张亮亮

男， 广西师范大学， 教授/研究员/教授级高工或同等级别

学习/工作经历

2003.09至2007.06 湖南大学化学化工学院 本科生
2007.09至2009.12 湖南大学化学化工学院 硕士研究生
2009.12至2013.06 湖南大学化学化工学院 博士研究生
2013.07至2015.12 广西师范大学化学与药学学院 专任教师/讲师
2016.01至2019.05 广西师范大学化学与药学学院 专任教师/副教授
2019.06至2020.12 广西师范大学化学与药学学院 副院长/教授
2020.12至2021.07 广西师范大学团委 副书记（主持工作）/教授
2021.07至2023.12 广西师范大学团委 书记/教授
2021.07至今 广西师范大学省部共建要用资源化学与药物分子工程国家重点实验室 常务副主任/教授

研究领域和兴趣

生命分析化学；近红外光调控的分子感知与活体诊疗探针

主要业绩

张亮亮，广西师范大学教授，博士生导师，广西化学化工学会常务理事、分析测试专业委员会主任，中国分析测试协会生物传感专业委员会委员、青年学术委员委员。入选广西首批八桂青年拔尖人才，是广西青年五四奖章、广西青年科技奖以及广西杰出青年科学基金获得者。主要从事光响应智能探针设计构建、活体成像与诊疗等方向的研究，在Science Advances，Chemical Science，Analytical Chemistry等期刊发表SCI论文60余篇。以第一完成人获得广西自然科学二等奖1项，作为主要完成人获得广西自然科学一等奖2项（分别排名第二、第五）。

代表成果

1. Lixian Huang, Fei Lv, Yidong Bin, Jingjin Zhao, Caiying Li, Shulin Zhao*, Shengqiang Hu, Liangliang Zhang*, A hydrogen sulfide-activated NIR-II fluorescence/NIR-I photoacoustic dual-ratiometric nanoprobe with unique recognition reaction for precise visual diagnosis of hepatitis disease, Small, 2025, 21(23), 2501269.
2. Xiaofeng Bi#, Jinyue Feng#, Xiyuan Feng, Dianpeng Li, Yumin Wang*, Shulin Zhao, Liangliang Zhang*, APE1-activated and NIR-II photothermal-enhanced chemodynamic therapy guided by amplified fluorescence imaging, Analytical Chemistry, 2025, 97, 1748-1757.
3. Xiyuan Feng#, Xiaofeng Bi, Jinyue Feng, Shengqiang Hu, Yumin Wang*, Shulin Zhao, Liangliang Zhang*, Proximity-induced bipedal DNA walker for accurately visualizing microRNA in living cancer cell, Analytical Chemistry, 2024, 96, 10669-10676.
4. Liuyan Zhou#, Xiaokun Li#, Luyin Wang, Zhihong Zhou, Shengqiang Hu*, Shulin Zhao, Liangliang Zhang*, Fluid multivalent recognition accelerating and boosting upconversion luminescence-activated DNA nanomachines for rapid and sensitive in vivo imaging, Analytical Chemistry, 2023, 95, 18497-18503.
5. Lifang Pang#, Xiaolan Tang#, Lijiao Yao, Liuyan Zhou, Shenqiang Hu*, Shulin Zhao, Liangliang Zhang*, Smart down/upconversion nanomachines integrated with “AND” logic computation and enzyme-free amplification for NIR-II fluorescence-assisted precise and enhanced photodynamic therapy, Chemical Science, 2023, 14, 3070-3075.
6. Shengqiang Hu#, Lixian Huang#, Liuyan Zhou, Tingchan Wu, Shulin Zhao, Liangliang Zhang*, Single-excitation triple-emission down-/up-conversion nanoassemblies for tumor microenvironment-enhanced ratiometric NIR-II fluorescence imaging and chemo-/photodynamic combination therapy, Analytical Chemistry, 2023, 95, 3830-3839
7. Shulong Wang, Yanli Luo, Changchun Wen, Shulin Zhao*, Liangliang Zhang*, An autocatalytically-activatable hydrogen peroxide photoacoustic sensor for in situ visualization precise diagnosis and drug intervention tracing in diabetes syndrome, Biosensors and Bioelectronics, 2023, 222, 114964.
8. Shulong Wang, Liangliang Zhang*, Yanni Luo, Yulong Bai, Yong Huang, Shulin Zhao*, A circular dichroism and photoacoustic dual-mode probe for detection in vitro and imaging in vivo of hydroxyl radicals, Analytical Chemistry, 2022, 94(5), 2453-2464.
9. Shulong Wang, Liangliang Zhang*, Jingjin Zhao, Min He, Yong Huang, Shulin Zhao*, A tumor microenvironment–induced absorption red-shifted polymer nanoparticle for simultaneously activated photoacoustic imaging and photothermal therapy, Science Advances, 2021, 7, eabe3588.
10. Chaobang Zhang, Zhidong Qiu, Liangliang Zhang*, Qiufang Pang, Zhengmin Yang, Jiang-Ke Qin, Hong Liang, Shulin Zhao*, Design and synthesis of a ratiometric photoacoustic imaging probe activated by selenol for visual monitoring of pathological progression of autoimmune hepatitis, Chemical Science, 2021, 12(13), 4883-4888.

*以上信息由高级会员个人更新和维护。