赵新锋

男， 西北大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

1997.09-2001.07 西北大学 化学 理学学士
2003.09-2005.07 西安交通大学 应用化学 工学硕士
2006.03-2009.06 西安交通大学 药理学 医学博士
2009.07-2013.05 西北大学 讲师
2010.09-2011.10 剑桥大学 博士后
2013.06-2015.12 西北大学 副教授
2016.01-至今 西北大学 教授
2017.03-2018.03 普渡大学 高级访问学者

研究领域和兴趣

亲和分析技术及应用

主要业绩

赵新锋，二级教授，博士生导师，西北大学中药学/药学学科负责人，西部资源生物与现代生物技术教育部重点实验室副主任。中国中医药信息学会科技创新与成果转化分会常务理事，中国药学会药物分析专业委员会委员，《Chinese Medicine》、《药物分析》和《世界科学技术-中医药现代化》等杂志编委。2010年在英国剑桥大学药理学系进行博士后研究，2017年在美国普渡大学访学。主要研究方向为药物亲和分析新方法的创建及其应用研究。主持国家自然科学基金项目5 项，国家“重大新药创制”重大专项项目2项，陕西省重点研发计划重点产业创新链项目1项，企业委托课题5项；在Science, Journal of the American Chemical Society, Chemical Science, Analytical Chemistry和Journal of Medicinal Chemistry等杂志发表学术论文100余篇；获中国发明专利授权6项，出版专著1部，获软件著作权1项；获陕西省科学技术一等奖2项、陕西高等学校科学技术一等奖4项；获三秦英才特殊支持计划科技创新领军人才、陕西省中青年科技创新领军人才和西安青年科技人才等荣誉称号。

代表成果

1. Qian Li, Longfei Liu, Dake Mao, Yuyan Yu, Weili Li, Xinfeng Zhao*, Chengde Mao*, ATP-triggered, allosteric self-assembly of DNA nanostructures, ournal of the American Chemical Society, 2020, 142, 665-668
2. Qi Liang, Jianyu He, Xue Zhao, Yan Xue, Haiyue Zuo, Ru Xu, Yan Jin, Jing Wang, Qian Li, Xinfeng Zhao*, Selective Discovery of GPCR Ligands within DNA-Encoded Chemical Libraries Derived from Natural products: A Case Study on Antagonists of Angiotensin II Type I Receptor, Journal of Medicinal Chemistry, 2021, 64, 4196-4205
3. Rui Tian, Jiatai Yin, Qingqing Yao, Taotao Wang, Jiahuan Chen, Qi Liang, Qian Li*, Xinfeng Zhao*, llostery Responsive Chromatographic Method for Screening Potential Allosteric Modulator of Beta2-adrenoceptor from a Natural Product-Derived DNA-Encoded Chemical Library, Analytical Chemistry, 2022, 94, 9048−9057
4. Qian Li, Guowei Yin, Jing Wang, Linkang Li, Qi Liang, Xue Zhao, Yuanyuan Chen, Xiaohui Zheng, Xinfeng Zhao*, An emerging paradigm to develop analytical methods based on immobilized transmembrane proteins and its applications in drug discovery, Trends in Analytical Chemistry, 2022, 157, 116728
5. Haiyue Zuo, Ting Li, Dandan Zhang, Jing Ma, Zilong Zhang, Yuanyuan Ou, Xiaojuan Lian, Jiatai Yin, Qian Li, Xinfeng Zhao*, Enhancing Chromatographic Performance of Immobilized Angiotensin II Type 1 Receptor by Strain-Promoted Alkyne Azide Cycloaddition through Genetically Encoded Unnatural Amino Acid, Analytical Chemistry, 2022, 94, 15711-15719
6. Dandan Zhang, Jing Ma, Xinxin Zheng, Zilong Zhang, Xiaojuan Lian, Xue Zhao, Xinfeng Zhao*, Fabrication of a bioconjugated dual-functional SERS probe for facile compound screening and detection, Biosensors and Bioelectronics 2023, 234, 115369
7. Sidi Cun, Zilong Zhang, Yunshan Wang, Ruoxue Bai, Meizhi Jiao, Qian Li, Xinfeng Zhao*, Target-binding compound screening and detecting approach for DNA-encoded library utilizing affinity magnetic levitation, Chemical Engineering Journal, 2025, 517,164318
8. Xinxin Zheng, Sidi Cun, Jiatai Yin, Xue Zhao, Yunshan Wang, Jing Wang, Qian Li, Xinfeng Zhao*, Immobilizing the Endogenous 5-Hydroxytryptamine Transporter by Ligand-Directed and Proximity-Catalyzed Acyl Imidazole Chemistry for Affinity Chromatographic Analysis, Analytical Chemistry, 2025, 97(18), 10046-10055
9. Xue Zhao, Mingxuan Kang, Sidi Cun, Ruoxue Bai, Mei Lv, Tongtong Li, Yajun Zhang, Xinfeng Zhao*, Affinity-Driven Two-Step Immobilization of Endogenous Natural GABAA Receptor to Quantify Drug–Protein Analysis with Enhanced Sensitivity and Accuracy, Analytical Chemistry, 2025, 97(48), 26918-26928
10. Yunshan Wang, Nan Lu, Peiyao Wu, Yue Chu, Yonghao Xing, Jing Wang, Xinfeng Zhao*, An Allosteric Assay for Identifying Ligands Binding to β2 Adrenergic Receptor by Surface-Enhanced Raman Scattering (SERS)-Active Nanoparticles, Analytical Chemistry, 2026, 98(6), 4895–4904

*以上信息由高级会员个人更新和维护。