谷慧

女， 湖南科技大学化学化工学院， 教授/研究员/教授级高工或同等级别

学习/工作经历

匹兹堡大学（University of Pittsburgh, PITT），美国宾夕法尼亚州匹兹堡
联合培养博士，分析化学（UPLC–电化学检测与微透析联用体内分析），2013 年09 月–
2014 年09 月
导师：Prof. Stephen G. Weber
• 华东师范大学（ECNU），中国上海
博士，分析化学（基于纳米材料的电化学传感器；在线微透析–电化学系统用于神经化学
湖南科技大学，中国长沙
教授，2025 年09 月– 至今
• 哥德堡大学，瑞典哥德堡
Marie Curie 博士后，2022 年09 月– 2025 年08 月
• 湖南科技大学，中国长沙
副教授，2019 年12 月– 2024 年12 月
• 湖南师范大学，中国长沙
客座研究员，2018 年07 月– 2022 年08 月
• 湖南科技大学，中国长沙
讲师，2015 年10 月– 2019 年12 月
物质体内分析），2010 年09 月– 2015 年05 月
导师：施国跃教授
• 湖南师范大学，中国长沙
工学学士，制药工程，2006 年09 月– 2010 年06 月

研究领域和兴趣

生物电分析化学

主要业绩

谷慧，女，欧盟玛丽·居里学者，湖南科技大学化学化工学院教授，湖南科技大学化学化工学院副院长，湖南省神经修复重点实验室客座研究员。2010–2015 年于华东师范大学获得分析化学博士学位，期间于 2013–2014 年赴美国匹兹堡大学开展联合培养研究。主要从事电化学微/纳米传感与在体生物分析方法学研究，研究方向包括活体脑内神经递质及活性分子的高时空分辨检测、应激颗粒（Stress Granules）与神经囊泡相互作用的电化学机制、神经系统疾病相关的生化分析策略，以及环境水体污染物的便携式电化学检测。主持欧盟地平线项目、国家自然科学基金面上项目和青年项目，以及湖南省优秀青年项目等多项省部级科研项目。以（共同）通讯作者在 Journal of the American Chemical Society、Angewandte Chemie International Edition 等国际权威期刊发表学术论文 40 篇，相关研究成果在电化学生物传感、神经化学分析及单实体电化学测量领域产生了重要学术影响。已获授权国家发明专利 2 项，多次受邀在国内外重要学术会议作口头报告。现为中国化学会资深会员、“玛丽·居里学者华人学会”秘书处主任。

代表成果

Hui Gu*, Chaoyi Gu, Andre Du Toit, Andrew G. Ewing*, Two-nanosensor electrochemical
profiling of catecholamine vesicle interactions with acute and chronic stress granules in living
cells, Angew. Chem. Int. Ed. 2026, e25900.
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• Xingchen Tan#, Wenhui Wang#, Cong Luo, Qian Wang, Huihui Wang, Hui Pan, Haoyue
Xiang, Hui Gu*, In vivo ratiometric electrochemical detection of hypochlorous acid in living
brains using a methylene blue-benzoyl-based microsensor, Anal. Chem. 2026, 98, 1710-1717.
• Hui Gu, Chaoyi Gu, Nicolas Locker, Andrew G. Ewing; Amperometry and Electron Microscopy
show Stress Granules Induce Homotypic Fusion of Catecholamine Vesicles, Angew.
Chem. Int. Ed. 2024, 3, e202400422.
• Qiuyue Chen#, Ruizhi Lin#, Wenhui Wang, Yimei Zuo, Yi Zhuo, Yanyan Yu, Shu Chen, Shu
Chen, Hui Gu*; Efficient Electrochemical Microsensor for the Simultaneous Measurement of
Hydrogen Peroxide and Ascorbic Acid in Living Brains, Analytical Chemistry 2024, 96(17):
6683–6691.
• Yimei Zuo#, Sisi Wang#, Ruizhi Lin, Gelei Xiao, Shu Chen, Rongjin Zeng, Hui Gu*;
A portable electrochemical microsensor for in-site measurement of dissolved oxygen and
hydrogen sulfide in natural water, Talanta 2023, 256, 124269.
• Yu Luo; Ruizhi Lin; Yimei Zuo; Ziyi Zhang; Yi Zhuo; Ming Lu; Shu Chen; Hui Gu*;
Efficient Electrochemical Microsensor for In Vivo Monitoring of H2O2 in PD Mouse Brain:
Rational Design and Synthesis of Recognition Molecules, Analytical Chemistry 2022, 94(25):
9130–9139.
• Ziyi Zhang, Mengyin Li, Yimei Zuo, Shu Chen*, Yi Zhuo, Ming Lu, Guoyue Shi, Hui Gu*.
In Vivo Monitoring of pH in Subacute PD Mouse Brains with a Ratiometric Electrochemical
Microsensor Based on Poly(melamine) Films, ACS Sensors 2022, 7(1): 235–244.
• Chenchen Li#, Yi Zhuo#, Xia Xiao, Shuangfu Li, Kai Han*, Ming Lu, Jiaxin Zhang, Shu
Chen, Hui Gu*, Facile electrochemical microbiosensor based on in situ self-assembly of Ag
nanoparticles coated on Ti3C2Tx for in vivo measurements of chloride ions in the PD mouse
brain, Analytical Chemistry 2021, 93, 21, 7647–7656.
• Xia Xiao, Chenchen Li, Yuzhi Liu, Yaqian Feng, Kai Han, Haoyue Xiang*, Guoyue Shi,
Hui Gu*, A ratiometric electrochemical microsensor for monitoring of chloride ion in vivo,
Analyst 2021, 146, 6202–6210.
• Yimin Jiang#, Xia Xiao#, Chenchen Li, Yu Luo, Shu Chen, Guoyue Shi, Kai Han, Hui
Gu*, Facile ratiometric electrochemical sensor for in vivo/online repetitive measurements of
cerebral ascorbic acid in brain microdiaysate, Analytical Chemistry 2020, 92, 5: 3981–3989.
• Hui Gu*, Yanqiu Guo, Xia Xiao, Chenchen Li, Guoyue Shi, Jian He*, Double molecular
recognition strategy based on boronic acid–diol and NHS ester–amine for selective electrochemical
detection of cerebral dopamine, Analytical and Bioanalytical Chemistry 2020, 412,
3727–3736.
• Hui Gu*, Qi Hou, Yu Liu, Yujie Cai, Yanqiu Guo, Haoyue Xiang, Shu Chen*, On-line
regeneration of electrochemical biosensor for in vivo repetitive measurements of striatum
Cu2+ under global cerebral ischemia/reperfusion events, Biosensensors Bioelectronics 2019,
135: 111–119.
• Hui Gu*, Yu Liu, Tianyao Ren, Wenbiao Xia, Yanqiu Guo, Guoyue Shi, An electrochemical
biosensor based on double molecular recognition for selective monitoring of cerebral
dopamine dynamics at 4 min interval, Sensors Actuators B: Chemical 2019, 287: 356–363.
2
• Hui Gu*, Yidan Xing, Ping Xiong, Huiling Tang, Chenchen Li, Shu Chen, Rongjin Zeng,
Kai Han*, Guoyue Shi, Three-dimensional porous Ti3C2Tx MXene–graphene hybrid films
for glucose biosensing, ACS Applied Nano Materials 2019, 2: 6537–6545.
• Hui Gu*, Ping Xiong, Huiling Tang, Shu Chen, Yunfei Long, Guoyue Shi, In vivo monitoring
of cerebral glucose with an updated on-line electroanalytical system, Analytical and
Bioanalytical Chemistry 2019, 411, 5929–5935.
• Huiling Tang, Dehao Cai, Tianyao Ren, Ping Xiong, Yu Liu, Hui Gu*, Guoyue Shi, Fabrication
of a low background signal glucose biosensor with 3D network materials as the
electrocatalyst, Analytical Biochemistry 2019, 567, 63–71.
• Hui Gu*, Huiling Tang, Ping Xiong, Zhihua Zhou*, Biomarkers-based Biosensing and Bioimaging
with Graphene for Cancer Diagnosis, Nanomaterials 2019, 9, 130.
• Hui Gu, Varner Erika L., Groskreutz Stephen R., Michael Adrian C., Weber Stephen G.*, In
vivo monitoring of dopamine by microdialysis with 1 min temporal resolution using online
capillary liquid chromatography with electrochemical detection, Analytical Chemistry 2015,
87(12): 6088–6094.

*以上信息由高级会员个人更新和维护。