用。中国发明专利，2020年申请，申请号：202010885949.X；2022年授权，专利号：ZL 202010885949.X。
19. 钱志勇，杨成莉，周凯，胡丹蓉。一种软骨修复纳米凝胶复合体系的制备方法及应用。中国发明专利，2021年申请，申请号：202111198215.5；2022年授权，专利号：ZL202111198215.5。
20. 罗静聪，李加乐，钱志勇。一种聚合物微球/小肠粘膜下层复合材料、其制备方法及其用途。中国发明专利，2021年申请，申请号：202111194089.6；2022年授权，专利号：ZL202111194089.6。
21. 钱志勇，孙鳌，魏霞蔚。一种水凝胶及其制备方法和应用。中国发明专利，2022年申请，申请号：202211178884.0；2023年授权，专利号：ZL202211178884.0。
22. 杨成莉; 周凯; 胡丹蓉; 钱志勇。具有滑膜炎症抑制功能的纳米材料的制备方法及应用。中国发明专利，2021年申请，申请号：202111197427.1；2023年授权，专利号：ZL202111197427.1。

三、著作
1. Ying Qu, XiaWei Wei, Zhiyong Qian*. “Thermosensitive Biomaterials in Tissue Engineering”. Chapter 15 in RSC Smart Materials No. 24. Smart Materials for Tissue Engineering: Fundamental Principles. Edited by Qun Wang. © The Royal Society of Chemistry 2017. Published by the Royal Society of Chemistry
2. XiaWei Wei, Gang Guo, ChangYang Gong, MaLing Gou, and Zhiyong Qian (通讯作者)*. “Biodegradable polymers: Research and Applications”. Chapter 12 in the book of “A Handbook of Applied Biopolymer Technology: Synthesis, Degradation and Applications” (RSC Green Chemistry Series). 2011, ISBN: 978-1-84973-151-5. Editors: SK Sharma and Ackmez Mudhoo. RSC Publisher, United Kingdom.
3. ChangYang Gong, Shuai Shi, PengWei Dong, MaLing Gou, XingYi Li, YuQuan Wei and ZhiYong Qian (通讯作者)*, A Novel Thermosensitive Composite Hydrogel Based on Poly(ethylene glycol)-poly(ε-caprolactone)-poly(ethylene glycol) (PECE) Copolymer and Pluronic F127. Chapter 2 in the book of “Polymer Aging, Stabilizers and Amphiphilic Block Copolymers” (“Polymer Science and Technology Series”). Editors: Liudvikas Segewicz and Marijus Petrowsky. Nova Publishers.页: 29-43，出版年: 2010 （ISBN: 978-1-60692-928-5）

*以上信息由高级会员个人更新和维护。